Conserved lipid-facing basic residues promote the insertion of the porin OmpC into the E. coli outer membrane

ABSTRACT Almost all integral membrane proteins that reside in the outer membrane (OM) of gram-negative bacteria contain a closed amphipathic β sheet (“β barrel”) that serves as a membrane anchor. The membrane integration of β barrel structures is catalyzed by a highly conserved heterooligomer called...

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Bibliographic Details
Main Authors: Janine H. Peterson, Lixinhao Yang, James C. Gumbart, Harris D. Bernstein
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.03319-24
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