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The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levels by Daniela Mennerich, Yashwanth Ashok, Carlos Vela-Rodríguez, Heli I. Hentilä, Melanie Rall-Scharpf, Lisa Wiesmüller, Renata Prunskaite-Hyyryläinen, Lari Lehtiö, Thomas Kietzmann
Published 2025-08-01Get full text
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Identification of a series of pyrrolo-pyrimidine-based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication by Jessica J. Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff, Lavinia M. Sherrill, Iain Colquhoun, Gabrielle Cadoux, Devyn Thorne, Johan Pääkkönen, Nathaniel F. Schemmel, Joseph O’Connor, Pradtahna Saenjamsai, Mei Feng, Srivatsan Parthasarathy, Michael J. Hageman, David K. Johnson, Anuradha Roy, Lari Lehtiö, Dana V. Ferraris, Anthony R. Fehr
Published 2025-06-01Get full text
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