FEDERALISM, INSECURITY, AND THE PERSISTENT AGITATIONS AMONG ETHNIC GROUPS IN NIGERIA’S FOURTH REPUBLIC: ANY WAY FORWARD? by TEMITOPE EMMANUEL ABIODUN, IBRAHIM ADEDAYO OYEWOLE, ENOCH AKINLOLUWA MAKINDE

“…Federalism have been largely accepted as the better form of government in a heterogeneous society such as Nigeria, however, the kind of federal system operating in Nigeria has created many problems because diverse ethnic and religious groups are unceremoniously brought together under one umbrella. The paper made used of qualitative approach and adopted group and frustration-aggression theories as its theoretical framework. …”
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CD8+T cells and monocytes were associated with brain alterations in human immunodeficiency virus-infected individuals with cognitive impairment by Xin Zhang, Zhen Li, Jiahao Ji, Yundong Ma, Guangqiang Sun, Xue Chen, Ling Zhang, Tong Zhang, Yulin Zhang, Yang Zhang

“…Cognitive impairment (CI) continues to be a concern for people living with HIV-1 (PLWH) in the era of antiretroviral therapy (ART), yet the underlying mechanisms remain unclear. We aimed to elucidate the structural and functional brain alterations and peripheral immune profile of PLWH with CI, as well as the correlation between them. …”
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Self-adaptive fuzzing optimization method based on distribution divergence by XU Hang, JI Jiangan, MA Zheyu, ZHANG Chao

“…An interprocedural comparison flow graph was first constructed based on the interprocedural control flow graph to characterize the spatial random field corresponding to the branch condition variables of the program under test, and the distribution features of the random field generated by a fuzzing mutation strategy were extracted using the Monte Carlo method. …”
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How to survive the mutational meltdown: lessons from plant RNA viruses by Lafforgue, Guillaume, Lefebvre, Marie, Michon, Thierry, Elena, Santiago F.

“…We observed three distinct evolutionary outcomes for tobacco etch virus under three different demographic conditions: (i) a decline in fitness following periodic severe bottlenecks in Chenopodium quinoa, (ii) a consistent fitness level with moderate bottlenecks in C. quinoa, and (iii) a net increase in fitness when severe bottlenecks in C. quinoa were alternated with large population expansions in Nicotiana tabacum. …”
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A growing degree day model determines the effect of temperature stress on diverse chickpea genotypes by Cara Jeffrey, Cara Jeffrey, Cara Jeffrey, Laura Ziems, Laura Ziems, Brent Kaiser, Brent Kaiser, Richard Trethowan, Richard Trethowan

“…It was also determined that loss of yield and a decrease in seed size was significantly correlated with high GDD and SDD, though seed size had less environmental plasticity (variability) compared to yield, and therefore higher stability under stress. GDD and SDD were shown to be useful for predicting genotype adaptation to locations and seasons thus providing a basis for varietal recommendations. …”
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Long-Term Results of the Etiotropic Therapy of Subcompensed Liver Cirrhosis in the Outcome of Chronic Hepatitis C by P. O. Bogomolov, A. O. Bueverov, V. E. Bakirova, E. O. Lyusina, E. A. Fedosyina, S. V. Koblov, O. V. Sumtsova

“…Longterm follow-up results indicate a significant improvement of liver function, but also a continuing high risk of developing complications of underlying disease, primarily HCC.…”
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The impact of Kersen leaves (Muntingia calabura L.) extract on Mus musculus with hypercholesterolemia by Sion Benu, Anita Amat, Arley Telussa, Rr Listyawati Nurina

“…Further research is necessary to elucidate the underlying mechanisms of action and evaluate its clinical applicability. …”
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On small Dirac neutrino masses in string theory by Gonzalo F. Casas, Luis E. Ibáñez, Fernando Marchesano

“…In this regime we find Dirac neutrino masses of the form m ν ≃ g ν ⟨H⟩, with g ν the gauge coupling of the massive U(1) under which the right-handed neutrinos ν R are charged, and which should be in the range g ν ≃ 10 −14 − 10 −12 to reproduce neutrino data. …”
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Pleiotropic effects of a recessive Col1a2 mutation occurring in a mouse model of severe osteogenesis imperfecta. by Michelangelo Corcelli, Rachel Sagar, Ellen Petzendorfer, Mohammad Mehedi Hasan, Fleur S van Dijk, Anna L David, Pascale V Guillot

“…Together, these findings identify the complex mechanisms underlying OI bone fragility in the OIM model of severe OI and can potentially enable identification of clinically relevant endpoints to assess the efficacy of innovative pro-osteogenic treatment for patients with OI.…”
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Development of a high-order global dynamical core using the discontinuous Galerkin method for an atmospheric large-eddy simulation (LES) and proposal of test cases: SCALE-DG v0.8.0 by Y. Kawai, H. Tomita, H. Tomita

“…In the LES experiment, the global model provided a reasonable vertical structure of the PBL and energy spectra because the results under shallow-atmosphere approximation reproduced those obtained in the plane computational domain well.…”
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Efficacy of natural killer T and gammadelta T cells in mesothelin-targeted immunotherapy of pancreatic cancer by Yuankui Zhu, Yaxi Yang, Linghe Yue, Lei Wan, Xuqian Ma, Qing Yang, Xuan Tian, Yuguan Li, Ke Wang, Shaozhong Wei, Shaozhong Wei, Shaozhong Wei, Dianbao Zuo, Mingqian Feng, Mingqian Feng

“…This study demonstrated that MSLN/CD3 BsAb effectively activated and recruited PBMCs, NKT and γδT. Furthermore, under the influence of MSLN/CD3 BsAb, γδT and NKT cells exhibited notably superior anti-tumor activity compared to PBMCs, both in vitro and in vivo, while demonstrating low cytokine release. γδT cells showed almost negligible toxic side effects. …”
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Microplastic exposure induces HSP90α secretion and aggravates asthmatic airway remodeling via PI3K-Akt-mTOR pathway by Mingming Xu, Jiyuan Chen, Lin Gao, Shaoxi Cai, Hangming Dong

“…Microplastics can enter the human respiratory system, then deposit in the lung, destroying the structure of the bronchus and alveoli, and causing pulmonary inflammation, mucus production, and airway hyperresponsiveness, leading to the aggravation of asthma. Nevertheless, the underlying mechanism remains elusive. There are several cytokines involved in the inflammatory response of asthma. …”
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Biodiversity characteristics of large forest plots in Qinghai area of Qilian Mountain National Park by WANG Dinghui, SUONAN Cairang, YU Hongyan, DU Yangong

“…[Objective] Long-term monitoring of plant community dynamics in large forest plots helps reveal the spatial patterns and underlying mechanisms that sustain species diversity. …”
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The same but different. Multidimensional assessment of depression in students of natural science and music by Michaela Korte, Deniz Cerci, Roman Wehry, Renee Timmers, Victoria J. Williamson

“…This study used a predictive design, observing the change in variables between groups as well as predicting which combinations of variables would likely determine depression prevalence. 102 under- and postgraduate students from various higher education institutions participated in an online survey. …”
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Peering into the Black Box: Forward Modeling of the Uncertainty Budget of High-resolution Spectroscopy of Exoplanet Atmospheres by Arjun B. Savel, Megan Bedell, Eliza M.-R. Kempton, Peter C. B. Smith, Jacob L. Bean, Lily L. Zhao, Kaze W. K. Wong, Jorge A. Sanchez, Michael R. Line

“…This tool allows us to control the underlying data set, enabling controlled experimentation with complex HRCCS methods. …”
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Redox-mediated reverse water gas shift integrated with ammonia cracking over Ni/La0.75Sr0.25Cr0.5Mn0.5O3−δ by Martin Keller, Shih-Yuan Chen, Atul Sharma

“…Therefore, the process is best implemented at ∼600 °C. Under these conditions, the application of the “NH3-RWGS” process with mixtures of LSCM and Ni catalyst is promising to produce high-quality, N2-free syngas directly from NH3 and CO2.…”
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Current molecular understanding of central nervous system schwannomas by Takahiro Tsuchiya, Satoru Miyawaki, Yu Teranishi, Kenta Ohara, Yudai Hirano, Shotaro Ogawa, Seiei Torazawa, Yu Sakai, Hiroki Hongo, Hideaki Ono, Nobuhito Saito

“…Although our understanding of the molecular biology underlying schwannomas remains incomplete, numerous studies have identified various molecular findings and biomarkers associated with schwannomas of the central nervous system (CNS). …”
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TMEM97 governs partial epithelial-mesenchymal transition of retinal pigment epithelial cells via the CTNND2-ADAM10 axis by Jing Li, Yosuke Nagasaka, Hongtao Shen, Xinyu Zhou, Jianjie Ma, Dilza Trevisan-Silva, Nicholas E. Sherman, Jayakrishna Ambati, Bradley D. Gelfand, Lian-Wang Guo

“…Here, we link TMEM97 to pEMT in RPE cells and explore the underlying molecular mechanisms. We found that re-expressing TMEM97 in the RPE of TMEM97-knockout mice, via subretinal lentiviral delivery, mitigated oxidant (NaIO3)-induced photoreceptor loss. …”
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Comparison of a combined torus tank with a composite isogrid support with existing design solutions by Andrii Diadiuk, Volodymyr Lipovskyi

“…In this work, we determine the parameters and weight of the combined tanks under prototype load conditions using the engineering method of calculating the efficient torus tank with isogrid composite reinforcement. …”
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Clinical Course of Untreated and Treated Chronic Hepatitis B in Pregnant Patients: A Prospective Study by Yasemin Nadir, Ayse Batirel, Ayse Yasemin Karsidag, Fatma Kaya Narter, Ahmet Nadir

“…RESULTS: The risk factors for transmission (HBeAg positivity, history of previously-born HBsAg-positive child) were significantly higher in the treated group. All participants under treatment had sufficient viral suppression. …”
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