Status of HIV vaccine development: progress and promise by Barton F. Haynes, Kevin O. Saunders, Beatrice H. Hahn, Kevin Wiehe, Lindsey R. Baden, George M. Shaw

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Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys. by So-Yon Lim, Tiffany Chan, Rebecca S Gelman, James B Whitney, Kara L O'Brien, Dan H Barouch, David B Goldstein, Barton F Haynes, Norman L Letvin

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HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC. by Natasha Wood, Tanmoy Bhattacharya, Brandon F Keele, Elena Giorgi, Michael Liu, Brian Gaschen, Marcus Daniels, Guido Ferrari, Barton F Haynes, Andrew McMichael, George M Shaw, Beatrice H Hahn, Bette Korber, Cathal Seoighe

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Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection. by Holger B Kramer, Kerry J Lavender, Li Qin, Andrea R Stacey, Michael K P Liu, Katalin di Gleria, Alison Simmons, Nancy Gasper-Smith, Barton F Haynes, Andrew J McMichael, Persephone Borrow, Benedikt M Kessler

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Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans. by Nelson R Wu, Nathan I Nicely, Esther M Lee, Rachel K Reed, Brian E Watts, Fangping Cai, William E Walkowicz, Baptiste Aussedat, Julia A Jones, Amanda Eaton, Ashley M Trama, S Munir Alam, David C Montefiori, Barton F Haynes, Kevin O Saunders

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A Pentavalent HIV-1 Subtype C Vaccine Containing Computationally Selected gp120 Strains Improves the Breadth of V1V2 Region Responses by Xiaoying Shen, Bette Korber, Rachel L. Spreng, Sheetal S. Sawant, Allan deCamp, Arthur S. McMillan, Ryan Mathura, Susan Zolla-Pazner, Abraham Pinter, Robert Parks, Cindy Bowman, Laura Sutherland, Richard Scearce, Nicole L. Yates, David C. Montefiori, Barton F. Haynes, Georgia D. Tomaras

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Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses. by Matthew Zirui Tay, Pinghuang Liu, LaTonya D Williams, Michael D McRaven, Sheetal Sawant, Thaddeus C Gurley, Thomas T Xu, S Moses Dennison, Hua-Xin Liao, Agnès-Laurence Chenine, S Munir Alam, M Anthony Moody, Thomas J Hope, Barton F Haynes, Georgia D Tomaras

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Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8. by Cinque Soto, Gilad Ofek, M Gordon Joyce, Baoshan Zhang, Krisha McKee, Nancy S Longo, Yongping Yang, Jinghe Huang, Robert Parks, Joshua Eudailey, Krissey E Lloyd, S Munir Alam, Barton F Haynes, NISC Comparative Sequencing Program, James C Mullikin, Mark Connors, John R Mascola, Lawrence Shapiro, Peter D Kwong

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Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. by Will Fischer, Vitaly V Ganusov, Elena E Giorgi, Peter T Hraber, Brandon F Keele, Thomas Leitner, Cliff S Han, Cheryl D Gleasner, Lance Green, Chien-Chi Lo, Ambarish Nag, Timothy C Wallstrom, Shuyi Wang, Andrew J McMichael, Barton F Haynes, Beatrice H Hahn, Alan S Perelson, Persephone Borrow, George M Shaw, Tanmoy Bhattacharya, Bette T Korber

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Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection. by Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K P Liu, Emma L Turnbull, Jesus F Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D Tomaras, Barton F Haynes, Clive M Gray, Persephone Borrow, Mario Roederer, Andrew J McMichael, Kent J Weinhold

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Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. by Fangping Cai, Wei-Hung Chen, Weimin Wu, Julia A Jones, Misook Choe, Neelakshi Gohain, Xiaoying Shen, Celia LaBranche, Amanda Eaton, Laura Sutherland, Esther M Lee, Giovanna E Hernandez, Nelson R Wu, Richard Scearce, Michael S Seaman, M Anthony Moody, Sampa Santra, Kevin Wiehe, Georgia D Tomaras, Kshitij Wagh, Bette Korber, Mattia Bonsignori, David C Montefiori, Barton F Haynes, Natalia de Val, M Gordon Joyce, Kevin O Saunders

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Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting. by Nicole A Doria-Rose, Han R Altae-Tran, Ryan S Roark, Stephen D Schmidt, Matthew S Sutton, Mark K Louder, Gwo-Yu Chuang, Robert T Bailer, Valerie Cortez, Rui Kong, Krisha McKee, Sijy O'Dell, Felicia Wang, Salim S Abdool Karim, James M Binley, Mark Connors, Barton F Haynes, Malcolm A Martin, David C Montefiori, Lynn Morris, Julie Overbaugh, Peter D Kwong, John R Mascola, Ivelin S Georgiev

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Copy number variation of KIR genes influences HIV-1 control. by Kimberly Pelak, Anna C Need, Jacques Fellay, Kevin V Shianna, Sheng Feng, Thomas J Urban, Dongliang Ge, Andrea De Luca, Javier Martinez-Picado, Steven M Wolinsky, Jeremy J Martinson, Beth D Jamieson, Jay H Bream, Maureen P Martin, Persephone Borrow, Norman L Letvin, Andrew J McMichael, Barton F Haynes, Amalio Telenti, Mary Carrington, David B Goldstein, Galit Alter, NIAID Center for HIV/AIDS Vaccine Immunology

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Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge by Dieter Mielke, Marina Tuyishime, Natasha S. Kelkar, Yunfei Wang, Robert Parks, Sampa Santra, Wes Rountree, LaTonya D. Williams, Tiffany Peters, Nathan Eisel, Sheetal Sawant, Lu Zhang, Derrick Goodman, Shalini Jha, Adam Zalaquett, Pratamesh Ramasubramanian, Sherry Stanfield-Oakley, Gary Matyas, Zoltan Beck, Mangala Rao, Julie Ake, Thomas N. Denny, David C. Montefiori, Margaret E. Ackerman, Lawrence Corey, Georgia D. Tomaras, Bette T. Korber, Barton F. Haynes, Xiaoying Shen, Guido Ferrari

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Improving Mycobacterium bovis bacillus Calmette-Guèrin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. by Manjunatha M Venkataswamy, Tony W Ng, Shalu S Kharkwal, Leandro J Carreño, Alison J Johnson, Shajo Kunnath-Velayudhan, Zheng Liu, Robert Bittman, Peter J Jervis, Liam R Cox, Gurdyal S Besra, Xiangshu Wen, Weiming Yuan, Moriya Tsuji, Xiangming Li, David D Ho, John Chan, Sunhee Lee, Richard Frothingham, Barton F Haynes, Michael W Panas, Geoffrey O Gillard, Jaimie D Sixsmith, Birgit Korioth-Schmitz, Joern E Schmitz, Michelle H Larsen, William R Jacobs, Steven A Porcelli

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Common genetic variation and the control of HIV-1 in humans. by Jacques Fellay, Dongliang Ge, Kevin V Shianna, Sara Colombo, Bruno Ledergerber, Elizabeth T Cirulli, Thomas J Urban, Kunlin Zhang, Curtis E Gumbs, Jason P Smith, Antonella Castagna, Alessandro Cozzi-Lepri, Andrea De Luca, Philippa Easterbrook, Huldrych F Günthard, Simon Mallal, Cristina Mussini, Judith Dalmau, Javier Martinez-Picado, José M Miro, Niels Obel, Steven M Wolinsky, Jeremy J Martinson, Roger Detels, Joseph B Margolick, Lisa P Jacobson, Patrick Descombes, Stylianos E Antonarakis, Jacques S Beckmann, Stephen J O'Brien, Norman L Letvin, Andrew J McMichael, Barton F Haynes, Mary Carrington, Sheng Feng, Amalio Telenti, David B Goldstein, NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI)

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