Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation

SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or B...

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Main Authors: A. L. M. J. van der Knijff-van Dortmont, M. Dirckx, J. J. Duvekot, J. W. Roos-Hesselink, A. Gonzalez Candel, C. D. van der Marel, G. P. Scoones, V. F. R. Adriaens, I. J. J. Dons-Sinke
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2016/9278409
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author A. L. M. J. van der Knijff-van Dortmont
M. Dirckx
J. J. Duvekot
J. W. Roos-Hesselink
A. Gonzalez Candel
C. D. van der Marel
G. P. Scoones
V. F. R. Adriaens
I. J. J. Dons-Sinke
author_facet A. L. M. J. van der Knijff-van Dortmont
M. Dirckx
J. J. Duvekot
J. W. Roos-Hesselink
A. Gonzalez Candel
C. D. van der Marel
G. P. Scoones
V. F. R. Adriaens
I. J. J. Dons-Sinke
author_sort A. L. M. J. van der Knijff-van Dortmont
collection DOAJ
description SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour.
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institution Kabale University
issn 2090-6382
2090-6390
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publishDate 2016-01-01
publisher Wiley
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series Case Reports in Anesthesiology
spelling doaj-art-0014d5b391b64673a62949497dad08772025-02-03T01:24:27ZengWileyCase Reports in Anesthesiology2090-63822090-63902016-01-01201610.1155/2016/92784099278409Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene MutationA. L. M. J. van der Knijff-van Dortmont0M. Dirckx1J. J. Duvekot2J. W. Roos-Hesselink3A. Gonzalez Candel4C. D. van der Marel5G. P. Scoones6V. F. R. Adriaens7I. J. J. Dons-Sinke8Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Obstetrics and Gynaecology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Cardiology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, NetherlandsDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, NetherlandsSCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour.http://dx.doi.org/10.1155/2016/9278409
spellingShingle A. L. M. J. van der Knijff-van Dortmont
M. Dirckx
J. J. Duvekot
J. W. Roos-Hesselink
A. Gonzalez Candel
C. D. van der Marel
G. P. Scoones
V. F. R. Adriaens
I. J. J. Dons-Sinke
Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
Case Reports in Anesthesiology
title Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
title_full Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
title_fullStr Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
title_full_unstemmed Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
title_short Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
title_sort epidural analgesia with ropivacaine during labour in a patient with a scn5a gene mutation
url http://dx.doi.org/10.1155/2016/9278409
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