SUN-domain proteins of the malaria parasite Plasmodium falciparum are essential for proper nuclear division and DNA repair by Sofiya Kandelis-Shalev, Manish Goyal, Tal Elam, Shany Assaraf, Noa Dahan, Omer Farchi, Eduard Berenshtein, Ron Dzikowski

“…However, while the nuclear periphery of P. falciparum was implicated in several important functions, the role of the LINC complex in Plasmodium biology is unknown. …”
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A feedback circuitry involving γ-actin, β-actin and nonmuscle myosin-2 A controls tight junction and apical cortex mechanics by Marine Maupérin, Yuze Sun, Thomas Glandorf, Tabea Anne Oswald, Niklas Klatt, Burkhard Geil, Annick Mutero-Maeda, Isabelle Méan, Lionel Jond, Andreas Janshoff, Jie Yan, Sandra Citi

“…Abstract Cytoplasmic β- and γ-actin isoforms, along with non-muscle myosin 2 isoforms, are tightly regulated in epithelial cells and compose the actomyosin cytoskeleton at the apical junctional complex. …”
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Two-group bubble size distribution evolution in vertical two-phase flow: Mechanistic model development and evaluation in a tight-lattice rod bundle by Xiao Yao, Zhang Hengwei, Yan Xu, Gu Hanyang

“…Two-phase flow with complex phase interfaces is commonly observed in both nature and industrial processes. …”
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Perfect Roman Domination: Aspects of Enumeration and Parameterization by Kevin Mann, Henning Fernau

“…We also consider the enumeration of minimal Perfect Roman Dominating Functions and show a tight relation to minimal Roman Dominating Functions. …”
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Tannic Acid and Ethacridine Lactate Attenuate Markers of Stress-Induced Intestinal Barrier Dysfunctions in Murine Small Intestinal Organoids by Louisa Filipe Rosa, Steffen Gonda, Nadine Roese, Stephan C. Bischoff

“…(1) Background: Tannacomp^® is a drug consisting of tannin albuminate, a complex of tannic acid (TA) and ethacridine lactate (Eta) used for treating acute and traveler’s diarrhea. …”
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Restoring brain barriers: an innovative approach for treating neurological disorders by Sighild Lemarchant, Britta Engelhardt, Francesca Cicchetti, Gregory J. Bix, Annette Janus, Yann Godfrin, Hélène Blasco, Matthew Campbell, Aurélie de Rus Jacquet

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Exofection by exosomes: A transient functional cargo transfer by Ramkumar Menon, Madhuri Tatiparthy, Jessica Selim, Isidore Mushimiyimana, Brinley Harrington, Awanit Kumar, Lauren Richardson, Emmanuel Amabebe, Ananth Kumar Kammala

“…For instance, mitochondria-containing EVs from brain endothelial cells restore mitochondrial function and tight junction integrity in ischemic brain tissues. …”
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Maturation of small nucleolar RNAs: from production to function by Sarah F. Webster, Homa Ghalei

“…Besides their classic roles in ribosome biogenesis, snoRNAs are also implicated in several other cellular activities including regulation of splicing, transcription, RNA editing, cellular trafficking, and miRNA-like functions. Mature snoRNAs must undergo a series of processing steps tightly regulated by transiently associating factors and coordinated with other cellular processes including transcription and splicing. …”
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Impact of viral disease hypophagia on pig jejunal function and integrity. by Emma T Helm, Shelby M Curry, Carson M De Mille, Wesley P Schweer, Eric R Burrough, Nicholas K Gabler

“…Further, long term adaptation to PRRSV challenge and caloric restriction does reduce intestinal transepithelial resistance but does not appear to reduce the integrity of tight junction protein complexes.…”
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IgSF11–RAP1 signaling promotes cell migration and invasion of cutaneous melanoma by Yasuyuki Kobayashi, Kotaro Sugimoto, Minaka Ishibashi, Makoto Kobayashi, Shohei Igari, Shigeki Kitamura, Toshiyuki Yamamoto, Yuko Hashimoto, Hideki Chiba

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The Functional State of Meibomian Glands and Tear Production in Pregnant Women by V. N. Trubilin, E. G. Poluninа, D. V. Andzhelova, Yu. V. Evstigneeva, K. V. Chinenova

“…It makes temporary changes in the functional state of all  organs and systems, including the organ of vision. …”
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Arecoline regulates glycolipid and endoplasmic reticulum metabolisms in adult grass carp (Ctenopharyngodon idella) by Liangqin Wu, Na Yao, Weidan Jiang, Pei Wu, Yang Liu, Yaobin Ma, Hongmei Ren, Xiaowan Jin, Hequn Shi, Xiaoqiu Zhou, Lin Feng

“…Secondly, arecoline protected mitochondrial function by promoting the mitochondrial respiratory chain complex I–V-related protein expression and triggering the mitochondrial unfolded protein response (UPRmt) (P < 0.05). …”
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Two Functional TP53 Genetic Variants and Predisposition to Keloid Scarring in Caucasians by Andrzej Dmytrzak, Agnieszka Boroń, Beata Łoniewska, Klaudyna Lewandowska, Iwona Gorący, Mariusz Kaczmarczyk, Andrzej Ciechanowicz

“…The pathogenesis of keloid is complex, and many evidences suggest the influence of genetic factors, among them the polymorphisms of the TP53 gene encoding tumor protein p53. …”
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Simulating Marine Ecosystem Dynamics and Biogeochemical Cycling With Multiple Plankton Functional Types by Jun Yu, Kristen M. Krumhardt, J. Keith Moore, Robert T. Letscher, Shanlin Wang, Nicola A. Wiseman, Matthew C. Long, Keith Lindsay, Michael Levy, Colleen M. Petrik, Adam C. Martiny

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Integration of Quality Function Deployment and TRIZ Methodologies to Design a Sanitary Part by Dino Caesaron, Farell Ardani, Vidhea Nurhadi, Yusuf Yekti

“…The main objective of this study was to create the design of specific machining sanitary Spare Parts production due to complexity of the design. In the proposed methodology, Quality Function Deployment is used to convert the subjective requirements from users into an objective technical response. …”
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Probiotics improve intestinal oxidative stress to protect intestinal barrier function in uremic rats by WEI Meng, JIANG Hong-li, SHI Ke-hui, WANG Meng, SUN Ling-shuang, HE Quan

“…Objective To investigate whether oral probiotic Bifidobacterium animalis subsp.Lactis Bi-07 protects the intestinal barrier function of uremic rats,and explore whether it plays its biological effects by improving oxidative stress in tissues.Methods Thirty SD rats were randomly divided into 3 groups(n=10),sham operation group,uremic group,uremia + probiotic group.For the sham operation group only the renal capsule was opened,and for the uremic group 5/6 nephrectomy was conducted.For the uremia + probiotic group 5/6 nephrectomy was performed and then the animals were administered with Bi-07 every day for 4 weeks.The rats were anesthetized and the jejunum,ileum and colon segments were taken out.The ultrastructure of the intestinal epithelial tight junction complex was observed by scanning electron microscopy combined with lanthanum nitrate staining.The intestinal homogenate was prepared,and malondialdehyde(MDA) content was determined by thiobarbituric acid condensation method;and superoxide dismutase(SOD) activity was determined by xanthine oxidase method.Results Compared with the uremic group,supplement of probiotics could restore the tight junction ultrastructure between epithelial cells,with neat microvilli and intact structure.Compared with the uremic group,the intestinal permeability in the uremia + probiotic group was significantly decreased(P<0.05);serum inflammatory factors hs-CRP,IL-6,TNF-α levels were significantly lower(P<0.05);the intestinal SOD level was significantly increased(P<0.05);and the intestinal MDA showed a decreasing trend,but the difference was not statistically significant(P>0.05).Conclusions Bi-07 can improve intestinal barrier function in uremic rats.The mechanism may be realized by inhibiting intestinal oxidative stress so as to reduce intestinal barrier damage in uremic rats.…”
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The influence of the choroid plexus on brain function: beyond its role in cerebrospinal fluid production by Sayako Katada, Kelren S. Rodrigues, Kinichi Nakashima

“…Traditionally recognized for its primary role in cerebrospinal fluid (CSF) production, recent research has unveiled a far more complex and dynamic picture of the ChP’s contributions to brain health and homeostasis. …”
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Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis. by Radhika Mathur, James L Yen, Peter Kaiser

“…More importantly, our results assign important biological functions to a sub-complex of cullin-RING ligases that comprises Cdc53/Rbx1/Cdc34, but is independent of Skp1.…”
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Neural Mechanisms and Alterations of Sweet Sensing: Insights from Functional Magnetic Resonance Imaging Studies by Tobias Long, Colette C. Milbourn, Alison Smith, Kyaw Linn Su Khin, Amanda J. Page, Iskandar Idris, Qian Yang, Richard L. Young, Sally Eldeghaidy

“…By integrating current evidence, this review advances our understanding of the complex interplay between sweet sensing, brain responses, and health and identifies key gaps and directions for future research in nutritional neuroscience.…”
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Development of nanofiber facial mask inspired by the multi-function of dried ginger (Zingiberis Rhizoma) essential oil by Yiwen Hao, Xia Lin, Wenwen Liu, Tinghongyang Jiang, Xing Zhang, Shasha Yang, You Huang, Wenjing Lai, Chaomei Fu, Zhen Zhang

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