Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis by Tan Y, Qian B, Ma Q, Xiang K, Wang S

“…These key genes were all enriched in the same pathways, such as GOCC_azurophil_granule, IL-12 signalling and production in macrophages is the pathway with the strongest role for key genes. Six distinct immune cells, including naive CD4 T cells, T cells CD4 memory resting, T cells regulatory (Tregs), Monocytes, Macrophages M2, Neutrophils were identified. …”
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IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury by Liwu Zeng, Yaxin Wang, Yongzhou Huang, Wenchang Yang, Pei Zhou, Yaqi Wan, Kaixiong Tao, Ruidong Li

“…IRG1 and its metabolites play important roles in infection, immune-related diseases and tumor progression by exerting resistance of pathogens, attenuating inflammation and producing antioxidant substances through various pathways and mechanisms. …”
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Phosphorus transitions driven by cyclone biparjoy linked middle east North Africa (MENA) and Indian Thar Desert dust storm pathways in Asia’s largest grassland by Rupak Dey, Seema B. Sharma, Mahesh G. Thakkar, Ranjit Kumar Sarangi, Abhiroop Chowdhury, Aliya Naz

“…Abstract Phosphorus (P) is an important nutrient for terrestrial ecosystems like grassland and plays a critical role in influencing primary productivity and hence ecosystem dynamics. …”
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ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…BackgroundIntegrin Subunit Alpha 4 (ITGA4), a member of the integrin protein family, is involved in the progression of malignant tumors. However, its role across different cancer types is not well understood.MethodsUtilizing multi-omics data, we comprehensively evaluated ITGA4’s expression, clinical relevance, diagnostic and prognostic value, functions, mutations, and methylation status, along with its impact on immunity, mismatch repair (MMR), heterogeneity, stemness, immunotherapy responsiveness, and drug resistance in pan-cancer, with partial validation in gastric cancer (GC) using transcriptomic analysis, single-cell data, western blot (WB), wound-healing assay, flow cytometry and immunohistochemistry (IHC). …”
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FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis by Yu Cheng, Yang Jiao, Wan Wei, Mengjia Kou, Yaodong Cai, Yang Li, Hao Li, Tonghua Liu

“…The protective effects of FBR2 were reversed by Erastin, confirming the central role of ferroptosis in pulmonary fibrosis treatment. …”
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Political economy analysis of health financing reforms in times of crisis: findings from three case studies in south-east Asia by Sophie Witter, Maria Paola Bertone, Sushil Baral, Ghanshyam Gautam, Saugat K. C. Pratap, Aungsumalee Pholpark, Nurmala Selly Saputri, Arif Budi Darmawan, Nina Toyamah, Rizki Fillaili, Valeria de Oliveira Cruz, Susan Sparkes

“…Changing decision rules to block veto points was significant in one case, and all three cases used participation and dialogue strategically to further reforms. …”
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Zmartwychwstanie przez technikę. Problem tożsamości umysłu w koncepcjach rozwoju sztucznej inteligencji. by Olgierd Sroczyński

“…Moreover, while the concept of consciousness that hypothetical artificial intelligence might attain at a human level is frequently discussed, there is a lack of reflection on the role of another element of human cognition, namely identity. …”
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„Uniwerek” – opieka nad dziećmi w wieku do lat trzech. Od inspiracji do realizacji by Anna Godlewska-Zaorska, Bernadetta Olender-Jermacz

“…It has a caring, upbringing and educational role. It is located in the Kortowo campus. In the considerations presented, we used the sociocultural perspective, which showed our way of understanding the nature of the learning process, as well as defined the vision/ role of the child and tutor, educator, teacher and the environment in this space. …”
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Patient-reported outcome measures and value-based medicine in paediatrics: a timely review by Yi Hua Tan, Jia Xuan Siew, Biju Thomas, Kee Chong Ng

“…This review covers the role of PROMs in paediatrics, as well as their role in value-based medicine.…”
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The promise of attending to literary context for contextual biblical hermeneutics in Africa by D.W. Ellington

“…Repercussions can include a limited role of Jesus Christ and a heightened role of material prosperity in some African expressions of Christian faith. …”
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Do digital influencers successfully contribute to reducing the gap between customers and companies? by Isaac Moreira, Paulo Stenzel, João M. Lopes, José Oliveira

“…The purpose of this research is to analyze the role of digital influencers in the construction of relationships between companies and consumers. …”
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Understanding spiritual experience in Christian spirituality by S. P. Pretorius

“…Others acknowledge that certain role-players are present when spiritual experiences occur. …”
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Reassessing standardized tests: Evaluating their effectiveness in school performance measurement by Oyeronke Christiana Paramole, Moses Adeleke Adeoye

“…This research article reassesses the role of standardized tests in educational assessment, focusing on their complexities, historical context, and implications. …”
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Protected areas for environmental sustainability in Nigeria by OI Imasuen, JN Oshodi, TUS Onyeobi

“…Attempt was then made to determine if the country has lost its bearings with regards to the role of cultural heritage and the natural environment. …”
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Identity and community in South African congregations by W. J. Schoeman

“…The two surveys suggest that attenders prefer a private expression of their religion in which the Bible plays an important role. They have a strong bond with the congregation, but the preferred role of the congregation is to provide in the spiritual needs of the attenders. …”
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Is heme biosynthesis influenced the mitochondrial function and cell proliferation in cancer? by Raisa Nauli, Sri Widia A Jusman

“…Protoporphyrin combines with a protein-forming hemoprotein compound that plays an essential role in oxygen-binding and transport as well as in the process of energy production in the mitochondria. …”
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The reception of Apphia in the fourth and fifth centuries C.E. by D. F. Tolmie

“…Lastly it is shown that personal views on women and their role had no mean influence on the perception of Apphia. …”
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Metabolism of bile acids, liver diseases and microbiome by Yu. V. Yevsyutina, V. T. Ivashkin

“…Enterohepatic circulation of BA plays the central role in nutrient absorption and metabolic regulation. …”
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GENERAL EDUCATIONAL ASPECT OF A MINERALOGICAL MUSEUM OF THE NORTH-EASTERN FEDERAL UNIVERSITY, YAKUTSK by O.G. Tretiakova, V.R. Filippov, I.V. Kozlova, V.F. Popov

“…The restoration, preservation and development of the NEFU mineralogical museum requires a conceptual rethinking of its role, expansion of its functional capabilities, awareness and reassessment of its social role for the university, city and region. …”
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Orlando, Florida’s Urban and Community Forests and Their Ecosystem Services by Edem K. Ekpe, Elizabeth Becker, Jessica Lab, Ross Hinkle, Francisco Escobedo

“… Urban forests, or the trees and shrubs on these land uses, play an important role in providing ecosystem services and are often key components in urban planning and management as well as in environmental regulations. …”
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