Jack A. Roth
Jack Alan Roth is an American physician-scientist, thoracic surgeon, and translational cancer researcher best known for leading early clinical development of gene-based therapies for thoracic malignancies and for pioneering multidisciplinary, molecularly informed approaches to lung and esophageal cancer. He is a professor in the Department of Thoracic and Cardiovascular Surgery at the University of Texas MD Anderson Cancer Center, director of the W. M. Keck Center for Innovative Cancer Therapies, and chief of the Section of Thoracic Molecular Oncology.
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Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. by Jieru Meng, Bingbing Dai, Bingliang Fang, B Nebiyou Bekele, William G Bornmann, Duoli Sun, Zhenghong Peng, Roy S Herbst, Vassiliki Papadimitrakopoulou, John D Minna, Michael Peyton, Jack A Roth
Published 2010-11-01Get full text
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A Semantic Web management model for integrative biomedical informatics. by Helena F Deus, Romesh Stanislaus, Diogo F Veiga, Carmen Behrens, Ignacio I Wistuba, John D Minna, Harold R Garner, Stephen G Swisher, Jack A Roth, Arlene M Correa, Bradley Broom, Kevin Coombes, Allen Chang, Lynn H Vogel, Jonas S Almeida
Published 2008-08-01Get full text
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Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. by Michelle A T Hildebrandt, Ritsuko Komaki, Zhongxing Liao, Jian Gu, Joe Y Chang, Yuanqing Ye, Charles Lu, David J Stewart, John D Minna, Jack A Roth, Scott M Lippman, James D Cox, Waun Ki Hong, Margaret R Spitz, Xifeng Wu
Published 2010-08-01Get full text
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Impact of select actionable genomic alterations on efficacy of neoadjuvant immunotherapy in resectable non-small cell lung cancer by Charles Lu, Mehmet Altan, Apar Pataer, Tina Cascone, Annikka Weissferdt, Jianjun Zhang, Boris Sepesi, Ara A Vaporciyan, Marcelo V Negrao, Hai T Tran, Stephen G Swisher, John V Heymach, Don L Gibbons, Brett W Carter, Jack A Roth, Ferdinandos Skoulidis, Yasir Y Elamin, Xiuning Le, Wayne L Hofstetter, J Jack Lee, Bonnie S Glisson, Myrna C B Godoy, Garrett L Walsh, Jia Wu, Humam Kadara, George R Blumenschein, Heather Y Lin, Nicolas Zhou, William N William, Cheuk H Leung, Frank V Fossella, Anne S Tsao, Jonathan M Kurie, Lauren A Byers, Reza J Mehran, David C Rice, Luisa M Solis Soto
Published 2024-10-01Get full text
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