Integrating single cell sequencing with a spatial quantitative systems pharmacology model spQSP for personalized prediction of triple-negative breast cancer immunotherapy response by Shuming Zhang, Chang Gong, Alvaro Ruiz-Martinez, Hanwen Wang, Emily Davis-Marcisak, Atul Deshpande, Aleksander S. Popel, Elana J. Fertig

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Viral status, immune microenvironment and immunological response to checkpoint inhibitors in hepatocellular carcinoma by Hao Wang, Elizabeth Jaffee, Ludmila Danilova, James M Leatherman, Won Jin Ho, Mark Yarchoan, Su Jin Lim, Rohan Verma, Stephanie Xavier, Marcelo B Sztein, Elana J Fertig

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Integrated immunological analysis of a successful conversion of locally advanced hepatocellular carcinoma to resectability with neoadjuvant therapy by Ihab Kamel, Elizabeth Jaffee, Qingfeng Zhu, Robert Anders, Won Jin Ho, Mark Yarchoan, Matthew Weiss, Elana J Fertig, Gaurav Sharma, Aleksandra Popovic, Jennifer Durham, Genevieve Stein-O'Brien, Guanglan Mo

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Entinostat in combination with nivolumab in metastatic pancreatic ductal adenocarcinoma: a phase 2 clinical trial by Marina Baretti, Ludmila Danilova, Jennifer N. Durham, Courtney B. Betts, Leslie Cope, Dimitrios N. Sidiropoulos, Joseph A. Tandurella, Soren Charmsaz, Nicole Gross, Alexei Hernandez, Won Jin Ho, Chris Thoburn, Rosalind Walker, James Leatherman, Sarah Mitchell, Brian Christmas, Ali Saeed, Daria A. Gaykalova, Srinivasan Yegnasubramanian, Elana J. Fertig, Lisa M. Coussens, Mark Yarchoan, Elizabeth Jaffee, Nilofer S. Azad

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Ten challenges and opportunities in computational immuno-oncology by Hong Zhang, Riyue Bao, Song Liu, Mark Long, Sacha Gnjatic, Yi Xing, Elana J Fertig, Alan Hutson, Martin Morgan, Eytan Ruppin, Anant Madabhushi, Natalie Vokes, Daoud Meerzaman, Edgar Gonzalez-Kozlova, Vanessa D Jonsson, Eliezer M Van Allen, Spencer R Rosario, Jennifer Altreuter, Himangi Marathe, Jill S Barnholtz-Sloan, Lyndsay Harris, Qingrong Chen, James Dignam, Andrew J Gentles, Erika Kim, David Van Valen

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CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial by Janelle M. Montagne, Jacob T. Mitchell, Joseph A. Tandurella, Eric S. Christenson, Ludmila V. Danilova, Atul Deshpande, Melanie Loth, Dimitrios N. Sidiropoulos, Emily Davis-Marcisak, Daniel R. Bergman, Qingfeng Zhu, Hao Wang, Luciane T. Kagohara, Logan L. Engle, Benjamin F. Green, Alexander V. Favorov, Won Jin Ho, Su Jin Lim, Rui Zhang, Pan Li, Jessica Gai, Guanglan Mo, Sarah Mitchell, Rulin Wang, Ajay Vaghasia, Wenpin Hou, Yao Xu, Jacquelyn W. Zimmerman, Jennifer H. Elisseeff, Srinivasan Yegnasubramanian, Robert A. Anders, Elizabeth M. Jaffee, Lei Zheng, Elana J. Fertig

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