Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis
Introduction: Surgical site infection (SSI) constitutes a substantial complication after knee arthroplasty, contributing to notable morbidity. This study aimed to review the existing literature on the incidence and risk factors of SSI following knee arthroplasty. Methods: A systematic search was...
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| Format: | Article |
| Language: | English |
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Shahid Beheshti University of Medical Sciences
2025-01-01
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| Series: | Archives of Academic Emergency Medicine |
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| Online Access: | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2543 |
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| author | Ayub Bagheri Alireza Sharifi Niknafs Bahar Farhadi Seyed Amirhossein Mazhari Parnia Karimian Nafiseh Hekmati Pour Hamid Hojjati Iman Nosratabadi Azadeh Emami Reza Salehi |
| author_facet | Ayub Bagheri Alireza Sharifi Niknafs Bahar Farhadi Seyed Amirhossein Mazhari Parnia Karimian Nafiseh Hekmati Pour Hamid Hojjati Iman Nosratabadi Azadeh Emami Reza Salehi |
| author_sort | Ayub Bagheri |
| collection | DOAJ |
| description |
Introduction: Surgical site infection (SSI) constitutes a substantial complication after knee arthroplasty, contributing to notable morbidity. This study aimed to review the existing literature on the incidence and risk factors of SSI following knee arthroplasty.
Methods: A systematic search was undertaken across various international electronic databases, including Scopus, PubMed, Web of Science, and Persian electronic databases such as Iranmedex and the Scientific Information Database. The search strategy involved the use of keywords derived from Medical Subject Headings, such as “incidence”, “Surgical wound infection”, “Surgical site infection”, and “Arthroplasty”, covering records from the earliest available up to March 17, 2024.
Results: The study incorporated a collective participant group of 1,366,494 knee arthroplasty procedures from twenty-three chosen studies. The pooled incidence rate of SSI after knee arthroplasty was 1.7% (95% confidence interval (CI): 1.1% to 2.6%; I²=99.687%; P<0.001). The Odds Ratio (OR) for the incidence of SSI in males was observed to be significantly higher than that in females (OR: 1.617; 95% CI: 1.380 to 1.894; Z=5.951; P<0.001). The pooled incidence of SSI among diabetic patients was 1.3% (95% CI: 0.6% to 2.8%; I²=99.126%; P<0.001).
Conclusion: Based on the main findings, SSIs continue to be a significant complication of knee arthroplasty, with an incidence of 1.1% to 2.6%. Male gender and diabetes mellitus were associated with an augmented probability of SSIs following knee arthroplasty.
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| format | Article |
| id | doaj-art-0044dee829e847ba9b8a75f0cd941d6a |
| institution | Kabale University |
| issn | 2645-4904 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Archives of Academic Emergency Medicine |
| spelling | doaj-art-0044dee829e847ba9b8a75f0cd941d6a2025-02-11T20:47:56ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042025-01-0113110.22037/aaemj.v13i1.2543Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis Ayub Bagheri Alireza Sharifi NiknafsBahar FarhadiSeyed Amirhossein MazhariParnia KarimianNafiseh Hekmati PourHamid HojjatiIman NosratabadiAzadeh Emami Reza Salehi0Department of Anesthesiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Introduction: Surgical site infection (SSI) constitutes a substantial complication after knee arthroplasty, contributing to notable morbidity. This study aimed to review the existing literature on the incidence and risk factors of SSI following knee arthroplasty. Methods: A systematic search was undertaken across various international electronic databases, including Scopus, PubMed, Web of Science, and Persian electronic databases such as Iranmedex and the Scientific Information Database. The search strategy involved the use of keywords derived from Medical Subject Headings, such as “incidence”, “Surgical wound infection”, “Surgical site infection”, and “Arthroplasty”, covering records from the earliest available up to March 17, 2024. Results: The study incorporated a collective participant group of 1,366,494 knee arthroplasty procedures from twenty-three chosen studies. The pooled incidence rate of SSI after knee arthroplasty was 1.7% (95% confidence interval (CI): 1.1% to 2.6%; I²=99.687%; P<0.001). The Odds Ratio (OR) for the incidence of SSI in males was observed to be significantly higher than that in females (OR: 1.617; 95% CI: 1.380 to 1.894; Z=5.951; P<0.001). The pooled incidence of SSI among diabetic patients was 1.3% (95% CI: 0.6% to 2.8%; I²=99.126%; P<0.001). Conclusion: Based on the main findings, SSIs continue to be a significant complication of knee arthroplasty, with an incidence of 1.1% to 2.6%. Male gender and diabetes mellitus were associated with an augmented probability of SSIs following knee arthroplasty. https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2543PrevalenceSurgical Wound InfectionSurgical Site InfectionArthroplastyMeta-analysis |
| spellingShingle | Ayub Bagheri Alireza Sharifi Niknafs Bahar Farhadi Seyed Amirhossein Mazhari Parnia Karimian Nafiseh Hekmati Pour Hamid Hojjati Iman Nosratabadi Azadeh Emami Reza Salehi Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis Archives of Academic Emergency Medicine Prevalence Surgical Wound Infection Surgical Site Infection Arthroplasty Meta-analysis |
| title | Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis |
| title_full | Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis |
| title_fullStr | Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis |
| title_full_unstemmed | Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis |
| title_short | Incidence and Risk Factors of Surgical Site Infection After Knee Arthroplasty; a Systematic Review and Meta-Analysis |
| title_sort | incidence and risk factors of surgical site infection after knee arthroplasty a systematic review and meta analysis |
| topic | Prevalence Surgical Wound Infection Surgical Site Infection Arthroplasty Meta-analysis |
| url | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2543 |
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