Artesunate, EDTA, and colistin work synergistically against MCR-negative and -positive colistin-resistant Salmonella by Yajun Zhai, Peiyi Liu, Xueqin Hu, Changjian Fan, Xiaodie Cui, Qibiao He, Dandan He, Xiaoyuan Ma, Gongzheng Hu

“…In this article, we found that AS and EDTA could strikingly enhance the antibacterial effects of COL against mcr-1- and mcr-1+ Salmonella strains either in vitro or in vivo, when used in triple combination. …”
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No Difference in Two-Dimensional Kinematic Assessment of a 45-Degree Sidestep Cut Compared to Qualitative Assessment by Lauren Butler, Charles Wyatt, Alexa Martinez, Ashley Erdman, Eryn Milian, Dai Sugimoto, Alex Loewen, Jeffrey Fernandez, Kristin Hayden, Amie DeVerna, Kirsten Tulchin-Francis, Sophia Ulman

“…No significant differences were observed between the quantitative and qualitative criteria for either inter- or intra-rater reliability (Z~obs(intra)~= -0.38, *p*=0.352 and Z~obs(inter)~= -0.30, *p*=0.382)…”
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Honoring the Afro-Colombian musical culture with the naming of Epipedobates currulao sp. nov. (Anura, Dendrobatidae), a frog from the Pacific rainforests by Mileidy Betancourth-Cundar, Juan Camilo Ríos-Orjuela, Andrew J. Crawford, David C. Cannatella, Rebecca D. Tarvin

“…These species can be distinguished by the presence of a bright yellow blotch on the dorsal anterior region of the thigh and on the upper arm of E. currulao sp. nov., blotches that are either more white than yellow or absent in E. boulengeri. …”
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Do wolframin, P-glycoprotein, and GRP78/BiP cooperate to alter the response of L1210 cells to endoplasmic reticulum stress or drug sensitivity? by Simona Kurekova, Lucia Pavlikova, Mario Seres, Viera Bohacova, Jana Spaldova, Albert Breier, Zdena Sulova

“…We induced ERS in cells either by blocking N-glycosylation in the ER with tunicamycin or by blocking ER Ca2+-ATPase activity with thapsigargin, as known ER stressors. …”
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Improving drug repositioning with negative data labeling using large language models by Milan Picard, Mickael Leclercq, Antoine Bodein, Marie Pier Scott-Boyer, Olivier Perin, Arnaud Droit

“…Positive-Unlabeled (PU) learning has been used to overcome this issue by either randomly sampling unlabeled drugs or identifying probable negatives but still suffers from misclassification or oversimplified decision boundaries. …”
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Establishing Normal Variances and Expectations for Quadriceps Limb Symmetry Index Benchmarks Based on Time from Surgery After Anterior Cruciate Ligament Reconstruction. by Sean Hazzard, Saoirse Connolly, Ashley Wiater, Isabella Sprague, Emily Doolan-Roy, Rachel Lampros, Peter D Asnis

“… # Results A total of 164 patients were evaluated. Patients either received bone-tendon-bone (BTB) autograft (n=118) or BTB allograft (n=46) for their ACL graft. …”
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A model-based spectral directional approach reveals the long-term impact of COVID-19 on cardiorespiratory control and baroreflex by Beatrice Cairo, Francesca Gelpi, Vlasta Bari, Martina Anguissola, Pavandeep Singh, Beatrice De Maria, Marco Ranucci, Alberto Porta

“…Regardless of the experimental condition, spectral causality markers did not vary across groups either. Conclusions CK2 markers, in association with an orthostatic challenge, were able to characterize the impairment of cardiorespiratory control and baroreflex in COVID-19 patients long after acute infection resolution and could be exploited to monitor the evolution of the COVID-19 patients after hospital discharge.…”
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Luminescence of bound excitons created near sodium impurity ions in KCl:Na single crystals by K. Shunkeyev, А. Kenzhebayeva, A. Krasnikov, V. Nagirnyi, Sh Sagimbayeva, D. Sergeyev, А. Tilep, Zh Ubaev, A. Lushchik

“…The study is focused on luminescence features of bound excitons (exciton-like formations, ELFs) in KCl:Na single crystals created in the field of sodium impurity ions either directly at photoexcitation or via the recombination of electron-hole pairs. …”
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Self-reported health complaints and healthcare-seeking behaviour among adult people in rural Bangladesh: results from a cross-sectional study by Ashraful Kabir, Baki Billah, Md Nazmul Karim

“…These factors are crucial for understanding health challenges and designing effective healthcare services in rural areas.Design A cross-sectional survey was conducted from May to October 2021.Setting Four randomly selected administrative districts/regions of Bangladesh.Participants A total of 1645 rural participants aged 18 years and older.Outcome measures The study assessed the prevalence of self-reported health complaints and healthcare-seeking behaviours.Results Among the participants, 66% (1084 out of 1645) reported experiencing health complaints, with 80% seeking care and 20% either not seeking care or opting for self-care. Multivariable analysis revealed that participants with formal occupations (adjusted OR (aOR) = 0.609; 95% CI 0.396 to 0.938; p=0.025), those from the second (aOR=1.742; 95% CI 1.014 to 2.991; p=0.044) and fifth quintiles (aOR=1.210; 95% CI 0.726 to 2.019; p=0.465), with non-communicable disease (NCD) related complaints (aOR=5.299; 95% CI 3.673 to 7.643; p <0.001), and those living more than 5 km from healthcare facilities (aOR=1.725; 95% CI 1.040 to 2.861; p=0.034), were more likely to seek healthcare. …”
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Improved growth performance, food efficiency, and lysine availability in growing rats fed with lysine-biofortified rice by Qing-Qing Yang, Pui Kit Suen, Chang-Quan Zhang, Wan Sheung Mak, Ming-Hong Gu, Qiao-Quan Liu, Samuel Sai-Ming Sun

“…In this study, a 70-day rat feeding study was conducted to assess the nutritional value of two transgenic lines as compared with either their wild type (WT) or the WT rice supplemented with different concentrations of L-lysine. …”
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A comparative study of traditional high-fidelity (manikin-based) simulation and virtual high-fidelity simulations concerning their effectiveness and perception by Izabela Sałacińska, Patrycja Trojnar, Krisztina Éles Gebriné, Viktória Törő, Viktória Törő, Attila Sárváry, Paweł Więch

“…After completing the scenario, students filled in the following questionnaires: the Simulation Design Scale (SDS), the Educational Practices Questionnaire (EPQ), the Student Satisfaction and Self-Confidence in Learning Scale (SSCL) and a customized survey questionnaire.ResultsThe study found no significant difference in the effectiveness of HFS between students exposed to either type of simulation. Detailed analysis within specific categories – problem-solving, teamwork, and active learning – also showed no significant differences between virtual and traditional HFS. …”
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Evaluating GRU Algorithm and Double Moving Average for Predicting USDT Prices: A Case Study 2017-2024 by RAHMAT, Munirul ula, Zara Yunizar

“…This study evaluates the effectiveness of Gated Recurrent Units (GRU) and Double Moving Average (DMA) in predicting USDT (Tether Coin) prices using historical data from 2017 to 2024, sourced from Investing.com. …”
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The Impact of the 2020 Medicaid Expansion in a Community Clinic Serving the Marshallese Population in a Rural State by Robert Brand, Samantha Robinson, Mohammod Mahmudur Rahman, Alshaimaa Hazaa, Sheena CarlLee, Hanna Jensen

“…Methods Through retrospective review of patients who utilized the community clinic either before (05/2020 to 02/2021) or after (05/2021 to 02/2022) the Medicaid expansion, this study sought to compare patients’ insurance information, number of total patients visiting the clinic, number of total patient visits, referrals per patient, and completed referrals per patient were compared between time periods.   …”
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Behavioural Response To Self-Medication Practice Before and During Covid-19 Pandemic in Western Uganda by Samuel Sunday, Dare, Ejike, Daniel Eze, Isaac, Echoru, Ibe Michael, Usman, Fred, Ssempijja, Edmund Eriya, Bukenya, Robinson, Ssebuufu

“…Those that are aware of self-medication, have heard about it either through different avenues. Respondents who practiced self-medication before the COVID-19 pandemic were 239 (88%); those who practiced self-medication during the COVID-19 pandemic were 156 (57%); those that did not were 115 (43%). …”
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Design and Fabrication of a Motorized Honey Extractor. by Hasahya, Caxton Joel

“…The operation of the machine involves loading honeycomb frames into the frame holder either in radial, tangential,l, or both orientations. …”
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Management Style and Employee Performance in Selected Primary Schools in Kajara County, Ntungamo District by Denis, Kamusiime Banshobeize

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Employee Motivation and Job Performance in the Public Service of Uganda: The Case of the Office of the Director of Public Prosecutions by Batson, Baguma

“…The results showed that there was a strong and positive relationship between motivation and employee performance in ODPP; that 90% of those who mentioned monetary incentives either strongly agreed (65.6%) that this affects their performance which indicated that motivation improves performance and, that despite the low monetary incentives 20.6%, promotion at work places 40.3 %, continued job training at 58.5% and good relationship with supervisors 82% was one of the ways in which employees were motivated at the ODPP. …”
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Transcriptome analysis and cytochrome P450 monooxygenase reveal the molecular mechanism of Bisphenol A degradation by Pseudomonas putida strain YC-AE1 by Adel, Eltoukhy, Yang, Jia, Imane, Lamraoui, M. A., Abo‑Kadoum, Omar, Mohammad Atta, Ruth, Nahurira, Junhuan, Wang, Yanchun, Yan

“…Furthermore, Transformation of E. coli with pET‑32a‑bisdAB empowers it to degrade 66 mg l−1 of BPA after 24 h. Alto‑ gether, the results showed the role of CYP450 in biodegradation of BPA by YC‑AE1. …”
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Assembly of oleosin during efficient extraction: Altering the sequence of defatting solvents by Yu Li, Yuqian Qiao, Yuxuan Zhu, Wangyang Shen, Weiping Jin, Dengfeng Peng, Qingrong Huang

“…High purity oleosin (86 %) was obtained by treatment first with a Floch solution and then with cold acetone and petroleum ether after twice washing OBs with urea. The 3D spatial structure of oleosin was predicted using AlphaFold 2, revealing that the secondary structure of oleosin was dominated by α-helices (>60 %). …”
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OPTIMAL CONDITIONS FOR EXTRACTION PHENOLIC COMPOUNDS AND FLAVONOIDS FROM MILLET BRAN AND STUDYING SOME OF THEIR BIOLOGICAL ACTIVITY by Mariem M. A.AL-Abas, Jassem. M. Nasser

“… The aim of this research is to determine the optimal conditions for extracting phenols and flavonoids from the bran of Iraqi proso millet and Ukrainian foxtail millet, whole and defatted, and  studying some of their biological characteristics. Petroleum ether, methyl alcohol (60% and 80%), distilled water, and ethyl alcohol at concentrations of 60, 80, 90, and 99% were used as extraction solutions. …”
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