John R. Yates
John R. Yates III is an American chemist and Ernest W. Hahn Professor in the Departments of Molecular Medicine and Neurobiology at The Scripps Research Institute in La Jolla, California. He is currently editor-in-chief of the Journal of Proteome Research. He appeared on list of 2022, 2023 and 2024 Highly Cited Researchers, making him among the top one percent of most cited researchers in the world.His work is focused on developing tools and in proteomics and he specializes in mass spectrometry. He is best known for the development of the Sequest algorithm for automated peptide sequencing and Multidimensional Protein Identification Technology (MudPIT) and data-independent acquisition. His lab is known for its contribution to methods to identify structural changes in proteins in living cells as well as method to identify N-glycan processing and occupancy using mass spectrometry such as covalent protein painting, and DeGlyPHER (Deglycosylation-dependent Glycan/Proteomic Heterogeneity Evaluation Report). His laboratory has made important contributions to understanding the biochemical mechanisms behind the failure of △F508 cystic fibrosis ion transport regulator to mature. Provided by Wikipedia
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Mass Spectrometry as an Emerging Tool for Systems Biology by John R. Yates
Published 2004-06-01Get full text
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Mitotic spindle proteomics in Chinese hamster ovary cells. by Mary Kate Bonner, Daniel S Poole, Tao Xu, Ali Sarkeshik, John R Yates, Ahna R Skop
Published 2011-01-01Get full text
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Global analysis of posttranslational protein arginylation. by Catherine C L Wong, Tao Xu, Reena Rai, Aaron O Bailey, John R Yates, Yuri I Wolf, Henry Zebroski, Anna Kashina
Published 2007-10-01Get full text
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Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests. by Judith Zich, Karen May, Konstantinos Paraskevopoulos, Onur Sen, Heather M Syred, Sjaak van der Sar, Hitesh Patel, James J Moresco, Ali Sarkeshik, John R Yates, Juri Rappsilber, Kevin G Hardwick
Published 2016-02-01Get full text
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The GAGA factor regulatory network: Identification of GAGA factor associated proteins. by Dmitry Lomaev, Anna Mikhailova, Maksim Erokhin, Alexander V Shaposhnikov, James J Moresco, Tatiana Blokhina, Daniel Wolle, Tsutomu Aoki, Vladimir Ryabykh, John R Yates, Yulii V Shidlovskii, Pavel Georgiev, Paul Schedl, Darya Chetverina
Published 2017-01-01Get full text
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The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair. by Hailong Wang, Linda Z Shi, Catherine C L Wong, Xuemei Han, Patty Yi-Hwa Hwang, Lan N Truong, Qingyuan Zhu, Zhengping Shao, David J Chen, Michael W Berns, John R Yates, Longchuan Chen, Xiaohua Wu
Published 2013-01-01Get full text
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Insulin secretion deficits in a Prader-Willi syndrome β-cell model are associated with a concerted downregulation of multiple endoplasmic reticulum chaperones. by Erik A Koppes, Marie A Johnson, James J Moresco, Patrizia Luppi, Dale W Lewis, Donna B Stolz, Jolene K Diedrich, John R Yates, Ronald C Wek, Simon C Watkins, Susanne M Gollin, Hyun Jung Park, Peter Drain, Robert D Nicholls
Published 2023-04-01Get full text
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Intercepting IRE1 kinase‐FMRP signaling prevents atherosclerosis progression by Zehra Yildirim, Sabyasachi Baboo, Syed M Hamid, Asli E Dogan, Ozlem Tufanli, Sabrina Robichaud, Christina Emerton, Jolene K Diedrich, Hasan Vatandaslar, Fotis Nikolos, Yanghong Gu, Takao Iwawaki, Elizabeth Tarling, Mireille Ouimet, David L Nelson, John R Yates, Peter Walter, Ebru Erbay
Published 2022-02-01Get full text
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Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis by Shridhar Bale, Elena Gustchina, Javier Guenaga, Victor Ayala, Wen-Hsin Lee, Gabriel Ozorowski, Stephen Whitney, Richard Wilson, Sabyasachi Baboo, Jolene K. Diedrich, Esmeralda D. Doyle, Lauren Hudacik, Elana Ben-Akiva, Kristen A. Rodrigues, Darrell J. Irvine, John R. Yates, James C. Paulson, Andrew B. Ward, Timothy Fouts, Richard T. Wyatt
Published 2025-08-01Get full text
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Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin. by Zachary T Berndsen, Marjahan Akhtar, Mahima Thapa, Tim J Vickers, Aaron Schmitz, Jonathan L Torres, Sabyasachi Baboo, Pardeep Kumar, Nazia Khatoon, Alaullah Sheikh, Melissa Hamrick, Jolene K Diedrich, Salvador Martinez-Bartolome, Patrick T Garrett, John R Yates, Jackson S Turner, Renee M Laird, Frédéric Poly, Chad K Porter, Jeffrey Copps, Ali H Ellebedy, Andrew B Ward, James M Fleckenstein
Published 2024-09-01Get full text
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