The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries

Kidney transplantation (KT) is a preferred treatment for end-stage renal disease (ESRD) because it offers better long-term survival and cost-effectiveness compared to dialysis. Significant global disparities persist in access to KT, particularly in low- and middle-income countries (LMICs). This stud...

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Main Authors: Nguyen Xuong Duong, Minh Sam Thai, Ngoc Sinh Tran, Khac Chuan Hoang, Quy Thuan Chau, Xuan Thai Ngo, Trung Toan Duong, Tan Ho Trong Truong, Hanh Thi Tuyet Ngo, Dat Tien Nguyen, Khoa Quy, Tien Dat Hoang, David-Dan Nguyen, Narmina Khanmammadova Onder, Dinno Francis Mendiola, Anh Tuan Mai, Muhammed A. Moukhtar Hammad, Huy Gia Vuong, Ho Yee Tiong, Se Young Choi, Tuan Thanh Nguyen
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Société Internationale d’Urologie Journal
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Online Access:https://www.mdpi.com/2563-6499/5/5/54
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author Nguyen Xuong Duong
Minh Sam Thai
Ngoc Sinh Tran
Khac Chuan Hoang
Quy Thuan Chau
Xuan Thai Ngo
Trung Toan Duong
Tan Ho Trong Truong
Hanh Thi Tuyet Ngo
Dat Tien Nguyen
Khoa Quy
Tien Dat Hoang
David-Dan Nguyen
Narmina Khanmammadova Onder
Dinno Francis Mendiola
Anh Tuan Mai
Muhammed A. Moukhtar Hammad
Huy Gia Vuong
Ho Yee Tiong
Se Young Choi
Tuan Thanh Nguyen
author_facet Nguyen Xuong Duong
Minh Sam Thai
Ngoc Sinh Tran
Khac Chuan Hoang
Quy Thuan Chau
Xuan Thai Ngo
Trung Toan Duong
Tan Ho Trong Truong
Hanh Thi Tuyet Ngo
Dat Tien Nguyen
Khoa Quy
Tien Dat Hoang
David-Dan Nguyen
Narmina Khanmammadova Onder
Dinno Francis Mendiola
Anh Tuan Mai
Muhammed A. Moukhtar Hammad
Huy Gia Vuong
Ho Yee Tiong
Se Young Choi
Tuan Thanh Nguyen
author_sort Nguyen Xuong Duong
collection DOAJ
description Kidney transplantation (KT) is a preferred treatment for end-stage renal disease (ESRD) because it offers better long-term survival and cost-effectiveness compared to dialysis. Significant global disparities persist in access to KT, particularly in low- and middle-income countries (LMICs). This study aims to assess the epidemiology and outcomes of KT in LMICs while examining the relationship between a country’s income level and its KT prevalence. A systematic review of the literature was conducted, with searches of PubMed, Scopus, and Web of Science from inception to 31 May 2024. Relevant articles reporting on the epidemiology and outcomes of KT or ESRD patients undergoing kidney replacement therapy (KRT) in LMICs were included. A total of 8054 articles were identified, with 972 articles selected for full-text screening after initial title and abstract review. Following full-text screening, 35 articles met the inclusion criteria. The data showed significant variation in KRT and KT prevalence across different geographical locations. Higher-income countries within LMICs tended to have higher KT prevalence rates. Barriers such as inadequate healthcare infrastructure, limited financial resources, and insufficient organ donation frameworks were identified as contributing factors to the low KT rates in these regions. The study highlights the disparities in KT access and prevalence in LMICs, underscoring the need for targeted interventions and international collaboration to address these gaps. Efforts to increase both living and deceased donor transplants, expand health system capacity, and incorporate KT in healthcare planning are needed to close this gap. Global partnerships spearheaded by organizations such as The Transplantation Society (TTS) and the International Society of Nephrology (ISN) are crucial for improving KT rates and outcomes in LMICs.
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spelling doaj-art-0046c32cd4e344e9aa948b701066fb862025-08-20T03:55:23ZengMDPI AGSociété Internationale d’Urologie Journal2563-64992024-10-015534936010.3390/siuj5050054The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income CountriesNguyen Xuong Duong0Minh Sam Thai1Ngoc Sinh Tran2Khac Chuan Hoang3Quy Thuan Chau4Xuan Thai Ngo5Trung Toan Duong6Tan Ho Trong Truong7Hanh Thi Tuyet Ngo8Dat Tien Nguyen9Khoa Quy10Tien Dat Hoang11David-Dan Nguyen12Narmina Khanmammadova Onder13Dinno Francis Mendiola14Anh Tuan Mai15Muhammed A. Moukhtar Hammad16Huy Gia Vuong17Ho Yee Tiong18Se Young Choi19Tuan Thanh Nguyen20Department of Urology, Graduate School of Medical Sciences, University of Yamanashi, Chuo-City 409-3898, JapanDepartment of Urology, Cho Ray Hospital, Ho Chi Minh City 700000, VietnamDepartment of Urology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, VietnamDepartment of Urology, Cho Ray Hospital, Ho Chi Minh City 700000, VietnamDepartment of Urology, Cho Ray Hospital, Ho Chi Minh City 700000, VietnamDepartment of Urology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, VietnamDepartment of Hemodialysis, Cho Ray Hospital, Ho Chi Minh City 700000, VietnamDepartment of Urology, Cho Ray Hospital, Ho Chi Minh City 700000, VietnamDepartment of Pathology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, VietnamDepartment of Urology, Binh Dan Hospital, Ho Chi Minh City 700000, VietnamDepartment of Medicine, Vin University, Hanoi 10000, VietnamDepartment of Urology, Cho Ray Hospital, Ho Chi Minh City 700000, VietnamDivision of Urology, University of Toronto, Toronto, ON M5S 1A1, CanadaDepartment of Urology, University of California, Irvine, CA 92697, USADepartment of Urology, University of Miami, Coral Gables, FL 33146, USADepartment of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 70000, VietnamDepartment of Urology, University of California, Irvine, CA 92697, USADepartment of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USADepartment of Urology, National University Hospital, Singapore 119228, SingaporeDepartment of Urology, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul 06973, Republic of KoreaDepartment of Urology, Cho Ray Hospital, Ho Chi Minh City 700000, VietnamKidney transplantation (KT) is a preferred treatment for end-stage renal disease (ESRD) because it offers better long-term survival and cost-effectiveness compared to dialysis. Significant global disparities persist in access to KT, particularly in low- and middle-income countries (LMICs). This study aims to assess the epidemiology and outcomes of KT in LMICs while examining the relationship between a country’s income level and its KT prevalence. A systematic review of the literature was conducted, with searches of PubMed, Scopus, and Web of Science from inception to 31 May 2024. Relevant articles reporting on the epidemiology and outcomes of KT or ESRD patients undergoing kidney replacement therapy (KRT) in LMICs were included. A total of 8054 articles were identified, with 972 articles selected for full-text screening after initial title and abstract review. Following full-text screening, 35 articles met the inclusion criteria. The data showed significant variation in KRT and KT prevalence across different geographical locations. Higher-income countries within LMICs tended to have higher KT prevalence rates. Barriers such as inadequate healthcare infrastructure, limited financial resources, and insufficient organ donation frameworks were identified as contributing factors to the low KT rates in these regions. The study highlights the disparities in KT access and prevalence in LMICs, underscoring the need for targeted interventions and international collaboration to address these gaps. Efforts to increase both living and deceased donor transplants, expand health system capacity, and incorporate KT in healthcare planning are needed to close this gap. Global partnerships spearheaded by organizations such as The Transplantation Society (TTS) and the International Society of Nephrology (ISN) are crucial for improving KT rates and outcomes in LMICs.https://www.mdpi.com/2563-6499/5/5/54kidney transplantationlow- and middle-income countriessocioeconomic factors
spellingShingle Nguyen Xuong Duong
Minh Sam Thai
Ngoc Sinh Tran
Khac Chuan Hoang
Quy Thuan Chau
Xuan Thai Ngo
Trung Toan Duong
Tan Ho Trong Truong
Hanh Thi Tuyet Ngo
Dat Tien Nguyen
Khoa Quy
Tien Dat Hoang
David-Dan Nguyen
Narmina Khanmammadova Onder
Dinno Francis Mendiola
Anh Tuan Mai
Muhammed A. Moukhtar Hammad
Huy Gia Vuong
Ho Yee Tiong
Se Young Choi
Tuan Thanh Nguyen
The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries
Société Internationale d’Urologie Journal
kidney transplantation
low- and middle-income countries
socioeconomic factors
title The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries
title_full The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries
title_fullStr The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries
title_full_unstemmed The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries
title_short The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries
title_sort impact of socioeconomic factors on kidney transplantation a systematic review of low and middle income countries
topic kidney transplantation
low- and middle-income countries
socioeconomic factors
url https://www.mdpi.com/2563-6499/5/5/54
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