Unlocking the therapeutic potential of ATR inhibitors: Advances, challenges, and opportunities in cancer therapy by Tejaswini P Reddy, Timothy A. Yap

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Phase 1 first-in-human dose-escalation study of IMSA101, a novel cyclic di-nucleotide STING agonist, for patients with advanced solid tumor malignancies by Syed Kazmi, Lijun Sun, Justin Moser, Angela Alistar, Timothy A Yap, Edward Garmey, Teresa Mooneyham, Peter Vu, Jay Jacoby, Deva Mahalingam

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IOLite: phase 1b trial of doublet/triplet combinations of dostarlimab with niraparib, carboplatin–paclitaxel, with or without bevacizumab in patients with advanced cancer by Wei Guo, Manish R Patel, Nashat Gabrail, Jordi Rodon, Erika Hamilton, Timothy A Yap, Meghan Duncan, Alberto Bessudo, Jasgit Sachdev, Lena Evilevitch, Sujatha Kumar, Sharon Lu, Bruce J Dezube

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Exceptional response to the ATR inhibitor, camonsertib, in a patient with ALT+ metastatic melanoma by Natalie Y. L. Ngoi, Ian M. Silverman, Adrienne Johnson, Chenfeng Meng, Joseph D. Schonhoft, Michal Zimmermann, Danielle Ulanet, Hyeyeon Kim, Carlos Torrado, Carolina Salguero, Christian Valladolid Brown, Jordi Rodon, Victoria Rimkunas, Maria Koehler, Timothy A. Yap

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Multi-purpose utility of circulating plasma DNA testing in patients with advanced cancers. by Geraldine Perkins, Timothy A Yap, Lorna Pope, Amy M Cassidy, Juliet P Dukes, Ruth Riisnaes, Christophe Massard, Philippe A Cassier, Susana Miranda, Jeremy Clark, Katie A Denholm, Khin Thway, David Gonzalez De Castro, Gerhardt Attard, L Rhoda Molife, Stan B Kaye, Udai Banerji, Johann S de Bono

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Lefitolimod in Combination with Ipilimumab in Patients with Advanced Solid Tumors: A Phase I Trial by Mirella Nardo, Mohamed A. Gouda, Matthew J. Reilley, Amadeo B. Biter, Joann Lim, Stacie A. Bean, Ly M. Nguyen, Priya R. Bhosale, Casey R. Ager, Coline A. Couillault, Sarina A. Piha-Paul, Siqing Fu, Apostolia M. Tsimberidou, Timothy A. Yap, Aung Naing, Jordi Rodon, Vivek Subbiah, Daniel D. Karp, Michael A. Curran, David S. Hong

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Early tolerance and late persistence as alternative drug responses in cancer by Simona Punzi, Davide Cittaro, Guido Gatti, Gemma Crupi, Oronza A. Botrugno, Antonino Alex Cartalemi, Alon Gutfreund, Caterina Oneto, Valentina Giansanti, Chiara Battistini, Giovanni Santacatterina, Lucrezia Patruno, Ilaria Villanti, Martina Palumbo, Daniel J. Laverty, Francesca Giannese, Alex Graudenzi, Giulio Caravagna, Marco Antoniotti, Zachary Nagel, Ugo Cavallaro, Luisa Lanfrancone, Timothy A. Yap, Giulio Draetta, Nathalie Balaban, Giovanni Tonon

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