Preclinical investigations and a first-in-human phase I trial of M4112, the first dual inhibitor of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase 2, in patients with... by Sen Zhang, Jacques Moisan, Aung Naing, Kyriakos P Papadopoulos, Elizabeth Hussey, Joseph P Eder, Sarina A Piha-Paul, Claude Gimmi, Vera Hildebrand, Vinayak Hosagrahara, Christina Habermehl

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First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours by Michael Smith, Aung Naing, Todd Bauer, Kyriakos P Papadopoulos, Osama Rahma, Elena Garralda, Glenn J Hanna, Michael J Pishvaian, Xuejun Chen, Sven Gogov, Omar Saavedra, Howard Kallender, LuLu Cheng, Emil Kuriakose

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Safety and efficacy of AMG 820, an anti-colony-stimulating factor 1 receptor antibody, in combination with pembrolizumab in adults with advanced solid tumors by Jeanne Tie, Dirk Jäger, Victor Moreno, Dirk Nagorsen, Gloria Juan, Kyriakos P Papadopoulos, Anthony J Olszanski, Erik Rasmussen, Nehal Lakhani, Albiruni RA Razak, James M Cleary, Michael Boyer, Emiliano Calvo Aller, William Edenfield, R Donald Harvey, Annemie Rutten, Manish A Shah, David P Ryan, Hansen Wong, Neelesh Soman, Marie-Anne Damiette Smit

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