Intratumoral IL12 mRNA administration activates innate and adaptive pathways in checkpoint inhibitor-resistant tumors resulting in complete responses by Jayalakshmi Lakshmipathi, Sreevidya Santha, Man Li, Yuping Qian, Simon F. Roy, Nadia Luheshi, Katerina Politi, Marcus Bosenberg, Jim Eyles, Viswanathan Muthusamy

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Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models by Brajesh P. Kaistha, Gozde Kar, Andreas Dannhorn, Amanda Watkins, Grace Opoku-Ansah, Kristina Ilieva, Stefanie Mullins, Judith Anderton, Elena Galvani, Fabien Garcon, Jean-Martin Lapointe, Lee Brown, James Hair, Tim Slidel, Nadia Luheshi, Kelli Ryan, Elizabeth Hardaker, Simon Dovedi, Rakesh Kumar, Robert W. Wilkinson, Scott A. Hammond, Jim Eyles

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Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC models by Jian Ye, Brian A Belt, Shuyang S Qin, Rachel Jewell, Laura M Calvi, Bradley N Mills, Tara G Vrooman, Carl J Johnston, Scott A Gerber, Angela L Hughson, Gary Hannon, Maggie L Lesch, Jim Eyles, Nadia Luheshi, Noah A Salama, Sidney Lesser, Sarah L Eckl, Lauren Benoodt, Edith Lord, David Linehan

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An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine release by D Gareth Rees, Yun He, Scott A Hammond, Mark Cobbold, Nicolas Giraldo, Saso Cemerski, Marina Natoli, Yiping Rong, Jonathan Fitzgerald, Kathy Mulgrew, Simon J Dovedi, Miguel Gaspar, Christopher Lloyd, Jim Eyles, Laure Castan, Sharif Rahmy, Cathryn Kelton, Martin Korade, Oisin Huhn, Anna Sigurdardottir, Kathryn Ball, Laura Dallaway, Jonathan J Taylor, Phillip M Brailey, Aleksandra Toloczko, Maria A S Broggi, Andrew Kunihiro, Sudhanshu Abhishek

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