Nasal valve obstruction: a comprehensive analysis of the current literature and proposal of a management algorithm by Francesca Pirola, Raymond Kim, Richard Douglas

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P112: Phenotype prediction using cell-free DNA fragmentation as a predictor of clinical severity in neurofibromatosis type 1 (NF1) by Maha Tageldein, Derek Wong, Julia Sobotka, Carolina Barnett-Tapia, Hamid Sadeghian, Emily Thain, Katharine Cardiff, Particia Parkin, Raymond Kim, Trevor Pugh

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O10: Early detection of BRCA1/2-associated cancers through multi-modal cell-free DNA analysis by Erik Ensminger, Ping Luo, Derek Wong, Julia Sobotka, Leslie E. Oldfield, Kirsten Farncombe, Adriana Aguilar-Mahecha, Jenna Eagles, Helia Purnaghshband, Stephanie Pederson, Lawrence Heisler, Bernard Lam, Mark Basik, Trevor Pugh, Raymond Kim

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P124: Liquid biopsy for early cancer detection in children and adults with hereditary cancer syndromes across Canada by Julia Sobotka, Lesa Dawson, Angela Hyde, Mark Basik, Stephanie Wong, Holly Etchegary, Marc Clausen, Teresa Tiano, Alicia Tone, Chiquita Hessels, Leslie Born, David Malkin, Andra Doria, Aly Karsan, Lynette Penney, Kirsten Farncombe, Patrick Veit-Haibach, Kasmintan Schrader, Yvonne Bombard, Raymond Kim, Trevor Pugh

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P298: Decoding ambiguity: Evaluating the psychological harms and utility of returning cancer variants of uncertain significance by Jordan Sam, Chloe Mighton, Emma Reble, Salma Shickh, Marc Clausen, Rita Kodida, Daena Hirjikaka, Sonya Grewal, Seema Panchal, Melyssa Aronson, Kara Semotiuk, Susan Armel, Tracy Graham, Nicole Forster, José-Mario Capo-Chichi, Elena Greenfeld, Abdul Noor, Iris Cohn, Chantal Morel, Christine Elser, Andrea Eisen, June Carroll, Emily Glogowksi, Kasmintan Schrader, Jordan Lerner-Ellis, Raymond Kim, Kevin Thorpe, Yvonne Bombard

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P136: Data model and portal development supporting centralization of genetic information in a provincial research network by Elif Tuzlali, Linda Xiang, Lauren Hughes, Brandon Chan, Patrick Dos Santos, Rakesh Mistry, Ann Catton, Jon Eubank, Samantha Rich, Harriet Feilotter, Jordan Lerner-Ellis, Kenneth Craddock, Anjelica Hodgson, Andrew Lingard, Vasily Giannakeas, Melissa Cable-Cibula, Christopher Deutschman, Katie Lark, Meredith McLaren, Kathy Chun, Laila Schenkel, Amanda Smith, Andrea Vaags, Hong Wang, Michelle Brazas, Lincoln Stein, Raymond Kim, Melanie Courtot

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P686: Opportunistic screening for broad range of clinically relevant secondary findings: Outcomes of exome analysis in the Incidental Genomics RCT by Chloe Mighton, Emma Reble, Jordan Sam, Rita Kodida, Salma Shickh, Marc Clausen, Daena Hirjikaka, Sonya Grewal, Seema Panchal, Carolyn Piccinin, Melyssa Aronson, Susan Randall Armel, Larissa Peck, Tracy Graham, Yael Silberman, Thomas Ward, José-Mario Capo-Chichi, Elena Greenfeld, Abdul Noor, Iris Cohn, Chantal Morel, Christine Elser, Andrea Eisen, Emily Glogowski, Kasmintan Schrader, Raymond Kim, Kelvin Chan, Kevin Thorpe, Jordan Lerner-Ellis, Yvonne Bombard

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