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6501
Bergapten alleviates senescence of chondrocytes in osteoarthritis
Published 2025-02-01“…Objective To investigate the role and mechanism of bergapten in treating osteoarthritis (OA) based on network pharmacology, molecular docking and in vitro experiments. …”
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6502
Characteristics and Influencing Factors of Soil CH4 and N2O Fluxes in Typical Broad-leaved Forests in the Yangtze River Delta Region, China
Published 2024-12-01“…[Conclusion] The research results indicate that broad-leaved forests have an important role in forest carbon sinks, and the management of soil litter in broad-leaved forest is crucial for balancing CH4 absorption and N2O emissions, as well as mitigating climate warming.…”
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6503
Ewolucja „Lamusa” – od lokalnego periodyku o charakterze literacko-artystycznym po quasi-naukowe czasopismo specjalistyczne o zasięgu ogólnopolskim
Published 2024-12-01“…Celami artykułu są analiza korpusu oraz zarysowanie tła lokalnego czasopiśmiennictwa, aby unaocznić rolę „Lamusa” w Gorzowie Wielkopolskim. W czasie, gdy był publikowany, stanowił jeden z najbardziej opiniotwórczych regionalnych magazynów literackich. …”
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6504
Vitamin B12, folate, and homocysteine levels in children and adolescents with obesity: a systematic review and meta-analysis
Published 2025-02-01“…However, no significant differences were found for vitamin B12 and folate levels. Hcy may play a role in the development of obesity in this population.…”
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6505
Characterization of subcutaneous and visceral de-differentiated fat cells
Published 2025-03-01“…This knowledge may shed light on their role in life style change-induced weight loss and regain.…”
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6506
The ground beneath our feet: A critical reflection on 135 years of landscape evolution models for southern Africa
Published 2025-02-01“… In his 1925 paper describing the Taung Child fossil, Dart makes various assertions about the landscape around Taung, inferring past climate dynamics, and the role these factors play in the evolution of our early prehuman relatives. …”
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6507
Research trends in glioma chemoradiotherapy resistance: a bibliometric analysis (2003–2023)
Published 2025-02-01“…Recent research emphasizes the role of the tumor microenvironment (TME) and immune modulation in glioma progression and resistance. …”
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6508
Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities
Published 2025-01-01“…Saline-alkaline aquaculture plays a crucial role in the ecological restoration of saline soils, yet high water salinity can significantly restrict the growth of cultured organisms. …”
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6509
Yiqi Juanshen decoction alleviates renal interstitial fibrosis by targeting the LOXL2/PI3K/AKT pathway to suppress EMT and inflammation
Published 2025-02-01“…This modulation of the LOXL2/PI3K/AKT pathway contributes to the inhibition of both EMT and inflammation, highlighting a critical role in the therapeutic intervention against RIF. …”
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6510
Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease
Published 2025-02-01“…Early infection of both tissue and immune cells, such as macrophages, leading to pyroptosis-mediated inflammasome production in an organ system critical for systemic oxygenation likely plays a central role in the morbidity wrought by SARS-CoV-2. Delayed transcription of Type I and Type III interferons by SARS-CoV-2 may lead to early disinhibition of viral replication. …”
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6511
The serum hepcidin and the hepcidin/ferritin ratio in NAFLD: a systematic review and meta-analysis
Published 2025-02-01“…Further investigations are needed to fully elucidate the role of these variables in iron metabolism and their potential impact on the diagnosis, prevention, and management of NAFLD.…”
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6512
MiR-128-3p mediates MRP2 internalization in estrogen-induced cholestasis through targeting PDZK1
Published 2025-02-01“…Emerging evidence indicates that PDZ domain containing 1 (PDZK1) regulates localization of MRP2; however, PDZK1’s role and regulatory machinery in MRP2-mediated estrogen-induced cholestasis (EIC) remain unclear. …”
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6513
mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction
Published 2025-01-01“…We investigated the novel role of mitochondrial STAT3 (mitoSTAT3) in Th17 cells and fibroblast-like synoviocytes (FLSs) and analyzed the correlation of mitoSTAT3 with RA. …”
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6514
Virtual Reality Simulation for Undergraduate Nursing Students for Care of Patients With Infectious Diseases: Mixed Methods Study
Published 2025-02-01“…The positive impact on student motivation and attitudes indicates a potentially transformative approach to nursing education, particularly in the post–COVID-19 era, where digital and remote learning tools play an increasingly vital role.…”
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6515
Phthalate exposure induces microRNA-5010/Nrf2-EGR1/GDF15 signaling expression in prostate cancer
Published 2025-01-01“…Phthalate exposure is linked to prostate enlargement through sex hormonal changes and oxidative stress. However, its role and action mechanism in prostate cancer remain unclear. …”
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6516
Spatial and temporal variation of Antarctic microbial interactions: a study around the west Antarctic Peninsula
Published 2025-02-01“…Overall, in terms of biotic drivers, causal-effect modelling suggests that bacteria were stronger drivers of ecosystem dynamics at Palmer, while microbial eukaryotes played a stronger role at Rothera. The parasitic taxa Syndiniales persevered at both sites across the seasons, with Palmer and Rothera harbouring different key groups. …”
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6517
Mental health literacy and associated factors among traditional healers of Jimma town, southwest, Ethiopia 2020: a community based, cross-sectional study
Published 2024-05-01“…In Ethiopia, different studies were done focusing on the role of traditional medicine and perception of the community toward traditional medicine. …”
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6518
Investigating the formation and evolution of plant diversity patterns in the Qiangtang Plateau based on phylofloristics approach
Published 2025-04-01“…These findings underscore the pivotal role of the uplift of the Qiangtang Plateau and the climatic shifts during the Quaternary Ice Age as primary drivers shaping the region's contemporary distribution patterns of alpine plants.…”
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6519
Associations between hypovitaminosis D, adiposity indices and insulin resistance in adolescents: mediation analyses from NHANES 2011–2018
Published 2025-02-01“…Furthermore, we applied mediation analysis to precisely assess the mediating role of adiposity indices in the relationship between hypovitaminosis D and IR. …”
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6520
Peran Interaktivitas dalam Penggunaan E-learning: Perluasan Model UTAUT
Published 2023-02-01“… Perubahan proses belajar mengajar menjadi daring dilaksanakan oleh STMIK Mikroskil untuk mematuhi kebijakan yang dibuat Menteri Pendidikan dan Kebudayaan dalam masa darurat penyebaran covid-19 di Indonesia. …”
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