Framingham Heart Study
The
Framingham Heart Study is a long-term, ongoing
cardiovascular cohort study of residents of the city of
Framingham,
Massachusetts. The study began in 1948 with 5,209 adult subjects from Framingham, and is now on its third generation of participants. Prior to the study almost nothing was known about the
epidemiology of hypertensive or
arteriosclerotic cardiovascular disease. Much of the now-common knowledge concerning heart disease, such as the effects of
diet,
exercise, and common medications such as
aspirin, is based on this
longitudinal study. It is a project of the
National Heart, Lung, and Blood Institute, in collaboration with (since 1971)
Boston University. Various health professionals from the hospitals and universities of
Greater Boston staff the project.
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