Combination of tauroursodeoxycholic acid, co-enzyme Q10 and creatine demonstrates additive neuroprotective effects in in-vitro models of Parkinson’s disease by Alexander Shtilbans, Alexander Shtilbans, Wolfgang E. Reintsch, Valerio E. C. Piscopo, Andrea I. Krahn, Thomas M. Durcan

Get full text

Multiplex Immunofluorescent Batch Labeling of Marmoset Brain Sections by Daryan Chitsaz, Christopher D. Rowley, Nonthué A. Uccelli, Sarah Lefebvre, Andrea I. Krahn, Wolfgang E. Reintsch, Thomas M. Durcan, Christine L. Tardif, Timothy E. Kennedy

Get full text

14-3-3ζ allows for adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation by Sabri A. Rial, Zhipeng You, Alexis Vivoli, Fédéric Paré, Daphné Sean, Amal AlKhoury, Geneviève Lavoie, Mete Civelek, Aida Martinez-Sanchez, Philippe P. Roux, Thomas M. Durcan, Gareth E. Lim

Get full text

Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924 by Sarah Lépine, Gilles Maussion, Alexandria Schneider, Angela Nauleau-Javaudin, María José Castellanos-Montiel, Georgina Jiménez Ambriz, Dan Spiegelman, Narges Abdian, Anna Krystina Franco-Flores, Ghazal Haghi, Lale Gursu, Michael R. Fiorini, Allison A. Dilliott, Sali M. K. Farhan, Mathilde Chaineau, Thomas M. Durcan

Get full text

Female mice exhibit resistance to disease progression despite early pathology in a transgenic mouse model inoculated with alpha-synuclein fibrils by Stephanie Tullo, Janice Sung Hyun Park, Daniel Gallino, Megan Park, Kristie Mar, Vladislav Novikov, Rodrigo Sandoval Contreras, Raihaan Patel, Esther del Cid-Pellitero, Edward A. Fon, Wen Luo, Irina Shlaifer, Thomas M. Durcan, Marco A. M. Prado, Vania F. Prado, Gabriel A. Devenyi, M. Mallar Chakravarty

Get full text

Correction: The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons by Jace Jones-Tabah, Kathy He, Nathan Karpilovsky, Konstantin Senkevich, Ghislaine Deyab, Isabella Pietrantonio, Thomas Goiran, Yuting Cousineau, Daria Nikanorova, Taylor Goldsmith, Esther del Cid Pellitero, Carol X.-Q. Chen, Wen Luo, Zhipeng You, Narges Abdian, Jamil Ahmad, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Stanley Fahn, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Lior Greenbaum, Sharon Hassin-Baer, Roy N. Alcalay, Austen Milnerwood, Thomas M. Durcan, Ziv Gan-Or, Edward A. Fon

Get full text

The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons by Jace Jones-Tabah, Kathy He, Nathan Karpilovsky, Konstantin Senkevich, Ghislaine Deyab, Isabella Pietrantonio, Thomas Goiran, Yuting Cousineau, Daria Nikanorova, Taylor Goldsmith, Esther del Cid Pellitero, Carol X.-Q. Chen, Wen Luo, Zhipeng You, Narges Abdian, Jamil Ahmad, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Stanley Fahn, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Lior Greenbaum, Sharon Hassin-Baer, Roy N. Alcalay, Austen Milnerwood, Thomas M. Durcan, Ziv Gan-Or, Edward A. Fon

Get full text