Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors

Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors

Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of hematologic malignancies, achieving remarkable clinical success with FDA-approved therapies targeting CD19 and BCMA. However, the extension of these successes to solid tumors remains limited due to several intrinsic c...

Full description

Saved in:
Bibliographic Details
Main Authors: Safwaan H. Khan, Yeonjoo Choi, Mysore Veena, John K. Lee, Daniel Sanghoon Shin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
CAR T cell
solid tumors
immunotherapy
cancer
structure
targets
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1489827/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items