Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis by Wenli Xu, Lu Li, Hong Kang, Meixian Wang, Yanqun Liu, Guicun Wang, Ping Yu, Juan Liang, Zhen Liu

“…This study is aims to investigate whether analyzing the microbiota and metabolic profiles of amniotic fluid collected from pregnant women whose fetuses with or without non-syndromic congenital heart defects (CHDs), during the second and third trimester of pregnancy, could offer valuable insights into CHDs. …”
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Metabolites and lipid species mediate the associations of adiposity in childhood and early adulthood with mammographic breast density in premenopausal women by Kayla R. Getz, Myung Sik Jeon, Lili Liu, Lei Liu, Haixiang Zhang, Chongliang Luo, Jingqin Luo, Adetunji T. Toriola

“…We performed high dimensional mediation analysis using the HIMA R package, adjusted for confounders, to determine whether lipid species and metabolites mediate the associations of BMI at 10 and 18 with MBD. …”
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Analisa Sentimen Financial Technology Peer To Peer Lending Pada Aplikasi Koinworks by Rousyati Rousyati, Windu Gata, Dany Pratmanto, Nia Kusuma Wardhani

“…Second, there are risks associated with data security (cyber risk), governance, and customer privacy and also because of system vulnerabilities and data abuse, whether intentionally or unintentionally. Reviews contained in the Google Play comments column can be used as a data source that can be shared with data mining. …”
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Carbon sequestration in different urban vegetation types in Southern Finland by L. Thölix, L. Backman, M. Havu, M. Havu, E. Karvinen, J. Soininen, J. Trémeau, O. Nevalainen, J. Ahongshangbam, L. Järvi, L. Järvi, L. Kulmala

“…Our analysis revealed that these models effectively simulated seasonal and annual variations, as well as the impacts of weather events on carbon fluxes and related factors. …”
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Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis by Lingling Zhao, Cheng Xu, Jiewen Deng, Yang Ni

“…This meta-analysis aims to assess whether the integration of HAIC with lenvatinib and PD-1 inhibitors (referred to as the HAIC-L-P group) leads to better treatment effectiveness and security compared to lenvatinib and PD-1 inhibitors alone (L-P group) in uHCC.MethodsAn exhaustive search of the literature was conducted, including PubMed, the Cochrane Library, Embase, ClinicalTrials.gov, and Web of Science, from the start of each database until September 2024, to ensure a thorough and up-to-date compilation of relevant studies. …”
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Blowin’ in the Nonisothermal Wind: Core-powered Mass Loss with Hydrodynamic Radiative Transfer by William Misener, Matthäus Schulik, Hilke E. Schlichting, James E. Owen

“…In some cases, the choice of opacities determines whether or not a planet can retain a significant primordial hydrogen atmosphere. …”
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Microbial dynamics of acute pancreatitis: integrating culture, sequencing, and bile impact on bacterial populations and gaseous metabolites by Agnieszka Chmielarczyk, Edyta Golińska, Anna Tomusiak-Plebanek, Natalia Żeber-Lubecka, Natalia Żeber-Lubecka, Maria Kulecka, Maria Kulecka, Antoni Szczepanik, Katarzyna Jedlińska, Krzysztof Mech, Konrad Szaciłowski, Agata Kuziak, Agata Pietrzyk, Magdalena Strus

“…The therapeutic intervention necessitated Hartmann's procedure, culminating in colostomy creation.AimsEmploying a thorough microbiological analysis we attempted to demonstrate whether the microflora isolated from the peripancreatic fluid exhibited a stronger correlation with the contents of the stoma or with the rectal swab. …”
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Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation by Sören J. Backhaus, Alexander Schulz, Torben Lange, Simon F. Rösel, Lennart S. Schmidt-Schweda, Shelby Kutty, Johannes T. Kowallick, Julia Treiber, Andreas Rolf, Samuel Sossalla, Gerd Hasenuß, Andreas Schuster

“…RV long axis strain at rest and during exercise-stress decreased in HFpEF (p = 0.007 for both) but neither in NCD nor HFpEF with IASD. In contrast, in NCD, an improvement in LA LAS during exercise-stress (p = 0.028) was noted. …”
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Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4 by Rongyu Shi, Ning Zhang, Han Li, Hu Zhong, Chengcheng Zhong, Wei Du, Xi Yang

“…Here, this study focused on investigating whether CAFs affected GEM resistance in PC by secreting COL17A1 and its associated mechanisms. …”
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Predicting the reduction in heatstroke and heart disease-related mortality under urban modification scenarios using machine learning by Yukitaka Ohashi, Ko Nakajima, Yuya Takane, Yukihiro Kikegawa, Tomohiko Ihara, Kazutaka Oka

“…These methods have been used separately to assess the future urban health. The Weather Research and Forecasting–Canopy-Building Energy Model (WRF–CMBEM) was used to simulate spatiotemporal urban meteorological conditions, and ML was applied to predict daily heat-related deaths in the 23 wards of Tokyo during the extremely hot summer of 2018. …”
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Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study by Yong-Ping Lu, Bin Xia, Xiao-Hua Wang, Qiang-Sheng He, Chang-Bo Qu, Ying-Ying Xie, Tian-Jiao Cui, Si-Qing Wu, Jin-Yu Zhao, Zhi-Hua Zheng, Ting Zhu, Jin-Qiu Yuan, Chun Tang

“…Further clinical trials are needed to confirm whether adherence to such diets can lower the risk of CKD.…”
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Diagnostic performance of digital breast tomosynthesis (DBT) versus digital mammography (DM) in a population clinically referred for breast imaging – a retrospective cohort study by Naomi Noguchi, Farzaneh Boroumand, Katy Bell, Margaret Pooley, Aileen Zeng, Lauren Arnold, Armando Teixeira-Pinto, Nehmat Houssami

“…Within this subgroup, AUC-ROC for DBT was 0.90 (CI 0.84–0.95) and for DM it was 0.85 (CI 0.79–0.92), sensitivity was 78.2 % (CI 65.0–88.2 %) for DBT and 64.8 % (CI 50.6–77.3 %) for DM, and ultrasound was accurate whether it was used with DBT (AUC-ROC 0.95 (CI 0.91 – 0.99)) or DM (AUC-ROC 0.95 (CI 0.90 – 0.99)) Conclusion: In clinically referred patients, diagnostic accuracy and diagnostic yield were similar between DBT and DM. …”
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Evidence Graph Analysis of Postoperative Pain Sensitization Induced by Perioperative Sleep Deprivation by XUE Jianjun, WANG Caihong, GUO Lingling, LI Xiuxia, ZHANG Jie, XU Ziqing, HOU Huaijing, YANG Kehu

“…Only 2 studies suggested that sleep disorders were not significantly associated with postoperative pain sensitization, and ten studies were uncertain whether sleep deprivation could induce postoperative pain sensitization.ConclusionsOverall evidence shows that sleep deprivation can induce postoperative pain sensitization, but the evaluation dimensions are limited and the methodological quality of the included literature needs to be improved. …”
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Adipocyte-specific Steap4 deficiency reduced thermogenesis and energy expenditure in mice by Han Wang, Lizi Zhang, Xing Chen, Lingzi Hong, Junjie Zhao, Wen Qian, Lam Khue Pham, Belinda Willard, Xiaoxia Li, Katarzyna Bulek, Xiao Li

“…Dysregulated adipose and mitochondrial metabolism contributes to obesity, highlighting the need to understand their interplay. Whether and how Steap4 influences mitochondrial function, adipocytes, and energy expenditure remain unclear. …”
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Environmental pollution evaluation and spatiotemporal distribution of different forms of phosphorus in a phosphate mining area in Western Hubei, China by Lei Kou, Junwei Zhang, Liyue Huang, Guanyu Chen, Shupeng Jiang, Ding Han, Dayuan Jiang

“…Taking the typical phosphate mining area in Western Hubei as the research object, groundwater, surface water, soil and sediment in phosphate mining area were investigated and evaluated comprehensively to clarify the temporal and spatial distribution characteristics of different forms of phosphorus in phosphate mining area and reveal the migration and transformation of phosphorus. Results showed that whether in the dry season or the wet season, total phosphorus levels in groundwater (dry season from November to December 2021, 0.42 mg/L; wet season from August to September 2022, 0.24 mg/L) exceeded the standard index. …”
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Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults by Yuankang Zhu, Zhenlin Yang, Yuhao Chen, Lingzi Qian, Changning Hao, Liangshi Hao, Boshen Yang, Junli Duan

“…Recent data from animal experiments have proved its potential cardiovascular toxicity. However, whether glyphosate exposure influences human cardiovascular health at the population levels remains unknown. …”
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Preoxygenation in difficult airway management: high-flow oxygenation by nasal cannula versus face mask (the PREOPTIDAM study). Protocol for a single-centre randomised study by Samir Jaber, Karim Asehnoune, Fanny Feuillet, Mickael Vourc’h, Donatien Huard, Gabrielle Baud, Arthur Guichoux, Marielle Surbled, Melanie Tissot, Anne Chiffoleau, Christophe Guitton

“…The primary objective is to determine whether HFNC is more efficient than standard oxygenation techniques to prevent desaturation ≤94% or face mask ventilation during DI. …”
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Scoping review of climate drivers on maternal health: current evidence and clinical implicationsAJOG Global Reports at a Glance by Claire Masters, MHP, Chuhan Wu, MS, Dara Gleeson, MPH, Michaela Serafica, RN, MSN, Jordan L. Thomas, PhD, Jeannette R. Ickovics, PhD

“…Continuing education for clinicians, and clinician-patient communications should be expanded to address risks of climate change and extreme weather exposure, especially risks of extreme heat in late-pregnancy. …”
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Political economy analysis of health financing reforms in times of crisis: findings from three case studies in south-east Asia by Sophie Witter, Maria Paola Bertone, Sushil Baral, Ghanshyam Gautam, Saugat K. C. Pratap, Aungsumalee Pholpark, Nurmala Selly Saputri, Arif Budi Darmawan, Nina Toyamah, Rizki Fillaili, Valeria de Oliveira Cruz, Susan Sparkes

“…The objective is to understand whether and how crises can be utilised to progress UHC and to analyse the strategies used by reformers to benefit from potential windows of opportunity. …”
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Penyeimbangan Kelas SMOTE dan Seleksi Fitur Ensemble Filter pada Support Vector Machine untuk Klasifikasi Penyakit Liver by Muhammad Amir Nugraha, Muhammad Itqan Mazdadi, Andi Farmadi, Muliadi, Triando Hamonangan Saragih

“…Classification of liver disease in patients needs to be done well because the results can help in the initial diagnosis of whether a patient has liver disease. Based on previous research, the Support Vector Machine (SVM) method best classifies liver disease patients. …”
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