Proximity interactome of alphavirus replicase component nsP3 includes proviral host factors eIF4G and AHNAK. by Aditya Thiruvaiyaru, Sari Mattila, Mohammadreza Sadeghi, Krystyna Naumenko, Andres Merits, Markku Varjosalo, Tero Ahola

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Dengue Virus Inhibitors as Potential Broad-Spectrum Flavivirus Inhibitors by Larisa Ivanova, Krystyna Naumenko, Margus Varjak, Sandra Koit, Yehudit Morozovsky, Andres Merits, Mati Karelson, Eva Zusinaite

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Attenuated Getah virus confers protection against multiple arthritogenic alphaviruses. by Zhiwen Jiang, Andres Merits, Ying Qin, Gang Xing, Letian Zhang, Jie Chen, Ningning Wang, Margus Varjak, Xiaofeng Zhai, Dongyan Li, Wanjie Song, Shuo Su

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Wolbachia Blocks Viral Genome Replication Early in Infection without a Transcriptional Response by the Endosymbiont or Host Small RNA Pathways. by Stephanie M Rainey, Julien Martinez, Melanie McFarlane, Punita Juneja, Peter Sarkies, Aleksei Lulla, Esther Schnettler, Margus Varjak, Andres Merits, Eric A Miska, Francis M Jiggins, Alain Kohl

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Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication. by Melanie McFarlane, Camilo Arias-Goeta, Estelle Martin, Zoe O'Hara, Aleksei Lulla, Laurence Mousson, Stephanie M Rainey, Suzana Misbah, Esther Schnettler, Claire L Donald, Andres Merits, Alain Kohl, Anna-Bella Failloux

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Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine. by Peiqi Yin, Elizabeth B Sobolik, Nicholas A May, Sainan Wang, Atef Fayed, Dariia Vyshenska, Adam M Drobish, M Guston Parks, Laura Sandra Lello, Andres Merits, Thomas E Morrison, Alexander L Greninger, Margaret Kielian

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Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus. by Julio Rodriguez-Andres, Seema Rani, Margus Varjak, Margo E Chase-Topping, Markus H Beck, Mhairi C Ferguson, Esther Schnettler, Rennos Fragkoudis, Gerald Barry, Andres Merits, John K Fazakerley, Michael R Strand, Alain Kohl

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Chlorinated biscoumarins inhibit chikungunya virus replication in cell-based and animal models by Chidinma Nelson Orji, Naphat Loeanurit, Van-Can Pham, Thi-Hong-Truc Phan, Kowit Hengphasatporn, Yasuteru Shigeta, Altri Diana Putri, Laura Sandra Lello, Andres Merits, Noppadol Wacharachaisurapol, Wanna Eiamart, Supeecha Wittayalertpanya, Tanatorn Khotavivattana, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn

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Mutating chikungunya virus non‐structural protein produces potent live‐attenuated vaccine candidate by Yi‐Hao Chan, Teck‐Hui Teo, Age Utt, Jeslin JL Tan, Siti Naqiah Amrun, Farhana Abu Bakar, Wearn‐Xin Yee, Etienne Becht, Cheryl Yi‐Pin Lee, Bernett Lee, Ravisankar Rajarethinam, Evan Newell, Andres Merits, Guillaume Carissimo, Fok‐Moon Lum, Lisa FP Ng

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Kaurenoic acid is a potent inhibitor of SARS-CoV-2 RNA synthesis, virion assembly, and release in vitro by Igor Andrade Santos, Igor Andrade Santos, Victoria Riquena Grosche, Victoria Riquena Grosche, Victoria Riquena Grosche, Natasha Marques Cassani, Natasha Marques Cassani, Rodrigo Cássio Sola Veneziani, Gustavo Lima Ribeiro, Jairo Kenupp Bastos, Nilson Nicolau-Junior, Andres Merits, Carlos Henrique Gomes Martins, Mark Harris, Ana Carolina Gomes Jardim, Ana Carolina Gomes Jardim

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Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus‐specific neutralizing antibody response by Zhisheng Her, Terk‐Shin Teng, Jeslin JL Tan, Teck‐Hui Teo, Yiu‐Wing Kam, Fok‐Moon Lum, Wendy WL Lee, Christelle Gabriel, Rossella Melchiotti, Anand K Andiappan, Valeria Lulla, Aleksei Lulla, Mar K Win, Angela Chow, Subhra K Biswas, Yee‐Sin Leo, Marc Lecuit, Andres Merits, Laurent Rénia, Lisa FP Ng

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In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2. by Agnieszka M Szemiel, Andres Merits, Richard J Orton, Oscar A MacLean, Rute Maria Pinto, Arthur Wickenhagen, Gauthier Lieber, Matthew L Turnbull, Sainan Wang, Wilhelm Furnon, Nicolas M Suarez, Daniel Mair, Ana da Silva Filipe, Brian J Willett, Sam J Wilson, Arvind H Patel, Emma C Thomson, Massimo Palmarini, Alain Kohl, Meredith E Stewart

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A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. by Suzannah J Rihn, Andres Merits, Siddharth Bakshi, Matthew L Turnbull, Arthur Wickenhagen, Akira J T Alexander, Carla Baillie, Benjamin Brennan, Fiona Brown, Kirstyn Brunker, Steven R Bryden, Kerry A Burness, Stephen Carmichael, Sarah J Cole, Vanessa M Cowton, Paul Davies, Chris Davis, Giuditta De Lorenzo, Claire L Donald, Mark Dorward, James I Dunlop, Matthew Elliott, Mazigh Fares, Ana da Silva Filipe, Joseph R Freitas, Wilhelm Furnon, Rommel J Gestuveo, Anna Geyer, Daniel Giesel, Daniel M Goldfarb, Nicola Goodman, Rory Gunson, C James Hastie, Vanessa Herder, Joseph Hughes, Clare Johnson, Natasha Johnson, Alain Kohl, Karen Kerr, Hannah Leech, Laura Sandra Lello, Kathy Li, Gauthier Lieber, Xiang Liu, Rajendra Lingala, Colin Loney, Daniel Mair, Marion J McElwee, Steven McFarlane, Jenna Nichols, Kyriaki Nomikou, Anne Orr, Richard J Orton, Massimo Palmarini, Yasmin A Parr, Rute Maria Pinto, Samantha Raggett, Elaine Reid, David L Robertson, Jamie Royle, Natalia Cameron-Ruiz, James G Shepherd, Katherine Smollett, Douglas G Stewart, Meredith Stewart, Elena Sugrue, Agnieszka M Szemiel, Aislynn Taggart, Emma C Thomson, Lily Tong, Leah S Torrie, Rachel Toth, Margus Varjak, Sainan Wang, Stuart G Wilkinson, Paul G Wyatt, Eva Zusinaite, Dario R Alessi, Arvind H Patel, Ali Zaid, Sam J Wilson, Suresh Mahalingam

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