SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE
The article discusses the data on the functioning of Na+,K+,2Cl– cotransport – the carrier providing electroneutral symport of sodium, potassium and chloride, as well as molecular mechanisms of the regulation and physiological significance of this carrier. We analyzed the novel data on involvement o...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2014-12-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/175 |
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| _version_ | 1849689272348573696 |
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| author | S. N. Orlov S. V. Koltsova Ya. D. Anfinogenova L. V. Kapilevich S. N. Gusakova L. V. Smagliy M. B. Baskakov M. A. Medvedev |
| author_facet | S. N. Orlov S. V. Koltsova Ya. D. Anfinogenova L. V. Kapilevich S. N. Gusakova L. V. Smagliy M. B. Baskakov M. A. Medvedev |
| author_sort | S. N. Orlov |
| collection | DOAJ |
| description | The article discusses the data on the functioning of Na+,K+,2Cl– cotransport – the carrier providing electroneutral symport of sodium, potassium and chloride, as well as molecular mechanisms of the regulation and physiological significance of this carrier. We analyzed the novel data on involvement of ubiquitous isoform of Na+,K+,2Cl–cotransporter (NKCC1) in regulation of vascular smooth muscle contraction, and role of this carrier in the regulation of cell volume and intracellular chloride concentration. |
| format | Article |
| id | doaj-art-002d85d8b9cb4a899ffde7b032e01075 |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2014-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-002d85d8b9cb4a899ffde7b032e010752025-08-20T03:21:42ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842014-12-0113616517310.20538/1682-0363-2014-6-165-173173SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONES. N. Orlov0S. V. Koltsova1Ya. D. Anfinogenova2L. V. Kapilevich3S. N. Gusakova4L. V. Smagliy5M. B. Baskakov6M. A. Medvedev7M.V. Lomonosov Moscow State University, Moscow; National Research Tomsk State University, TomskM.V. Lomonosov Moscow State University, MoscowSiberian Medical UniversityNational Research Tomsk State University, Tomsk; Siberian Medical UniversitySiberian Medical UniversitySiberian Medical UniversitySiberian Medical UniversitySiberian Medical UniversityThe article discusses the data on the functioning of Na+,K+,2Cl– cotransport – the carrier providing electroneutral symport of sodium, potassium and chloride, as well as molecular mechanisms of the regulation and physiological significance of this carrier. We analyzed the novel data on involvement of ubiquitous isoform of Na+,K+,2Cl–cotransporter (NKCC1) in regulation of vascular smooth muscle contraction, and role of this carrier in the regulation of cell volume and intracellular chloride concentration.https://bulletin.ssmu.ru/jour/article/view/175na+k+2cl– cotransportarterial hypertension |
| spellingShingle | S. N. Orlov S. V. Koltsova Ya. D. Anfinogenova L. V. Kapilevich S. N. Gusakova L. V. Smagliy M. B. Baskakov M. A. Medvedev SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE Бюллетень сибирской медицины na+ k+ 2cl– cotransport arterial hypertension |
| title | SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE |
| title_full | SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE |
| title_fullStr | SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE |
| title_full_unstemmed | SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE |
| title_short | SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE |
| title_sort | sodium potassium chloride cotransport in the regulation of vascular myogenic tone |
| topic | na+ k+ 2cl– cotransport arterial hypertension |
| url | https://bulletin.ssmu.ru/jour/article/view/175 |
| work_keys_str_mv | AT snorlov sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone AT svkoltsova sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone AT yadanfinogenova sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone AT lvkapilevich sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone AT sngusakova sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone AT lvsmagliy sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone AT mbbaskakov sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone AT mamedvedev sodiumpotassiumchloridecotransportintheregulationofvascularmyogenictone |