An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo by Huiping Shuai, Jingxin Qiao, Chaemin Yoon, Guo Zhang, Yuxin Hou, Xiaoyan Xia, Lei Wang, Xinyue Deng, Yifei Wang, Qingquan Li, Lianzhao Du, Yuanchen Liu, Minmin Zhou, Hoi Ting Wong, Jiaheng Hu, Huan Liu, Bingjie Hu, Dong Wang, Jingyi Su, Yuying Pan, Yongtao Ye, Yan Chen, Zhen Fang, Ziyi Xia, Yue Chai, Jialu Shi, Yang Wang, Tianrenzheng Zhu, Honglei Zhang, Shuofeng Yuan, Jie Zhou, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Chunfu Xu, Jian Lei, Shengyong Yang, Hin Chu

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A novel, covalent broad-spectrum inhibitor targeting human coronavirus Mpro by Jing Sun, Deheng Sun, Qi Yang, Dong Wang, Jingjing Peng, Hu Guo, Xiaoyu Ding, Zhao Chen, Bin Yuan, Yan A. Ivanenkov, Jinwei Yuan, Bogdan A. Zagribelnyy, Yiyun He, Jingyi Su, Ling Wang, Jielin Tang, Zhun Li, Rong Li, Taotao Li, Xiaoyu Hu, Xing Liang, Airu Zhu, Peilan Wei, Yaya Fan, Sang Liu, Jie Zheng, Xin Guan, Alex Aliper, Minglei Yang, Dmitry S. Bezrukov, Zhanhong Xie, Victor A. Terentiev, Guilin Peng, Daniil A. Polykovskiy, Alexander S. Malyshev, Maxim N. Malkov, Qingsong Zhu, Alán Aspuru-Guzik, Xiao Ding, Xin Cai, Man Zhang, Jingxian Zhao, Nanshan Zhong, Feng Ren, Xinwen Chen, Alex Zhavoronkov, Jincun Zhao

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