3,5,6,7,8,3’,4’- Heptamethoxyflavonoid inhibits TGF-β1-induced epithelial–mesenchymal transition by regulating oxidative stress and autophagy through MEK/ERK/PI3K/AKT/mTOR signalin... by Yiting Wang, Zhiheng Ma, Weiwen Peng, Qinglian Yu, Wenjie Liang, Liu Cao, Zhuqiang Wang

“…However, it remains unclear whether and how HMF alleviates transforming growth factor-β1 (TGF-β1)-induced EMT. …”
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Ficus deltoidea standardized methanolic extract improves kidney structure and function against streptozotocin-induced diabetic nephropathy in rats by Nurdiana Samsulrizal, Noor Syaffinaz Noor Mohamad Zin, Nur Syimal`ain Azmi, Mohd Daud Bakar, Hafandi Ahmad, Yong-Meng Goh

“…However, it remains uncertain whether F. deltoidea could delay the progression of nephropathy. …”
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A theory-based analysis of the implementation of online asynchronous telemedicine platforms into primary care practices using Normalisation Process Theory by Cara Leighton, Natalie Joseph-Williams, Annavittoria Porter, Adrian Edwards, Alison Cooper

“…Abstract Background Online asynchronous telemedicine platforms are effective and have been implemented in primary care practices, but it is unclear whether implementation was successful. Implementation has not been studied on a large scale in primary care practice. …”
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Efficacy and safety of dexamethasone or triamcinolone in combination with anti-vascular endothelial growth factor therapy for diabetic macular edema: A systematic review and meta-a... by Bo Zhou, Hua Liu, Feng Xiong

“…However, it remains uncertain whether the therapeutic benefits of the combined treatment with corticosteroids and anti-VEGFs is superior to those of anti-VEGF monotherapy. …”
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Sexual distress among men with cancer – a cross-sectional study by Jonas Nahavandipour, Christoffer Johansen, Annamaria Giraldi, Bolette Skjøft Rafn, Annika von Heymann

“…However, many studies investigating sexual impairments fail to consider whether such impairments are perceived as distressing, i.e. create sexual distress. …”
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Conservation and ecological screening of small water bodies in temperate riverine wetlands using UAV Photogrammetry (Middle Danube) by Dušanka Cvijanović, Maja Novković, Djuradj Milošević, Milica Stojković Piperac, Laszlo Galambos, Dubravka Čerba, Olivera Stamenković, Bojan Damnjanović, Minučer Mesaroš, Dragoslav Pavić, Vladica Simić, Ivana Trbojević, Ana Anđelković, Nusret Drešković, Barbara Stammel, Bernd Cyffka, Snežana Radulović

“…This paper aims to explore whether UAV-based macrophyte data can provide a more precise indication of the trophic state and conservation indices (assessed through fish and macroinvertebrate communities) of temperate wetland lentic ecosystems, compared to traditional field surveys. …”
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Assessing awareness and treatment knowledge of preventable blindness in rural and urban South African communities by Z Kiva, J E Wolvaardt

“…Proportions were calculated and χ2 tests done to determine whether there was any significant relationship between the categorical variables. …”
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Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B by Qianqian Ma, Junzhao Ye, Ling Luo, Yanhong Sun, Wei Wang, Shiting Feng, Bing Liao, Bihui Zhong

“…However, it is unclear whether different antiviral medications have varying effects on AFP levels. …”
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Efficacy of non-invasive ventilation and oxygen therapy on immunocompromised patients with acute hypoxaemic respiratory failure: protocol for a systematic review and meta-analysis... by Juhong Shi, Gang Liu, Meng Wang, Tao Wang, Yi Li, Yi Yang, Xuezhong Yu, Huadong Zhu, Yong Ma, Zongru Li, Lixi Zhang, Kun He, Jianqiang He

“…This meta-analysis aims to evaluate whether NIV or oxygen therapy is the more appropriate initial oxygenation strategy for the immunocompromised patients with acute respiratory failure.Method We will search all the RCTs that compared the efficacy of NIV and oxygen therapy on immunocompromised adult patients with acute hypoxaemic respiratory failure on the major databases (Cochrane Library, MEDLINE, EMBASE, Web of Science and others), conference proceedings and grey literature. …”
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Efficacy and prognosis of dapagliflozin in the treatment of patients with acute myocardial infarction complicated with type 2 diabetes in Xining area by Jinping Chai, Delian Li, Yanmin Liu, Xiaoling Su

“…The patients were divided into dapagliflozin group and control group according to whether they took dapagliflozin during hospitalization. …”
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Modeling quinoa growth under saline and water-limiting conditions using SWAP-WOFOST by Diana C. Estrella Delgado, Tom De Swaef, Jan Vanderborght, Eric Laloy, Gerda Cnops, Maarten De Boever, Abdelaziz Hirich, Ayoub El Mouttaqi, Sarah Garré

“…The objective of this study was to calibrate the crop growth, and salinity and drought stress parameters of the SWAP – WOFOST model and evaluate whether this model can represent quinoa’s stress tolerance mechanisms. …”
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Germ cell quantification in human fetal and prepubertal testis tissues: a comparison of current methodologies by Emma Kearney, David Greenald, Gabriele Matilionyte, Sheila Lane, Melissa D Tharmalingam, Jill Davies, Jan-Bernd Stukenborg, Grace Forsyth, Rod T Mitchell

“…However, round tubular cross sections are limited in human prepubertal testicular tissues, especially when using in vitro culture. We aimed to assess whether an alternative method of germ cell quantification would provide similar results to recently established methods, without the requirement for round tubules. …”
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UK medical students’ mental health and their intention to drop out: a longitudinal study by Asta Medisauskaite, Antonia Rich, Milou Silkens, Neha Lagisetty

“…It may be useful for medical schools to help applicants/medical students understand whether medical school is the right decision for them and provide them with resources should they wish to leave.…”
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Danish mothers of young children adhere less to international physical activity guidelines compared with mothers of older children by Solvej Videbæk Bueno, Sebastian Deisting Skejø, Rasmus Oestergaard Nielsen, Knud Ryom, Per Kallestrup, Peter Elsborg, Christina Bjørk Petersen, Julie Sandell Jacobsen

“…Additionally, the study aimed to investigate whether such association varied by parity. Methods: The population-based design used self-reported physical activity data on 8774 Danish mothers who participated in the Danish National Health Survey 2021. …”
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The association between TyG index and cardiovascular mortality is modified by antidiabetic or lipid-lowering agent: a prospective cohort study by Changchang Fang, Nanqin Peng, Jiang Cheng, Xiyu Zhang, Wenli Gu, Zicheng Zhu, Xiaoping Yin, Zhiwei Yan, Jing Zhang, Peng Yu, Xiao Liu

“…This study aimed to evaluate whether the association between the TyG index and CVD mortality is influenced by the use of antidiabetic and hypolipidemic agents, given their potential modifying effects on the TyG index. …”
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Early weight gain after stopping smoking: a predictor of overall large weight gain? A single-site retrospective cohort study by Alexandra Pankova, Eva Kralikova, Kamila Zvolska, Lenka Stepankova, Milan Blaha, Petra Ovesna, Paul Aveyard

“…Interventions aimed at all quitters to prevent weight gain on cessation have proven unpopular but targeting people who have gained excess weight immediately after quitting may improve uptake and cost-effectiveness. We examined whether early large postcessation weight gain predicts overall large weight gain.Design Retrospective cohort study.Setting Primary care setting—smoking cessation centre in Prague, Czech Republic.Participants Out of 3537 patients treated between 2005 and 2013, 1050 were continuous abstainers (verified by carbon monoxide measurement) at 1-year follow-up and formed the cohort of the current report. 48.7% were women (n=511) with the mean age of 46 (±14.4) years.Methods In this retrospective cohort study, all patients underwent usual tobacco dependence treatment using evidence-based methods. …”
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Association of liver biopsy pathology on outcome of patients undergoing heart transplantation by Lauren S. Eichenwald, MD, Raffi Karagozian, MD, Adam J. Eichenwald, PhD, John Morrissey, MD MBA, Saurav Kini, MD, Ariella Stein, MSCIS-HI, Amanda R. Vest, MBBS MPH

“…Future research should evaluate whether pre-transplant liver biopsy is necessary for all HT candidates or if clinical assessments can adequately stratify risk. …”
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Does binge drinking between the age of 18 and 25 years predict alcohol dependence in adulthood? A retrospective case–control study in France by Marie-Pierre Tavolacci, Joel Ladner, Pierre Déchelotte, Quentin Berthon, Damiano Cerasuolo, Alexandre Baguet

“…Objective A retrospective case–control study was conducted to evaluate whether frequent binge drinking between the age of 18 and 25 years was a risk factor for alcohol dependence in adulthood.Setting The Department of Addictive Medicine and the Clinical Investigation Center of a university hospital in France.Participants Cases were alcohol-dependent patients between 25 and 45 years and diagnosed by a psychiatrist. …”
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Optimasi Pertanian Padi: Peramalan Curah Hujan Berbasis Arima Untuk Penentuan Waktu Tanam Yang Tepat by Sofi Defiyanti, Betha Nurina Sari, Tesa Nur Padilah

“…This prediction aligns with the weather forecast from BMKG for the start of the rainy season in 2023/2024 in West Java. …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…Therefore, it is crucial to investigate the prevalence of cardiovascular sequelae in COVID-19 patients and to determine whether COVID-19 infection acts as an independent risk factor for these outcomes. …”
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