Assessment of biophysical properties of the first-in-class anti-cancer IgE antibody drug MOv18 IgE demonstrates monomeric purity and stability by Paul Considine, Panida Punnabhum, Callum G. Davidson, Georgina B. Armstrong, Michaela Kreiner, Heather J. Bax, Jitesh Chauhan, James Spicer, Debra H. Josephs, Sophia N. Karagiannis, Gavin Halbert, Zahra Rattray

Get full text

Hybrid IgE-IgG1 antibodies (IgEG): a new antibody class that combines IgE and IgG functionality by Melanie Grandits, Lais C. G. F. Palhares, Olivia Macleod, John Devlin, Oliver E. Amin, James Birtley, Leanne Partington, Tim Wilson, Elizabeth Hardaker, Sophia N. Karagiannis, Heather J. Bax, Kevin FitzGerald

Get full text

Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis

Get full text

Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction by Gabriel Osborn, Jacobo López-Abente, Rebecca Adams, Roman Laddach, Melanie Grandits, Heather J. Bax, Jitesh Chauhan, Giulia Pellizzari, Mano Nakamura, Chara Stavraka, Alicia Chenoweth, Lais C. G. F. Palhares, Theodore Evan, Jessica Hui Cheah Lim, Amanda Gross, Lenny Moise, Shashi Jatiani, Mariangela Figini, Rodolfo Bianchini, Erika Jensen-Jarolim, Sharmistha Ghosh, Ana Montes, Ahmad Sayasneh, Rebecca Kristeleit, Sophia Tsoka, James Spicer, Debra H. Josephs, Sophia N. Karagiannis

Get full text