Alveolar epithelial type 2 cell specific loss of IGFBP2 activates inflammation in COVID-19 by Valentina Pujadas, Chiahsuan Chin, Narendra V. Sankpal, James Buhrmaster, Ashwini Arjuna, Rajat Walia, Michael A. Smith, Oliver Eickelberg, Ross M. Bremner, Thalachallour Mohanakumar, Angara Sureshbabu

Get full text

Fludarabine attenuates inflammation and dysregulated autophagy in alveolar macrophages via inhibition of STAT1/IRF1 pathway by Jooyeon Lee, Jeong-Ran Park, Hanbyeol Lee, Seok-Ho Hong, Woo Jin Kim, Oliver Eickelberg, Sung-Min Park, Semin Ryu, Sung Joon Cho, Seung-Jin Kim, Se-Ran Yang

Get full text

FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis by Hamza M Al‐Tamari, Swati Dabral, Anja Schmall, Pouya Sarvari, Clemens Ruppert, Jihye Paik, Ronald A DePinho, Friedrich Grimminger, Oliver Eickelberg, Andreas Guenther, Werner Seeger, Rajkumar Savai, Soni S Pullamsetti

Get full text

Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease by Prajakta Oak, Tina Pritzke, Isabella Thiel, Markus Koschlig, Daphne S Mous, Anita Windhorst, Noopur Jain, Oliver Eickelberg, Kai Foerster, Andreas Schulze, Wolfgang Goepel, Tobias Reicherzer, Harald Ehrhardt, Robbert J Rottier, Peter Ahnert, Ludwig Gortner, Tushar J Desai, Anne Hilgendorff

Get full text

Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers by Christoph H Mayr, Lukas M Simon, Gabriela Leuschner, Meshal Ansari, Janine Schniering, Philipp E Geyer, Ilias Angelidis, Maximilian Strunz, Pawandeep Singh, Nikolaus Kneidinger, Frank Reichenberger, Edith Silbernagel, Stephan Böhm, Heiko Adler, Michael Lindner, Britta Maurer, Anne Hilgendorff, Antje Prasse, Jürgen Behr, Matthias Mann, Oliver Eickelberg, Fabian J Theis, Herbert B Schiller

Get full text

Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease by Jie Jia, Thomas M Conlon, Rim SJ Sarker, Demet Taşdemir, Natalia F Smirnova, Barkha Srivastava, Stijn E Verleden, Gizem Güneş, Xiao Wu, Cornelia Prehn, Jiaqi Gao, Katharina Heinzelmann, Jutta Lintelmann, Martin Irmler, Stefan Pfeiffer, Michael Schloter, Ralf Zimmermann, Martin Hrabé de Angelis, Johannes Beckers, Jerzy Adamski, Hasan Bayram, Oliver Eickelberg, Ali Önder Yildirim

Get full text

Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models by Darcy Elizabeth Wagner, Hani N. Alsafadi, Nilay Mitash, Aurelien Justet, Qianjiang Hu, Ricardo Pineda, Claudia Staab-Weijnitz, Martina Korfei, Nika Gvazava, Kristin Wannemo, Ugochi Onwuka, Molly Mozurak, Adriana Estrada-Bernal, Juan Cala-Garcia, Katrin Mutze, Rita Costa, Deniz Bölükbas, John Stegmayr, Wioletta Skronska-Wasek, Stephan Klee, Chiharu Ota, Hoeke A. Baarsma, Jingtao Wang, John Sembrat, Anne Hilgendorff, Jun Ding, Andreas Günther, Rachel Chambers, Ivan Rosas, Stijn de Langhe, Naftali Kaminski, Mareike Lehmann, Oliver Eickelberg, Melanie Königshoff

Get full text

Preclinical concept studies showing advantage of an inhaled anti-CTGF/CCN2 protein for pulmonary fibrosis treatment by Vanessa Neiens, Eva-Maria Hansbauer, Thomas J. Jaquin, Janet K. Peper-Gabriel, Poornima Mahavadi, Mark E. Snyder, Maximilian J. Grill, Cornelia Wurzenberger, Antonio Konitsiotis, Adriana Estrada-Bernal, Kristina Heinig, Athanasios Fysikopoulos, Nicolas Schwenck, Stefan Grüner, Denis Bartoschek, Theresia Mosebach, Sandra Kerstan, Joe Wrennall, Marleen Richter, Kentaro Noda, Konrad Hoetzenecker, Janette K. Burgess, Robert Tarran, Claudia Wurzenberger, Karl-Robert Wichmann, Jonas Biehler, Kei W. Müller, Andreas Guenther, Oliver Eickelberg, Mary F. Fitzgerald, Shane A. Olwill, Gabriele Matschiner, Marina Pavlidou

Get full text