Polycomb targets seek closest neighbours. by Mita Chotalia, Ana Pombo

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Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. by Miguel R Branco, Ana Pombo

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Editorial: Sea cucumbers: the sustainability of emergent and historical resources by Pedro M. Félix, Ana Pombo, Arnold Rakaj, Christopher M. Pearce

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How increasing temperature affects the innate immune system of sea urchin Paracentrotus lividus (Lamarck, 1816) reared in a RAS system by Ana Filipa Rodrigues, Sílvia Lourenço, Ana S. Gomes, Carolina F. Tchobanov, Ana Pombo, Teresa Baptista

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Poised transcription factories prime silent uPA gene prior to activation. by Carmelo Ferrai, Sheila Q Xie, Paolo Luraghi, Davide Munari, Francisco Ramirez, Miguel R Branco, Ana Pombo, Massimo P Crippa

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Transcription and chromatin organization of a housekeeping gene cluster containing an integrated beta-globin locus control region. by Daan Noordermeer, Miguel R Branco, Erik Splinter, Petra Klous, Wilfred van Ijcken, Sigrid Swagemakers, Manousos Koutsourakis, Peter van der Spek, Ana Pombo, Wouter de Laat

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RNA polymerase II primes Polycomb‐repressed developmental genes throughout terminal neuronal differentiation by Carmelo Ferrai, Elena Torlai Triglia, Jessica R Risner‐Janiczek, Tiago Rito, Owen JL Rackham, Inês de Santiago, Alexander Kukalev, Mario Nicodemi, Altuna Akalin, Meng Li, Mark A Ungless, Ana Pombo

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Extensive folding variability between homologous chromosomes in mammalian cells by Ibai Irastorza-Azcarate, Alexander Kukalev, Rieke Kempfer, Christoph J Thieme, Guido Mastrobuoni, Julia Markowski, Gesa Loof, Thomas M Sparks, Emily Brookes, Kedar Nath Natarajan, Stephan Sauer, Amanda G Fisher, Mario Nicodemi, Bing Ren, Roland F Schwarz, Stefan Kempa, Ana Pombo

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Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation by James Fraser, Carmelo Ferrai, Andrea M Chiariello, Markus Schueler, Tiago Rito, Giovanni Laudanno, Mariano Barbieri, Benjamin L Moore, Dorothee CA Kraemer, Stuart Aitken, Sheila Q Xie, Kelly J Morris, Masayoshi Itoh, Hideya Kawaji, Ines Jaeger, Yoshihide Hayashizaki, Piero Carninci, Alistair RR Forrest, The FANTOM Consortium, Colin A Semple, Josée Dostie, Ana Pombo, Mario Nicodemi

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