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5241
L-glutaminase synthesis by Klebsiella pneumoniae (AS KP 23) isolated from clinical strain, and its efficacy against human hepatocellular and breast cancer cell lines
Published 2025-02-01“…The 16 S rRNA gene was 100% identical to the sequence from Klebsiella pneumoniae and was submitted to GenBank under accession number OQ703039. Thus, this strain was named Klebsiella pneumoniae AS KP 23. …”
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5242
Assessment of Bowel Preparation Using Low-Volume Sulphate-Based Preparations in Comparison with Macrogols: A Multicenter, Randomized, Comparative Clinical Study of the 3rd Phase
Published 2019-05-01“…The authors also express their appreciation to Olga Kapitonova, an employee of the Almedis company (Moscow, Russia) for her assistance in compiling medical texts, which activity was carried out under the financial support of the Ipsen company (Moscow, Russia) in accordance with the Good Publication Practice (GPP).…”
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5243
Modeling Portfolio Optimization based on behavioral Preferences and Investor’s Memory
Published 2024-03-01“…We employ a Genetic Algorithm (GA) to optimize portfolios under both criteria. GA is a robust optimization technique that can effectively handle complex problems with multiple constraints. …”
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5244
Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis
Published 2025-02-01“…A history of diabetes for over 10 years was strongly associated with non-use for DCD lungs (OR, 0.87, P = 0.71), whereas an under 10-year history was associated with increased use (OR 2.33, P = 0.008, OR 1.07 P = 0.819).Lungs from donors ages 40–49 are more likely to be procured than those <30 or >50 in both DBD and DCD. …”
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5245
Inflammatory Gene Signature Identified by Machine Algorithms Reveals Novel Biomarkers of Coronary Artery Disease
Published 2025-02-01“…Then, the receiver operating characteristic (ROC) curves were plotted for each DIRG, and those with an area under the curve (AUC) greater than 0.9 were selected for subsequent analysis. …”
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5246
Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy
Published 2025-02-01“…This material, termed CaO2@ZIF8:CUR@PAA, comprises a CaO2 core coated with the ZIF-8 framework, which was then loaded with curcumin (CUR) and coated again with polyacrylic acid (PAA).Results: Under the slightly acidic conditions of the TME, the PAA shell (first lock) breaks down first exposing CaO2@ZIF8 and CUR inside the cell. …”
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5247
The diagnostic value of the combined application of blood lipid metabolism markers and interleukin-6 in osteoporosis and osteopenia
Published 2025-02-01“…Additionally, the osteoporosis group presented substantially higher levels of ApoA1, FFAs, and IL-6 than the osteopenia group. (4) IL-6 was positively correlated with FFAs, while a negative correlation was observed with TC, ApoA1, ApoB, HDL-C, and LDL-C. (5) The ROC curve revealed that the areas under the curve (AUCs) of TC, FFAs, IL-6, ApoA1, and the ApoA1/ApoB ratio for predicting osteoporosis or osteopenia were 0.634, 0.713, 0.670, 0.628, and 0.516, respectively, whereas the AUC of the combination of TC, FFAs, IL-6, and ApoA1 was 0.846, and the AUC of the combination of TC, FFAs, IL-6, and the ApoA1/ApoB ratio was 0.842. …”
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5248
IGJR 1/2020: Housing crisis: How can we improve the situation for young people?
Published 2018-12-01“…Its editorial board consists of about 50 internationally renowned experts from ten different countries. IGJR is indexed under Directory of Open Access Journals (DOAJ). …”
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5249
Phenomenology of Organizational Silence (Case Study Farhangian University)
Published 2024-09-01“…Gender discrimination in the delegation of authority, lack of promotion based on merit, lack of recruitment and employment based on openness and creativity, absence of a meritocracy, lack of appreciation for employees' efforts, and job insecurity were grouped under the human resources theme. The supervision and control theme revealed that securitization of the work environment, emphasis on employee control, university control processes, external regulatory bodies, and the silent punishment and marginalization of employees are significant factors. …”
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5250
Evaluation de la qualité de vie des femmes souffrant d’une fistule obstétricale à Kinshasa [Evaluation of the quality of life of women with obstetric fistula in Kinshasa]
Published 2023-06-01“…Results -In terms of socio-demographic variables, the study sample consisted of 20 women under the age of 30, 15 aged 30-39 and 21 aged 40-49. …”
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5251
Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway
Published 2025-02-01“…Pathway-related protein inhibitors (the autophagy-related inhibitor 3-methyladenine (3-MA), chloroquine (CQ), ROS inhibitor N-acetyl-L-cysteine (NAC) were applied, and autophagosome changes were observed under transmission electron microscopy. Immunofluorescence was used to observe LC3 spot formation within cells. …”
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5252
Evaluation of Dynamic Visual Perception of Riverside Interface in Mountainous Cities from the Perspective of Boating
Published 2025-02-01“…The research on the dynamic visual perception of urban interface from the perspective of boating can provide a theoretical basis for the control and improvement of visual landscape in mountainous cities.MethodsTaking the riverside interface of the core area of “Two Rivers and Four Banks” in Chongqing as the research object and the cruise line of Liangjianghui as the movement path, this research connects the perception state and spatial characteristics by combining subjective and objective evaluation indicators, and analyzes the underlying logic of the formation of visual perception results. …”
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5253
Construction of Multi-level Ecological Corridor System for National Parks: A Case Study of the Proposed Nanling National Park
Published 2025-02-01“…The research simulates the distribution of ecological source areas under different future scenarios, delineates construction management and control zones, and formulates specific implementation measures. …”
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5254
Life Cycle Assessment (LCA) of Carbon Emission of Garden Pavement
Published 2025-01-01“…Among the 25 types of pavements, granular pavement of graded gravel surface without cementation performs best in environmental adaption, environmental protection and low carbon, and thus can be vigorously promoted for use under appropriate conditions.…”
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5255
Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone
Published 2025-01-01“…Furthermore, highly correlated LCZ types are screened out under the optimal size, the multicollinearity of all LCZ landscape pattern indices is examined and those with multicollinearity are excluded. …”
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5256
Integrated Framework and Technical Path for Multi-level Nested Assessment of Landscape Character
Published 2025-01-01“…Based on existing research content, the research summarizes the overall characteristics and future development trends of the two assessment methods, analyzes the differences and underlying connections between them, and explores possible integration methods for them.ResultsLCA can describe what a landscape is, while LPA can explore why it is. …”
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5257
Influencing Mechanisms of Ecosystem Services on Net Carbon Sink Efficiency and Spatial Differentiation Thereof: A Case Study of the Shanghai Metropolitan Area
Published 2025-01-01“…While effectively coordinating regional ecological, social and economic needs and promoting carbon sequestration and emission reduction, ecosystem services can be transmitted to surrounding areas to boost regional ecological space optimization. Under the guidance of the carbon peaking and carbon neutrality goals, clarifying the positive impact of ecosystem services on net carbon sink efficiency in metropolitan areas and the spillover effect of ecosystem services can effectively contribute to regional ecosystem service enhancement, and realize efficient carbon sequestration and reduction in ecological space.MethodsSupported by multi-source panel data spanning the period from 2010 to 2020, this research takes the Shanghai Metropolitan Area as the research object and divides the research area into 40 research units. …”
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5258
Psychosocial risks and mental health of health and social care workers in the context of the COVID-19 pandemic
Published 2024-07-01“…Many of us may experience another pandemic, arising under the current scenarios of climate alterations leading to disease vectors spreading in new areas, the return of old ones, and aggravated human transmission pathways. …”
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5259
Visual Environment Factors Influencing Staying Behaviors During Cycling on Countryside Greenways
Published 2025-02-01“…Since visual perception accounts for 80%-90% of the information humans receive from their environment, it exerts a profound influence on human behavior and environmental experiences. Riders on countryside greenways are often attracted to the distinctive visual environments and tend to make spontaneous stops, which could increase safety risks. …”
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5260
Impact de l’évaluation de la sédation sur la durée de ventilation mécanique en réanimation pédiatrique [Impact of sedation assessment on duration of mechanical ventilation in pedia...
Published 2023-06-01“…Methods-: This is a monocentric comparative study of before- and-after practice evaluations,conducted in the paediatric intensive care unit of the Canastel paediatric hospital in Oran.The comparative study was conducted over two periods, the first from 2014 to 2016 without a sedation assessment protocol and the second from 2017 to 2019 after the introduction of a sedation assessment protocol based on the COMFORT-B scale. All children under 15 years of age who were ventilated and sedated for 24 hours or more were included in the study. …”
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