Increased cell killing effect in neutron capture enhanced proton beam therapy

Increased cell killing effect in neutron capture enhanced proton beam therapy

Abstract Thermal neutrons generated in the body during proton beam therapy (PBT) can be used to cause boron neutron capture reactions and have recently been proposed as neutron capture enhanced PBT (NCEPBT). However, the cell killing effect of NCEPBT remains underexplored. Here, we show an increase...

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Bibliographic Details
Main Authors: Shintaro Shiba, Takahiro Shimo, Masashi Yamanaka, Takayuki Yagihashi, Makoto Sakai, Tatsuya Ohno, Koichi Tokuuye, Motoko Omura
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Proton beam therapy
Neutron capture enhanced proton beam therapy
Radiotherapy
Boron neutron capture reaction
Boron neutron capture therapy
Boronophenylalanine
Online Access:https://doi.org/10.1038/s41598-024-79045-3
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