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21601
Comparison of extracorporeal shockwave therapy, ultrasound therapy, and corticosteroid injections for treatment of lateral epicondylitis: an umbrella review of meta-analyses
Published 2025-08-01“…Abstract Background The purpose of this study was to assess the methodological quality of meta-analyses (MAs) and resolve evidence inconsistencies by quantifying overlap in primary studies, thereby providing enhanced evidence on the efficacy of extracorporeal shockwave therapy (ESWT) versus placebo, ultrasound therapy, and corticosteroid injections for lateral epicondylitis. Methods We conducted searches in four databases: PubMed, Embase, Cochrane Library, and Web of Science, until August 2024. …”
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21602
Citizen Worry and Adherence in Response to Government Restrictions in Switzerland During the COVID-19 Pandemic: Repeated Cross-Sectional Online Surveys
Published 2025-01-01“…ObjectiveThis study aimed to evaluate worries in the Swiss population as well as associations between worry levels and citizens’ adherence to government restrictions during different phases of the COVID-19 pandemic. MethodsWe carried out an observational study with 4 cross-sectional online surveys of adults in the Canton of Vaud, Switzerland. …”
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21603
Investigation of the analgesic efficacy of local therapy with non-steroidal anti-inflammatory drugs in patients with knee osteoarthritis
Published 2024-10-01“…Objective: to analyze the extent of analgesic effect and to determine predictors of inadequate response to local therapy with non-steroidal antiinflammatory drugs (NSAIDs) in a prospective, comparative, randomized trial of the efficacy and safety of Artoxan® gel 1% versus Diclofenac gel 1% in patients with knee OA.Material and methods. The study included 60 patients with a definite diagnosis of stage II–III Kеllgren–Lawrence knee OA who fulfilled ACR criteria and were observed on an outpatient basis in V.A. …”
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21604
Impact of Endovascular Revascularization on Functional Connectivity and Cognition in Symptomatic Chronic Internal Carotid Artery Occlusion Patients: A Preliminary Exploratory Study
Published 2025-04-01“…We explored alterations in functional connectivity (FC) and their associations with cognition in patients with symptomatic CICAO before and after carotid revascularization. Methods: Eighteen patients with unilateral CICAO and fifteen healthy controls (HCs) were enrolled. …”
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21605
Effects of a Digital Functional Exercise Program on the Disease Activities and Physical Capabilities of Patients With Ankylosing Spondylitis: Protocol for a Randomized Controlled T...
Published 2025-07-01“…ObjectiveThis study aims to evaluate the feasibility and efficacy of a Digital Functional Exercise Program (DFEP) using wearable sensors and real-time feedback for patients with AS. MethodsThis single-blind randomized controlled trial (ChiCTR2300068327) enrolled 80 adults with AS from the Chinese People’s Liberation Army (PLA) General Hospital. …”
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21606
Linguistic Markers of Pain Communication on X (Formerly Twitter) in US States With High and Low Opioid Mortality: Machine Learning and Semantic Network Analysis
Published 2025-05-01“…We also evaluated the predictive power of these linguistic features using machine learning and identified key thematic structures through semantic network analysis. MethodsWe collected 1,438,644 pain-related tweets posted between January and December 2021 using tweepy and snscrape. …”
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21607
The effects of rhythm control strategies versus rate control strategies for atrial fibrillation and atrial flutter: A systematic review with meta-analysis and Trial Sequential Anal...
Published 2017-01-01“…Our objective was to assess the beneficial and harmful effects of rhythm control strategies versus rate control strategies for atrial fibrillation and atrial flutter.<h4>Methods</h4>We searched CENTRAL, MEDLINE, Embase, LILACS, Web of Science, BIOSIS, Google Scholar, clinicaltrials.gov, TRIP, EU-CTR, Chi-CTR, and ICTRP for eligible trials comparing any rhythm control strategy with any rate control strategy in patients with atrial fibrillation or atrial flutter published before November 2016. …”
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21608
Dexmedetomidine versus Dexamethasone as an Adjuvant to Ropivacaine in Transversus Abdominis Plane Block in Infraumbilical Surgeries for Postoperative Analgesia: A Randomised Clinic...
Published 2025-01-01“…Aim: To compare the duration of analgesia (the time of first rescue analgesia) and the quality of pain relief, as assessed by the Visual Analogue Scale (VAS), between dexmedetomidine and dexamethasone as adjuvants to ropivacaine in the TAP block for infraumbilical surgeries. …”
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21609
Experience of using zonisamide in children in routine clinical practice (a multicenter study)
Published 2024-07-01“…To assess the efficacy, tolerability, and continuation of zonisamide (Zonegran) therapy in children with epilepsy.Materials and methods. This retrospective multicenter study was conducted in epileptology centers in various regions of the Russian Federation, including Moscow, Novosibirsk, Krasnodar, Tyumen, Krasnoyarsk, Voronezh, Ryazan). …”
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21610
Pooled prevalence and multilevel determinants of stillbirths in sub-Saharan African countries: implications for achieving sustainable development goal
Published 2025-02-01“…In light of these statistics and the need to address the lack of data, methodological approaches, and population gaps, this study aims to assess the prevalence and determinants of stillbirths in SSA from 2016 to 2023, aligning with the SDGs. Methods This study used data from the Demographic and Health Survey (DHS) conducted in SSA. …”
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21611
Ultrasound-guided injection of platelet-rich plasma alleviated pain and improved function for individuals with myofascial pain syndrome: a retrospective case series study
Published 2025-07-01“…Primary outcome was pain quantified by the Visual Analog Scale (VAS) and the McGill Pain Questionnaire (McGill). …”
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21612
The effect of acute beetroot juice consumption prior to climbing on lower-body isokinetic and isometric strength, aerobic power, and muscle soreness among mountain climbers
Published 2025-12-01“…Thus, the present study aimed to investigate the effect of consuming beetroot juice acutely before climbing on lower-body isokinetic and isometric strength, aerobic power, and muscle soreness in mountain climbers.Methods In a randomized, placebo-controlled, double-blinded study, 27 climbers (14 males and 13 females) were divided into three groups: Control (CON), Placebo (PLA), and Beetroot Juice (BRJ), with 9 participants in each group. …”
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21613
P253 Next-generation phenotyping facilitates the identification of structural brain malformations in rare disorders through computational brain MRI analysis
Published 2025-01-01“…In this work, we propose a deep learning-based NGP approach to detect brain malformations and their associated disorders, providing clinicians with diagnostic support and enabling integration into variant prioritization pipelines. Methods: We curated a dataset of 413 brain MRI images from publications and clinicians, covering 56 different disorders, and stored it in the GestaltMatcher Database (GMDB). …”
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21614
The results of investigating the efficacy and safety of non-medical switching from the original rituximab to its biosimilar in rheumatoid arthritis patients (AMBIRA study)
Published 2021-01-01“….”, Switzerland) to its biosimilar (Acellbia®, “BIOCAD”, Russia) by non-medical reasons in rheumatoid arthritis patients.Subjects and methods. 40 rheumatoid arthritis patients on basic therapy who had taken at least one course of original rituximab (MabThera®) 1000 mg twice in 2 weeks more than 6 months ago were included. …”
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21615
Comorbidity in patients with lobular panniculitis-lipodermatosclerosis
Published 2021-06-01“…The onset of LDS falls on the age of 50–60 years, when many patients already have comorbid pathology requiring complex therapy, which affects the course, the choice of treatment and prognosis of LDS, as well as the quality of life.Objective: to study the structure and frequency of comorbid conditions in patients with LDS.Patients and methods. 53 patients (3 men and 50 women), 18–80 years old, with a verified diagnosis of LDS were included, all of them had an average follow up of 10 years (they were observed in the V.A. …”
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21616
Transverse process-pedicle approach versus conventional transpedicular approach in percutaneous kyphoplasty for osteoporotic vertebral compression fracture
Published 2025-08-01“…The aim of this study was to investigate the clinical advantages of PKP via TPPA for the treatment of OVCF, by comparing it with the conventional transpedicular approach (CTPA). Methods A retrospective study was conducted to analyze data from 124 patients with single-segment OVCF who were treated in our department between January 2019 and December 2022. …”
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21617
EVALUATION OF THE EFFICACY AND SAFETY OF A GLYCOSAMINOGLYCAN-PEPTIDE COMPLEX IN THE TREATMENT OF KNEE OSTEOARTHRITIS IN PATIENTS WITH PREVIOUS INEFFICIENCY OF SLOW-RELEASE ORAL ANT...
Published 2018-03-01“…Objective: to evaluate the efficacy and tolerability of GPC in patients with knee OA, in whom other SRIAs have been previously ineffective.Subjects and methods. A study group consisted of 104 patients (92.3% women) (mean age, 63.2±8.5 years; body mass index (BMI), 28.5±5.4 kg/m2) with severe joint pain (≥40 mm on a 100-mm visual analogue scale (VAS)) and/or the need to regularly use nonsteroidal anti-inflammatory drugs (NSAIDs). …”
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21618
Validation of the Russian-language version of the ASAS Health Index
Published 2019-07-01“…The questionnaire contains 17 questions, each of which is associated with a specific ICF pool (pain, emotions, sleep, sexual function, ambulation, self-care, and communication).Objective: to study the psychometric properties of the Russian-language version of ASAS HI.Subjects and methods. Examinations were made in 245 patients older than 18 years with axSpA or peripheral SpA, who met the ASAS criteria. …”
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21619
Effect of low-intensity resistance training at different levels of blood flow restriction on pain, proprioception and muscle strength in patients with knee osteoarthritis: a random...
Published 2025-08-01“…This study seeks to evaluate the effects of LIRT at varying BFR levels on pain, proprioception, and muscle strength in KOA patients. Methods A total of 100 KOA patients were randomly assigned to four groups: LIRT, LIRT + BFR30%, LIRT + BFR50%, and LIRT + BFR80%. …”
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21620
Perceptual Decision Efficiency Is Modifiable and Associated with Decreased Musculoskeletal Injury Risk Among Female College Soccer Players
Published 2025-07-01“…Immersive virtual reality (VR) systems can measure the speed, accuracy, and consistency of body movements corresponding to stimulus–response instructions for the completion of a forced-choice task. <b>Methods</b>: A cohort of 26 female college soccer players (age 19.5 ± 1.3 years) included 10 players who participated in a baseline assessment, 10 perceptual-response training (PRT) sessions, a post-training assessment that preceded the first soccer practice, and a post-season assessment. …”
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