In vivo binding and retention of CD4-specific DARPin 57.2 in macaques. by Pavel Pugach, Anders Krarup, Agegnehu Gettie, Marcelo Kuroda, James Blanchard, Michael Piatak, Jeffrey D Lifson, Alexandra Trkola, Melissa Robbiani

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Effects of treatment with suppressive combination antiretroviral drug therapy and the histone deacetylase inhibitor suberoylanilide hydroxamic acid; (SAHA) on SIV-infected Chinese... by Binhua Ling, Michael Piatak, Linda Rogers, Ann-Marie Johnson, Kasi Russell-Lodrigue, Daria J Hazuda, Jeffrey D Lifson, Ronald S Veazey

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Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir. by Taina T Immonen, Christine M Fennessey, Leslie Lipkey, Abigail Thorpe, Gregory Q Del Prete, Jeffrey D Lifson, Miles P Davenport, Brandon F Keele

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A tonsillar PolyICLC/AT-2 SIV therapeutic vaccine maintains low viremia following antiretroviral therapy cessation. by Panagiotis Vagenas, Meropi Aravantinou, Vennansha G Williams, Edith Jasny, Michael Piatak, Jeffrey D Lifson, Andres M Salazar, James L Blanchard, Agegnehu Gettie, Melissa Robbiani

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PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In Vivo. by Meropi Aravantinou, Ines Frank, Magnus Hallor, Rachel Singer, Hugo Tharinger, Jessica Kenney, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Andres Salazar, Michael Piatak, Jeffrey D Lifson, Melissa Robbiani, Nina Derby

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KIR3DL01 upregulation on gut natural killer cells in response to SIV infection of KIR- and MHC class I-defined rhesus macaques. by Moritz Ries, Matthew R Reynolds, Ksenia Bashkueva, Kristin Crosno, Saverio Capuano, Trent M Prall, Roger Wiseman, David H O'Connor, Eva G Rakasz, Hajime Uno, Jeffrey D Lifson, David T Evans

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Modifications to rhesus macaque TCR constant regions improve TCR cell surface expression. by Lori V Coren, Matthew T Trivett, Jorden L Welker, James A Thomas, Robert J Gorelick, Emek Kose, Taina T Immonen, Kelli Czarra, Christine M Fennessey, Charles M Trubey, Jeffrey D Lifson, Adrienne E Swanstrom

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ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge. by Michael D Alpert, Jackson D Harvey, W Anderson Lauer, R Keith Reeves, Michael Piatak, Angela Carville, Keith G Mansfield, Jeffrey D Lifson, Wenjun Li, Ronald C Desrosiers, R Paul Johnson, David T Evans

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Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure. by Tommi A White, Alberto Bartesaghi, Mario J Borgnia, Joel R Meyerson, M Jason V de la Cruz, Julian W Bess, Rachna Nandwani, James A Hoxie, Jeffrey D Lifson, Jacqueline L S Milne, Sriram Subramaniam

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Deep analysis of CD4 T cells in the rhesus CNS during SIV infection. by Sonny R Elizaldi, Anil Verma, Zhong-Min Ma, Sean Ott, Dhivyaa Rajasundaram, Chase E Hawes, Yashavanth Shaan Lakshmanappa, Mackenzie L Cottrell, Angela D M Kashuba, Zandrea Ambrose, Jeffrey D Lifson, John H Morrison, Smita S Iyer

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Location and dynamics of the immunodominant CD8 T cell response to SIVΔnef immunization and SIVmac251 vaginal challenge. by Arun K Sasikala-Appukuttan, Hyeon O Kim, Nikilyn J Kinzel, Jung Joo Hong, Anthony J Smith, Reece Wagstaff, Cavan Reilly, Michael Piatak, Jeffrey D Lifson, R Keith Reeves, R Paul Johnson, Ashley T Haase, Pamela J Skinner

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Combining a rhesus cytomegalovirus/SIV vaccine with a neutralizing antibody to protect against SIV challenges in rhesus macaques by Jessica Coppola, Mara Parren, Raiza Bastidas, Karen Saye, Jacqueline Malvin, Joseph G. Jardine, Roxanne M. Gilbride, Sohita Ojha, Shana Feltham, David Morrow, Aaron Barber-Axthelm, Rachele Bochart, Randy Fast, Kelli Oswald, Rebecca Shoemaker, Jeffrey D. Lifson, Louis J. Picker, Dennis R. Burton, Scott G. Hansen

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A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants. by Patrick Barnable, Giulia Calenda, Louise Ouattara, Agegnehu Gettie, James Blanchard, Ninochka Jean-Pierre, Larisa Kizima, Aixa Rodríguez, Ciby Abraham, Radhika Menon, Samantha Seidor, Michael L Cooney, Kevin D Roberts, Rhoda Sperling, Michael Piatak, Jeffrey D Lifson, Jose A Fernandez-Romero, Thomas M Zydowsky, Melissa Robbiani, Natalia Teleshova

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Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques. by Mayla Hsu, Brandon F Keele, Meropi Aravantinou, Noa Krawczyk, Samantha Seidor, Ciby J Abraham, Shimin Zhang, Aixa Rodriguez, Larisa Kizima, Nina Derby, Ninochka Jean-Pierre, Olga Mizenina, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael J Piatak, Jeffrey D Lifson, José A Fernández-Romero, Thomas M Zydowsky, Melissa Robbiani

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Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir. by Brandon F Keele, Afam A Okoye, Christine M Fennessey, Benjamin Varco-Merth, Taina T Immonen, Emek Kose, Andrew Conchas, Mykola Pinkevych, Leslie Lipkey, Laura Newman, Agatha Macairan, Marjorie Bosche, William J Bosche, Brian Berkemeier, Randy Fast, Mike Hull, Kelli Oswald, Rebecca Shoemaker, Lorna Silipino, Robert J Gorelick, Derick Duell, Alejandra Marenco, William Brantley, Jeremy Smedley, Michael Axthelm, Miles P Davenport, Jeffrey D Lifson, Louis J Picker

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Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques. by Mauricio A Martins, Young C Shin, Lucas Gonzalez-Nieto, Aline Domingues, Martin J Gutman, Helen S Maxwell, Iris Castro, Diogo M Magnani, Michael Ricciardi, Nuria Pedreño-Lopez, Varian Bailey, Dillon Betancourt, John D Altman, Matthias Pauthner, Dennis R Burton, Benjamin von Bredow, David T Evans, Maoli Yuan, Christopher L Parks, Keisuke Ejima, David B Allison, Eva Rakasz, Glen N Barber, Saverio Capuano, Jeffrey D Lifson, Ronald C Desrosiers, David I Watkins

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Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence. by Benjamin Varco-Merth, Morgan Chaunzwa, Derick M Duell, Alejandra Marenco, William Goodwin, Rachel Dannay, Michael Nekorchuk, Danica Shao, Kathleen Busman-Sahay, Christine M Fennessey, Lorna Silipino, Michael Hull, William J Bosche, Randy Fast, Kelli Oswald, Rebecca Shoemaker, Rachele Bochart, Rhonda MacAllister, Caralyn S Labriola, Jeremy V Smedley, Michael K Axthelm, Miles P Davenport, Paul T Edlefsen, Jacob D Estes, Brandon F Keele, Jeffrey D Lifson, Sharon R Lewin, Louis J Picker, Afam A Okoye

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A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection. by Scott P Lawrence, Samra E Elser, Workineh Torben, Robert V Blair, Bapi Pahar, Pyone P Aye, Faith Schiro, Dawn Szeltner, Lara A Doyle-Meyers, Beth S Haggarty, Andrea P O Jordan, Josephine Romano, George J Leslie, Xavier Alvarez, David H O'Connor, Roger W Wiseman, Christine M Fennessey, Yuan Li, Michael Piatak, Jeffrey D Lifson, Celia C LaBranche, Andrew A Lackner, Brandon F Keele, Nicholas J Maness, Mark Marsh, James A Hoxie

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Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy. by Fredrik Barrenäs, Scott G Hansen, Lynn Law, Connor Driscoll, Richard R Green, Elise Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne Whitmore, Daniel Newhouse, Colette M Hughes, David Morrow, Kurt T Randall, Andrea N Selseth, Julia C Ford, Roxanne M Gilbride, Bryan E Randall, Emily Ainslie, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J Bosche, Michael K Axthelm, Yoshinori Fukazawa, George N Pavlakis, Barbara K Felber, Slim Fourati, Rafick-Pierre Sekaly, Jeffrey D Lifson, Jan Komorowski, Ewelina Kosmider, Danica Shao, Wenjun Song, Paul T Edlefsen, Louis J Picker, Michael Gale

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