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N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models. by Christopher T Esapa, Fadil M Hannan, Valerie N Babinsky, Paul Potter, Gethin P Thomas, Peter I Croucher, Matthew A Brown, Steve D M Brown, Roger D Cox, Rajesh V Thakker
Published 2015-01-01Get full text
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Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease. by Patrick Danoy, Karena Pryce, Johanna Hadler, Linda A Bradbury, Claire Farrar, Jennifer Pointon, Australo-Anglo-American Spondyloarthritis Consortium, Michael Ward, Michael Weisman, John D Reveille, B Paul Wordsworth, Millicent A Stone, Spondyloarthritis Research Consortium of Canada, Walter P Maksymowych, Proton Rahman, Dafna Gladman, Robert D Inman, Matthew A Brown
Published 2010-12-01Get full text
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Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. by Adaikalavan Ramasamy, Mikko Kuokkanen, Sailaja Vedantam, Zofia K Gajdos, Alexessander Couto Alves, Helen N Lyon, Manuel A R Ferreira, David P Strachan, Jing Hua Zhao, Michael J Abramson, Matthew A Brown, Lachlan Coin, Shyamali C Dharmage, David L Duffy, Tari Haahtela, Andrew C Heath, Christer Janson, Mika Kähönen, Kay-Tee Khaw, Jaana Laitinen, Peter Le Souef, Terho Lehtimäki, Australian Asthma Genetics Consortium Collaborators, Pamela A F Madden, Guy B Marks, Nicholas G Martin, Melanie C Matheson, Cameron D Palmer, Aarno Palotie, Anneli Pouta, Colin F Robertson, Jorma Viikari, Elisabeth Widen, Matthias Wjst, Deborah L Jarvis, Grant W Montgomery, Philip J Thompson, Nick Wareham, Johan Eriksson, Pekka Jousilahti, Tarja Laitinen, Juha Pekkanen, Olli T Raitakari, George T O'Connor, Veikko Salomaa, Marjo-Riitta Jarvelin, Joel N Hirschhorn
Published 2012-01-01Get full text
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WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. by Hou-Feng Zheng, Jon H Tobias, Emma Duncan, David M Evans, Joel Eriksson, Lavinia Paternoster, Laura M Yerges-Armstrong, Terho Lehtimäki, Ulrica Bergström, Mika Kähönen, Paul J Leo, Olli Raitakari, Marika Laaksonen, Geoffrey C Nicholson, Jorma Viikari, Martin Ladouceur, Leo-Pekka Lyytikäinen, Carolina Medina-Gomez, Fernando Rivadeneira, Richard L Prince, Harri Sievanen, William D Leslie, Dan Mellström, John A Eisman, Sofia Movérare-Skrtic, David Goltzman, David A Hanley, Graeme Jones, Beate St Pourcain, Yongjun Xiao, Nicholas J Timpson, George Davey Smith, Ian R Reid, Susan M Ring, Philip N Sambrook, Magnus Karlsson, Elaine M Dennison, John P Kemp, Patrick Danoy, Adrian Sayers, Scott G Wilson, Maria Nethander, Eugene McCloskey, Liesbeth Vandenput, Richard Eastell, Jeff Liu, Tim Spector, Braxton D Mitchell, Elizabeth A Streeten, Robert Brommage, Ulrika Pettersson-Kymmer, Matthew A Brown, Claes Ohlsson, J Brent Richards, Mattias Lorentzon
Published 2012-07-01Get full text
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