Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates by Longlong Zhang, Hui Wang, Mengzhao Xun, Honghai Tang, Jinghan Wang, Jun Lv, Biyun Zhu, Yuxin Chen, Daqi Wang, Shaowei Hu, Ziwen Gao, Jianping Liu, Zheng-Yi Chen, Bing Chen, Huawei Li, Yilai Shu

Get full text

PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation by Shao Wei Hu, Sohyang Jeong, Luoying Jiang, Hansol Koo, Zijing Wang, Won Hoon Choi, Biyun Zhu, Heeyoung Seok, Yi Zhou, Min Gu Kim, Dan Mu, Huixia Guo, Ziyi Zhou, Sung Ho Jung, Yingting Zhang, Ho Byung Chae, Liheng Chen, Sung-Yeon Lee, Luo Guo, Myung-Whan Suh, Yang Xiao, Moo Kyun Park, Honghai Tang, Jae-Jin Song, Xi Chen, Ai Chen, Jun Ho Lee, Sangsu Bae, Sang-Yeon Lee, Yilai Shu

Get full text