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6521
Data-Sharing Statements Requested from Clinical Trials by Public, Environmental, and Occupational Health Journals: Cross-Sectional Study
Published 2025-02-01“… BackgroundData sharing plays a crucial role in health informatics, contributing to improving health information systems, enhancing operational efficiency, informing policy and decision-making, and advancing public health surveillance including disease tracking. …”
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6522
Experimental implementation of a non-ideal three-waveplate array as a polarization disturbance corrector
Published 2025-03-01“…The proposed theoretical framework, based on the mathematical treatment of polarization and its relation with the mathematical structure of the SU(2) Lie group, reveals the fundamental role of the transformations performed by a three-waveplate array in correcting polarization disturbances while analytical expression are deduced. …”
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6523
High-resolution Cryo-EM Structure Determination of a-Synuclein—A Prototypical Amyloid Fibril
Published 2025-02-01“…The physiological role of a-synuclein (a-syn), an intrinsically disordered presynaptic neuronal protein, is believed to impact the release of neurotransmitters through interactions with the SNARE complex. …”
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6524
Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells
Published 2025-02-01“…Integrins, as valuable prognostic markers in cancer, have importance in exosome-cell interaction. However, the role of exosome integrins in chemoresistant colorectal cancer remained unclear. …”
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6525
Taung and beyond: The mining history, geology and taphonomy of Australopithecus in South Africa
Published 2025-02-01“…We mark this moment in our field by critically reflecting on the role of extractive practices, especially centred around past mining of the Caves and the exclusion of many members of research teams. …”
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6526
Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients with chronic coronary artery disease (CAD) - current state of knowledge and perspective...
Published 2025-02-01“…Despite its established role, the optimal duration and specific composition of DAPT still remain under investigation. …”
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6527
Fossil and Non-fossil Fuel Sources of Organic and Elemental Carbonaceous Aerosol in Beijing, Shanghai, and Guangzhou: Seasonal Carbon Source Variation
Published 2020-06-01“…During spring and summer, FF played a greater role than NF in Beijing (~55%) and Guangzhou (~63%); additionally, based on our limited number of samples, it contributed 71% in Shanghai during the latter season, with a significant portion due to fuel combustion (i.e., industrial, vehicular, fishing-boat, and large-vessel emissions).…”
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6528
Elimination of olfactory sensory neurons by zinc sulfate inoculation prevents SARS-CoV-2 infection of the brain in K18-hACE2 transgenic mice
Published 2024-11-01“…Using a K18-human angiotensin converting-enzyme 2 (hACE2) transgenic mouse model with impaired olfactory sensory neurons (OSNs) induced by zinc sulfate, we examined the role of the olfactory nerve in the brain invasion by SARS-CoV-2. …”
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6529
Compressive mechanical properties of Zr-based bulk metallic glass composites reinforced with entangled porous tungsten wire
Published 2025-03-01“…The direction or distribution of tungsten wire plays a great role in deformation and fracture behaviors of the bulk metallic glass composites. …”
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6530
TMEM97 governs partial epithelial-mesenchymal transition of retinal pigment epithelial cells via the CTNND2-ADAM10 axis
Published 2025-03-01“…Epithelial-mesenchymal transition (EMT) is associated with retinal pigment epithelium (RPE) dysfunction in degenerative retinal diseases. However, the role of partial EMT (pEMT), a hybrid state exhibiting both epithelial and mesenchymal markers, remains poorly understood in this context. …”
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6531
Pharmacological regression of atherosclerotic plaque in patients with type 2 diabetes
Published 2025-03-01“…Vulnerable plaques are characterized by a softer atheromatous core and a thinner fibrous cap, with inflammation and hypercholesterolemia playing a crucial role in the atherothrombotic process. Based on animal studies that extend back to the 1920s, regression of atherosclerotic plaques in humans has just started to be considered and pursued. …”
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6532
Anti-inflammatory effects of Andrographis paniculata (Fah Talai Jone) via TNFα-JNK pathway and bioactive compound identification
Published 2025-02-01“…This study investigates its bioactive compounds and their role in alleviating inflammation through the TNF-α-JNK pathway. …”
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6533
Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Afric...
Published 2025-02-01“…African buffaloes (Syncerus caffer) are wildlife maintenance hosts of Mycobacterium bovis (M. bovis), the causative agent of animal tuberculosis (aTB) in multiple ecosystems across South Africa. In addition to their role as keystone species, these animals are vital to South Africa’s economy as a highly valuable species. …”
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6534
Towards equitable carbon responsibility: Integrating trade-related emissions and carbon sinks in urban decarbonization
Published 2025-03-01“…Cities play a pivotal role in global decarbonization, acting as a critical driver of carbon emissions. …”
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6535
Perceived barriers to physical activity and their predictors among adults in the Central Region in Saudi Arabia: Gender differences and cultural aspects.
Published 2025-01-01“…Multivariate analysis revealed that females were 14% more likely than males to report external barriers to physical activity (OR = 1.14; 95% CI: 1.04-1.25; p = 0.018), suggesting gender plays a role in perceived external obstacles. Additionally, older age, higher body mass index, higher education level, marriage, certain employment statuses, and chronic diseases were significantly associated with increased reported internal and external barriers. …”
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6536
Synthesis of acrylonitrile functionalized hydroxymethylfurfural derivatives with Mg(OH)$_{{2}}$ under solvent-free conditions
Published 2023-08-01“…We found that water plays an essential role in obtaining high yields. By using this simple and inexpensive method, we were able to achieve yields near 90% in short reaction times ($<$30 min).…”
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6537
Regular exercise in adolescents with ACE gene polymorphism helps preventing cardiovascular risk factors
Published 2025-02-01“…These include the renin-angiotensin-aldosterone system (RAAS), which plays, along with other environmental factors, a fundamental role in the pathogenesis of essential arterial hypertension in both adults and adolescents. …”
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6538
Machine learning reveals sex differences in distinguishing between conduct-disordered and neurotypical youth based on emotion processing dysfunction
Published 2025-02-01“…Abstract Background Theoretical models of conduct disorder (CD) highlight that deficits in emotion recognition, learning, and regulation play a pivotal role in CD etiology. With CD being more prevalent in boys than girls, various theories aim to explain this sex difference. …”
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6539
Unveiling Hidden Aspects of Intermediary Organizations in Innovation: A Systematic Review through the Lens of Industry Taxonomy
Published 2024-04-01“…The unsteady interactions between the actors make the role of intermediaries important. Intermediary organizations in the innovation system try to assume functions based on the deficiencies in the interactions. …”
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6540
The kinetics of maternal and self-developed Streptococcus suis-specific antibodies
Published 2025-02-01“…The immune gap caused by decreased maternal-derived antibodies (MDA) and insufficient levels or functionality of acquired antibodies in weaned pigs could play a role in the increased susceptibility to S. suis infections. …”
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