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21661
Clinical characteristics and risk factors of bacillary layer detachment in central serous chorioretinopathy: a comparative multicenter study
Published 2024-12-01“…Inclusion criteria included a CSC diagnosis with RPE leakage, BALAD confirmed by three authors, age over 18, and a detailed medical history from the 30 days before symptom onset. The study assessed visual acuity, choroidal thickness, psychiatric disorders, corticosteroid use, prior CSC treatments, and hyperreflective material on OCT. …”
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21662
Comparative Efficacy of Bone Graft Materials in Transforaminal Lumbar Interbody Fusion: A Systematic Review and Meta-Analysis
Published 2025-07-01“…Aim This study aims to compare the efficacy and safety of different bone graft materials used in TLIF surgeries by analyzing fusion rates, clinical outcomes, and complication rates across various studies. Methods A systematic search was conducted on PubMed and Google Scholar for studies related to TLIF and bone graft materials up to December 2023. …”
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21663
Association between out-of-pocket expenditure and health-related quality of life among patients receiving cancer treatment: a cross-sectional study from Nepal
Published 2025-07-01“…We used the European Quality of Life 5 dimensions (EQ-5D-5L) and the European Quality of Life Visual Analogue Scale (EQ-VAS) to obtain their HRQoL. …”
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21664
Effects of exercise and exercise timing on energy intake and appetite control in Danish individuals with overweight or obesity with and without type 2 diabetes: a protocol for a ra...
Published 2025-02-01“…Introduction The aim of this study is to investigate the effects of acute exercise on appetite control and whether this differs between morning and late afternoon in individuals with overweight/obesity with or without type 2 diabetes (T2D).Methods and analysis The hedonic and homeostatic appetite control in obesity and type 2 diabetes in the context of meal and exercise timing (TIMEX) study is a randomised, controlled, cross-over trial. …”
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21665
Efficiency and safety of leflunomide in rheumatoid arthritis: Results of a Russian observational multicenter of trial
Published 2015-06-01“…In 2011, the Russian Federation registered and since it has been successfully using leflunomide**.Objective: to evaluate the efficacy and tolerability of leflunomide** used to treat RA in routine clinical practice.Subjects and methods.The investigation enrolled patients with varying duration of RA that met the 1987 classification criteria. …”
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21666
Dynamical network-based evaluation for neuromuscular dysfunction in stroke-induced hemiplegia during standing
Published 2024-10-01“…This study aimed to investigate the hemiplegia-linked neuromuscular dysfunction during standing from the perspective of multi-muscle dynamical coordination by utilizing a novel network approach – weighted recurrence network (WRN). Methods Ten male hemiplegic patients with first-ever stroke and 10 age-matched healthy male adults were instructed to stand on a platform quietly for 30 s with eyes opened and eyes closed, respectively. …”
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21667
Effect of holistic nursing interventions for patients undergoing Laser-assisted tympanostomy under otoendoscopy for secretory otitis media (分泌性中耳炎耳内镜下鼓膜激光打孔治疗中整体护理干预的应用效果)...
Published 2021-03-01“…Objective To investigate the effect of holistic nursing intervention for patients undergoing Laser-assisted tympanostomy under otoendoscopy for secretory otitis media. Methods Totally 126 (155 ears) patients with secretory otitis media were randomly divided into the observation group and the control group, with 63 cases in each group. …”
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21668
Path model explaining the association between fear of falling and health-related quality of life in (pre-)frail older adults
Published 2025-02-01“…Unlike previous studies that examined only few mediating variables, this study aimed to develop a more comprehensive path model explaining the association between FoF and HrQoL. Methods A theoretical path model was developed based on existing evidence and expert feedback and fitted to cross-sectional baseline data on 385 community-dwelling (pre-)frail older adults from the PromeTheus randomized controlled trial using robust weighted least squares estimation. …”
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21669
Percutaneous unilateral biportal endoscopic discectomy for symptomatic lumbar disc herniation in geriatric patients
Published 2025-01-01“…PurposeThe purpose of this study is to investigate the surgical efficacy and safety of percutaneous unilateral biportal endoscopic discectomy (UBED) for symptomatic lumbar disc herniation (LDH) in geriatric patients.MethodsSeventy-two geriatric patients, aged 65–86 years (mean age: 73.2 years), with single or two-level LDH who underwent UBED from January 2020 to September 2022 were retrospectively analyzed. …”
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21670
Thioredoxin-interacting protein (TXNIP) inhibition promotes retinal ganglion cell survival and facilitates M1-like microglial transformation via the PI3K/Akt pathway in glaucoma
Published 2024-12-01“…In addition, we found that ablation of TXNIP promoted retinal ganglion cells (RGCs) survival and alleviated visual function impairment in experimental glaucoma. …”
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21671
AI-Based Noise-Reduction Filter for Whole-Body Planar Bone Scintigraphy Reliably Improves Low-Count Images
Published 2024-11-01“…<b>Results</b>: Based on visual assessment, observers agreed that image contrast and quality were better in the BS-AI-filtered images, increasing their diagnostic confidence. …”
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21672
A Closer Look at Periocular Necrotizing Fasciitis: A Systematic Review of Literature
Published 2025-05-01“…To address this critical issue, we conducted the largest and most comprehensive systematic review to date, providing valuable insights into the diagnosis and treatment of PNF to improve clinical practice and patient prognosis. <b>Methods</b>: A search on Pubmed, Scopus, Embase, and WOS from January 2013 to August 2024 was performed. …”
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21673
Multidisciplinary, Clinical Assessment of Accelerated Deep-Learning MRI Protocols at 1.5 T and 3 T After Intracranial Tumor Surgery and Their Influence on Residual Tumor Perception
Published 2025-08-01“…The image quality metrics NQM, SNR, and PSNR showed better results for DLR. Visual assessment of residual tumor was similar at 3 T but differed at 1.5 T, with more residual tumor detected with DLR, especially by the neurosurgeon (<i>n</i> = 4). …”
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21674
Computational analysis of reproducibility and image quality of 2011 and 2017 models of Heidelberg Spectralis SD-OCT machines
Published 2025-04-01“…Subjects and participants: Fourteen healthy individuals (28 eyes, age range: 22-54 years) underwent TRT measurements using both Old and New OCT models, with each eye receiving three consecutive scans per visit. Methods and testing: TRT measurements were performed using the Posterior Pole Algorithm (PPA) and Early Treatment Diabetic Retinopathy Study (ETDRS) grid protocols. …”
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21675
Comprehensive coronary CT angiography in people living with HIV: a systematic review and meta-analysis
Published 2025-02-01“…Publication bias was assessed by visual inspection of funnel plots and formal testing by Egger’s and Begg’s tests. …”
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21676
Development and validation of a clinical-friendly model for predicting 180-day mortality in the older with community-acquired pneumonia
Published 2025-04-01“…We aimed to develop and validate a pneumonia scoring system to predict 180-day mortality, and compare its performance with the commonly used CURB-65 score. Methods The prospective cohort study enrolled patients aged 65 years and older with CAP from 10 medical centers in China between April 2021 and December 2023. …”
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21677
Standardization of Beef, Pork, Chicken, and Soy Protein Extracts for Patch Testing and Their Accuracy in Diagnosing Adverse Food Reactions in Dogs with Chronic Pruritus
Published 2025-04-01“…They underwent an elimination diet (ED) and were evaluated using the pruritus visual analog scale (pVAS) and lesion scores (CADESI-4) before and after the ED (days 0 and 45). …”
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21678
Clinical effect analysis of unilateral percutaneous vertebral cement distribution in the repair of osteoporotic thoracolumbar vertebral compression fractures
Published 2025-03-01“…Objective This study aimed to investigate the impact of cement distribution on the efficacy of vertebral compression fracture repair to provide effective preventive and therapeutic measures, prevent postoperative vertebral re-fracture, and improve surgical outcomes. Methods A total of 170 patients who underwent unilateral percutaneous vertebroplasty at our hospital from January 2020 to December 2022 were selected. …”
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21679
Association between ABCB1 Gene Polymorphisms and Labor Analgesia in Primiparas
Published 2024-09-01“…Visual analog scale (VAS) scores were recorded at 0, 1, and 2 h, respectively, after epidural analgesia. …”
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21680
Associations between serum lipid profiles and the incidence of chronic obstructive pulmonary disease in the UK Biobank
Published 2025-08-01“…Abstract Objective To investigate the relationship between serum lipid levels and the risk of Chronic obstructive pulmonary disease (COPD) in the UK Biobank. Methods We performed this prospective study in 381,938 adults without COPD from UK Biobank. …”
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