Chronic Isolated Fracture of the Metatarsal Head in Lesser Toes Treated with Open Reduction and Internal Fixation by Wenjing Li MD, Ying Li MD

“…This study aims to report the clinical and imaging characteristics, as well as treatment results, of these fractures. Methods: A retrospective consecutive case-series study was performed on 5 patients with symptomatic chronic isolated shear fracture of a metatarsal head in the lesser toes from January 2018 to April 2021. …”
Get full text

Impact of Sagittal Spinal Balance on Functional Recovery After PLIF of L5‐S1 Isthmic Spondylolisthesis With Lumbar Spinal Stenosis by Jiaheng Lv, Quan Zhou, Wei He, Tianci Fang, Yujie Shen, Yulin Chen, Hao Liu, Huilin Yang, Yifei Zheng, Tao Liu

“…This study analyzes the influence of residual sagittal imbalanceon health‐related quality of life (HRQOL) after PLIF for L5‐S1 IS with LSS, aiming to optimize surgical correction and prognostic accuracy. Methods This study analyzed 103 consecutive patients with L5‐S1 IS and LSS undergoing PLIF from 2020 to 2022, followed at 3 days, 3 months, and ≥ 1 year postoperatively, using SPSS 26.0 for statistical analysis. …”
Get full text

Human congenital cataract mutation in MYH9 alters F-actin organization and cell functions by Hao Yuan, Zhen-Yu Wang, Jia-Rui Yang, Chen Huang, Liang Zhu, Xue-Min Li

Get full text

Evaluation of a Novel eHealth Tool for Pulmonary Rehabilitation in People With Chronic Obstructive Pulmonary Disease: Randomized Controlled Pilot and Feasibility Trial by Åsa Karlsson, Pernilla Sönnerfors, Sara Lundell, Annika Toots, Karin Wadell

“…Moreover, this study aims to evaluate clinical outcome measures to prepare for a future larger trial. MethodsA multicenter, parallel-group randomized controlled pilot and feasibility trial was conducted in 6 primary health care centers. …”
Get full text

Association between clinical and MRI‐detected imaging findings for people with midfoot pain, a cross‐sectional study by Jill Halstead, Carmen Martín‐Hervás, Elizabeth M. A. Hensor, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, John B. Arnold, Jennifer Jones, Anthony C. Redmond

“…Foot pain and disability were recorded using visual analog scales (VAS) and the Modified‐Manchester Foot Pain Disability Index (MMFPDI). …”
Get full text

Building evidences in Public Health Emergency Preparedness (“BePHEP” Project)—a systematic review by Michelangelo Mercogliano, Gloria Spatari, Chiara Noviello, Francesca Di Serafino, Maria Elisabetta Mormile, Giuseppa Granvillano, Annalisa Iagnemma, Riccardo Mimmo, Irene Schenone, Eleonora Raso, Andrea Sanna, Enrica Frasson, Veronica Gallinoro, Marcello Di Pumpo, Duha Shellah, Caterina Rizzo, Nunzio Zotti

“…Nigeria experienced a rise in measles cases during armed conflicts despite vaccination efforts, while visual communication strategies improved SARS-CoV-2 vaccination rates. …”
Get full text

Single-cell analysis reveals the loss of FABP4-positive proliferating valvular endothelial cells relates to functional mitral regurgitation by Xiaohu Wang, Mengxia Fu, Weiteng Wang, Songren Shu, Ningning Zhang, Ruojin Zhao, Xiao Chen, Xiumeng Hua, Xin Wang, Wei Feng, Xianqiang Wang, Jiangping Song

“…Key findings from the scRNA-seq analysis were validated using pathological staining to visualize key markers in the mitral valve leaflets. …”
Get full text

Clinical efficacy of Ni-Ti memory alloy four-corner arthrodesis concentrator in the treatment of scaphoid nonunion advanced collapse: a follow-up of over 10 years by Baochuang Qi, Minzheng Guo, Chen Meng, Teng Wang, Chuan Li, Yongqing Xu

“… Purpose: Exploring the therapeutic effects of Ni-Ti shape memory alloy four-corner arthrodesis concentrator (NT-FCAC) in treating scaphoid nonunion advanced collapse (SNAC) and providing a decade-long follow-up report. Materials and methods: Twenty-six patients with SNAC underwent scaphoidectomy, along with four-corner arthrodesis fusion involving the capitate, lunate, triquetrum, and hamate, using NT-MFCAC. …”
Get full text

Comparative study of chitosan-based liquid dressing and recombinant human epidermal growth factor on acute limb skin wound healing: A randomized controlled trial by Dunyong Tan, Jiawei Guo, Xiaoqiang Chen, Jianquan Liu, Siyao Yang, Daping Wang, Wencui Li

“…However, its efficacy and safety are yet to be sufficiently verified in patients. Methods: This randomized controlled trial enrolled 40 patients suffering from acute skin wounds in the limbs from 12/2022 to 12/2023. …”
Get full text

Natural orifice transluminal endoscopic surgery in urology: The Chinese experience by Xiaofeng Zou, Guoxi Zhang, Tianpeng Xie, Yuanhu Yuan, Rihai Xiao, Gengqing Wu, Xiaoning Wang, Hui Xu, Folin Liu, Yuting Wu, Yunfeng Liao, Quanliang Liu, Yinghao Sun, Bo Yang, Linhui Wang, Chuanliang Xu, Xiaofeng Gao

“…Objective: To describe the Chinese experience of natural orifice transluminal endoscopic surgery (NOTES) in urology. Methods: From December 2008 to May 2017, 35 animal experiments and 305 clinical surgeries of NOTES or natural orifices specimen extractions (NOSE) were performed in China. …”
Get full text

Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes by Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

“…Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps, has been associated with unfavorable 90‐day functional outcomes despite successful reperfusion. …”
Get full text

Impacts of Traditional Warm-Up and Post-Activation Potentiation on Muscle Endurance During the Back Squat: Response of Blood Lactate, Perceived Effort, and Time Under Tension by Taianda M. Amorim, Alexandre V. Gurgel, Viviane Faleiro, Thiago T. Guimarães, Estêvão R. Monteiro, Felipe G. Teixeira, Bruno Jotta, Tiago C. Figueiredo, Raquel C. Castiglione, Silvio R. Marques-Neto

“…This randomized crossover study compared the acute effects of traditional and PAP-based warm-ups on local muscular endurance (LME) during free weight back squats in resistance-trained men. Methods: Twelve trained males (age: 41.3 ± 5.7 years; one repetition maximum squat: 129.3 ± 14.3 kg) completed three randomized squat sessions: mobility with LME (M + LME), traditional warm-up with LME (T + LME), and PAP with LME (PAP + LME). …”
Get full text

Transcutaneous electrical nerve stimulation as an adjuvant treatment for thoracolumbar acute hyperesthesia in chondrodystrophic dogs: a prospective blinded controlled clinical stud... by Débora Gouveia, Débora Gouveia, Débora Gouveia, Ana Cardoso, Ana Cardoso, Carla Carvalho, Marina Moisés, André Coelho, André Coelho, André Coelho, Maria Manuel Balça, Maria Manuel Balça, Maria Manuel Balça, Rui Alvites, Rui Alvites, Rui Alvites, Rui Alvites, Ana Colette Maurício, Ana Colette Maurício, Ana Colette Maurício, António Ferreira, António Ferreira, Ângela Martins, Ângela Martins, Ângela Martins

“…This study aimed to evaluate the efficacy of TENS as an adjunctive treatment for thoracolumbar paraspinal hyperesthesia in dogs.MethodsThis prospective, blinded, controlled cohort study was conducted in a clinical setting. …”
Get full text

Effect of Traditional Chinese Formula Dingkun Pill on Primary Dysmenorrhea: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial by Xuesong Ding, Shiyang Zhu, Yan Deng, Xiao Ma, Jingwen Gan, Yanfang Wang, Aijun Sun

“…Therefore, this trial aimed to assess the efficacy and safety of DKP in patients with PD. Methods: Our study was a multicenter, prospective, randomized, double-blind, placebo-controlled study. …”
Get full text

Sub‐Acromioclavicular Decompression Increases the Risk of Postoperative Shoulder Stiffness after Arthroscopic Rotator Cuff Repair by Cheng Li, Zhiling Wang, Maslah Idiris Ali, Yi Long, Ymuhanmode Alike, Min Zhou, Dedong Cui, Zhenze Zheng, Ke Meng, Jingyi Hou, Rui Yang

“…This study is aim to evaluate the impact of additional sub‐acromioclavicular (SAC) decompression during arthroscopic rotator cuff repair on the postoperative shoulder stiffness (POSS) in patients. Methods This retrospective study examined digital data from patients with full‐thickness rotator cuff tears who underwent arthroscopic rotator cuff repair at a local institution. …”
Get full text

The Potential Benefits of a Novel Food Supplement Based on Cannabis Sativa, Boswellia, and Fish Oil for Pain and Inflammation in Physical Activity: Unraveling the Role of Orexin-A... by Antonietta Messina, Antonietta Monda, Valentina Vassallo, Girolamo Di Maio, Rita Polito, Marco La Marra, Salvatore Allocca, Maria Casillo, Fiorenzo Moscatelli, Cristina Scavone, Francesco Taturi, Vincenzo Monda, Giovanni Messina, Chiara Schiraldi, Marcellino Monda

“…Pain was assessed using the Visual Analog Scale (VAS). Metabolic parameters, inflammatory cytokines (IL-6, IL-8, TNF-α, IFN-γ, and IL-10), and serum orexin-A levels were measured before and after the intervention. …”
Get full text

Gadoxetic acid-enhanced MRI for identifying cholangiocyte phenotype hepatocellular carcinoma by interpretable machine learning: individual application of SHAP by Wei Liu, Zhiping Cai, Yifan Chen, Xingqun Guan, Jieying Feng, Haixiong Chen, Baoliang Guo, Fusheng OuYang, Chun Luo, Rong Zhang, Xinjie Chen, Xiaohong Li, Cuiru Zhou, Shaomin Yang, Ziwei Liu, Qiugen Hu

“…This study aims to develop and validate an optimal machine learning model to predict cholangiocyte phenotype HCC based on T1 mapping gadoxetic acid-enhanced MRI and to implement individual applications via the Shapley Additive explanation (SHAP). Methods We included 180 patients with histologically confirmed HCC from two institutions. …”
Get full text

Post-exertional malaise in Long COVID: subjective reporting versus objective assessment by Barbara Stussman, Nathan Camarillo, Gayle McCrossin, Marybeth Stockman, Gina Norato, C. Stephenie Vetter, Alenka Ferrufino, Ashade Adedamola, Nicholas Grayson, Avindra Nath, Leighton Chan, Brian Walitt, Lisa M. K. Chin

“…EC also performed a standardized exercise test (cardiopulmonary exercise test, CPET), and the PEM response to CPET was assessed using visual analog scales and qualitative interviews (QIs) administered serially over 72 h. …”
Get full text

Impact of postoperative depression and immune-inflammatory biomarkers on the prognosis of patients with esophageal cancer receiving minimally invasive esophagectomy: a retrospectiv... by Pei-xin Tan, Lin-xin Wu, Shuang Ma, Shi-jing Wei, Tai-hang Wang, Bing-chen Wang, Bing-bing Fu, Jia-shuo Yang, Qing Zhao, Qing Zhao, Li Sun, Yi Liu, Tao Yan

“…This study aimed to investigate the interrelationship between depression and prognosis in patients with EC, with a focus on immune-inflammatory biomarkers.MethodsThis single-center retrospective trial was conducted at the National Cancer Center/Cancer Hospital of the Chinese Academy of Medical Sciences. …”
Get full text

EFFICIENCY OF DYNAMIC ELECTRONEUROSTIMULATION IN KNEE OSTEOARTHRITIS: RESULTS OF A MULTICENTER RANDOMIZED STUDY by O. M. Lesnyak, E. Yu. Kadochnikova, L. I. Alekseeva, I. G. Dydykina, O. B. Ershova, E. M. Zaitseva, T. A. Korotkova, T. A. Popova, M. L. Sukhareva, E. A. Taskina, V. N. Khodyrev, E. P. Sharapova, A. G. Solodovnikov, A. A. Vlasov

“…Dynamic electroneurostimulation (DENS) is a type of percutaneous electroneurostimulation with a differentiation approach to choosing exposure areas and to optimizing electrocutaneous therapeutic action on the reflexogenic areas and acupuncture points for analgesia and for the treatment of functional disorders.Objective: to study the clinical efficiency and safety of therapy using a DiaDENS-PC apparatus in the treatment of knee osteoarthritis (OA).Subjects and methods. A multicenter randomized double-blind placebo-controlled study was conducted in 132 knee OA patients with pain value above 40 mm on visual analogue scale (VAS) and Lequesne’s index of 4–12. …”
Get full text