Protocol for CRISPR-based endogenous protein tagging in mammalian cells by Yu-Xi Xiao, Jiarun Wei, Jason Moffat

Get full text

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics by Traver Hart, Kevin R Brown, Fabrice Sircoulomb, Robert Rottapel, Jason Moffat

Get full text

A method for benchmarking genetic screens reveals a predominant mitochondrial bias by Mahfuzur Rahman, Maximilian Billmann, Michael Costanzo, Michael Aregger, Amy H Y Tong, Katherine Chan, Henry N Ward, Kevin R Brown, Brenda J Andrews, Charles Boone, Jason Moffat, Chad L Myers

Get full text

Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity by Adrian Granda Farias, Brian Feng, Shahbaz Khan, Wayne Ngo, Jamie L.Y. Wu, Magali Aguilera-Uribe, Shan Grewal, Patricia Mero, Sheila K. Singh, Thomas Kislinger, Warren C.W. Chan, Jason Moffat

Get full text

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities by Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O'Brien, Brenda Andrews, Charles Boone, Jason Moffat

Get full text