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13721
Effects of bioactive peptides combined with probiotics on serum uric acid in patients with hyperuricemia
Published 2025-01-01“…Objective: To evaluate the effect of bioactive peptides combined with probiotics on serum uric acid (SUA) in patients with hyperuricemia (HUA), so as to provide the evidence for prevention and treatment of HUA. Methods: The patients with HUA aged 18 to 65 years were selected and randomly divided into an intervention group and a control group. …”
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13722
Technologically-Treated Polyclonal Affinity-Purified Antibodies to the Tumor Necrosis Factor-α, Brain Specific S-100 Protein and Histamine in Treatment of Functional Dyspepsia: Res...
Published 2022-09-01“…The aim of the study was to evaluate the efficacy and safety of Kolofort® (a complex medicine containing technologically processed forms of antibodies to S-100 protein, tumor necrosis factor-α and histamine) in the management of functional dyspepsia (FD) in outpatient clinical practice.Methods: Outpatients (N = 309) at the age of 18–45 in whom FD was diagnosed according to the Rome IV criteria were enrolled in a multicenter, double-blind, placebo-controlled, randomized clinical trial. …”
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13723
Exploring information technology utilization and needs in community pharmacies: a cross-sectional survey in Shanghai, China
Published 2025-02-01“…Integrating information technology (IT) into community pharmacies can improve medication management by providing timely access to patient information, enhancing medication safety, and facilitating communication with healthcare providers.ObjectiveThis study aimed to explore the medication management practices of community pharmacists, the existing IT support available, and their specific requirements for IT-assisted medication management in community pharmacies in Shanghai, China.MethodsAn online self-assessment survey was conducted to evaluate the utilization and needs of IT-based medication management among community pharmacists in Shanghai. …”
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13724
Network Meta-Analysis of Once Weekly Selinexor-Bortezomib-Dexamethasone in Previously Treated Multiple Myeloma
Published 2021-08-01“…**Objectives:** A Bayesian network meta-analysis (NMA) was developed from studies identified from a systematic literature review (SLR) to evaluate the efficacy of once weekly oral selinexor with once weekly bortezomib and low-dose dexamethasone (XVd) relative to other therapies in previously treated MM. **Methods**: Ovid was systematically searched for phase 2-3 randomized clinical trials (RCTs) in MM that assessed progression-free survival (PFS), overall survival (OS) and overall response rates (ORR). …”
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13725
Effect of HBeAg/anti-HBe coexistence on HBeAg seroconversion in treatment-naïve chronic hepatitis B patients with peginterferon-α
Published 2025-02-01“…Design: Retrospective, case–control study of treatment-naïve CHB patients with Peg-IFN-α at a tertiary care center. Methods: Data from HBeAg-positive treatment-naïve CHB patients were retrospectively analyzed. …”
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13726
Urban-rural difference in adverse outcomes of pulmonary tuberculosis in patients with pulmonary tuberculosis-diabetes mellitus comorbidity
Published 2025-01-01“…Objective:To investigate the urban and rural differences in adverse outcomes of pulmonary tuberculosis (PTB) in patients with pulmonary tuberculosis-diabetes mellitus comorbidity (PTB-DM), so as to provide insights into improving the prevention and treatment measures for PTB-DM. Methods:Patients with PTB-DM who were admitted and discharged from 14 designated tuberculosis hospitals in Hangzhou City from 2018 to 2022 were selected. …”
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13727
INTEGRATION OF UKRAINIAN CHILDREN AND YOUTH USING DIGITAL TOOLS IN THE EDUCATIONAL ENVIRONMENT OF SLOVAKIA
Published 2024-06-01“…General scientific and special research methods were used. We summarized the results of the general report of the study "Support for emigrants from Ukraine in education", which was conducted in Slovakia during 2022–2023 by the National Institute of Education and Youth in cooperation with the Ministry of Education, Science, Research and Sports of the Slovak Republic and in cooperation with the United Nations Children's Fund as well as the report "Distance education of students during the COVID-19 pandemic in the context of teacher training". …”
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13728
High-quality DNA extraction for Desmodium gangeticum: A medicinal shrub of Shivalik Himalayas
Published 2025-01-01“…Setting: This study was conducted under controlled laboratory environment at Manav Rachna Centre for Medicinal Plant Pathology, Department of Biotechnology, Manav Rachna International Institute of Research and Studies, Faridabad, India. Methods: Advanced techniques, commercial kits and rigorous modifications in existing DNA extraction buffer conditions and extraction protocols from both fresh and dried leaves are considered to optimise high-quality DNA isolation. …”
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13729
VICTIM OF AN OFFENCE: LEGAL AND ECONOMIC ANALYSIS IN AN INTERJURISDICTIONAL CONTEXT
Published 2024-12-01“…The chosen research methodology is based on the methods of systematic analysis, comparison and interdisciplinary (legal/economic) research. …”
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13730
Mortality Prediction in the Emergency Service Intensive Care Patients with Possible COVID-19: A Retrospective Cross-Sectional Study
Published 2024-11-01“…This study aims to determine the impact COVID-19 on mortality, evaluate the performance of Acute Physiology and Chronic Health Evaluation-2 Scores (APACHE II), Sequential Organ Failure Assessment Scores (SOFA) and Pneumonia Severity Index (PSI) for mortality prediction in the COVID-19 suspected patients. MATERIALS AND METHODS: This study is a retrospective cross-sectional analysis of patients who were admitted to the pandemic intensive care unit with possible COVID-19. 28-day mortality difference between positive and negative groups was defined as the primary outcome. …”
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13731
Efficacy of Kolofort in Combined Functional Gastroenterological Pathology: an Open Study
Published 2020-12-01“…The study aims to evaluate the efficacy and safety of Kolofort administration in patients suffering from irritable bowel syndrome (IBS) and functional dyspepsia (FD), as well as the prevalence of somatic and polymorbid psychomental disorders (distress, depression, anxiety and somatisation) in these patient groups using questionnaires “7×7” and “4DSQ”.Materials and methods. The study included 56 patients with IBS and FD diagnosed according to the Rome IV revision criteria and the Clinical Guidelines of the Russian Gastroenterological Association, the average age was 36.36 ± 6.42 years. …”
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13732
Analysis of expression and transport activity of sugar transporter gene HpSWEET7 from red pitaya
Published 2025-01-01“…[Objective] The red pitaya (Hylocereus polyrhizus) HpSWEET7 gene, belonging to the sugar transporter SWEET (sugars will eventually be exported transporter) family, was cloned and its role in fruit sugar accumulation was investigated, which provided a target gene for improving fruit flavor and quality. [Methods] HpSWEET7 gene was isolated from ‘Zihonglong’, and sequence alignment and phylogenetic relationship were analyzed. …”
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13733
Functional Outcome of Mesenchymal Stem Cells Vs. Hyaluronic Acid in Knee Osteoarthritis Kellgren-Lawrence Grade I-III At 6-and 12-Months Follow-Up: A Meta-Analysis
Published 2023-10-01“…The primary objective of this research is to offer substantiation and recommendations for advancing and utilizing MSC therapy in clinical settings, in contrast to the use of hyaluronic acid (HA) as the standard control group. Methods: This study was a meta-analysis conducted through a search for relevant scientific reports in PubMed, Embase, and Google Scholar, using some keywords such as "mesenchymal stem cell," "hyaluronic acid," and "osteoarthritis." …”
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13734
Polysomnographic features of children with obesity: body mass index predict severe obstructive sleep apnea in obese children?
Published 2025-01-01“…Purpose This study aimed to explore the demographic and polysomnographic features of obese children and determine whether body mass index (BMI) could predict severe obstructive sleep apnea (OSA). Methods This cross-sectional study recruited obese children who underwent diagnostic polysomnography between January 2019 and March 2022. …”
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13735
Regional Arterial Stiffness in Patients with Inflammatory Bowel Disease
Published 2019-06-01“…To study muscular (brachial and radial arteries) and elastic (aorta) regional arterial stiffness in IBD patients in comparison with those without IBD, as well as to establish the relationship between arterial stiffness and the characteristics of the IBD course (the duration of illness, severity of attack, activity of systemic inflammation). Materials and methods. The study included 21 IBD patients and 30 patients in the comparison group. …”
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13736
Costs and Resource Use Among Patients with Cervical Cancer, Cervical Intraepithelial Neoplasia, and Genital Warts in Algeria
Published 2022-02-01“…**Objectives:** To describe the patterns and estimate the costs of management of cervical cancer, cervical intraepithelial neoplasia (CIN), and genital warts in Algeria. **Methods:** This was a descriptive analysis of questionnaire data obtained from a panel of 15 oncologists, gynecologists, and dermatologists (n=5 each). …”
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13737
Assessment of ChatGPT-generated medical Arabic responses for patients with metabolic dysfunction-associated steatotic liver disease.
Published 2025-01-01“…The study aimed to explore the potential use of ChatGPT-generated medical Arabic responses for patients with metabolic dysfunction-associated steatotic liver disease (MASLD).<h4>Methods</h4>An English patient questionnaire on MASLD was translated to Arabic. …”
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13738
Enhancing athlete performance under pressure: the role of attribution training in mitigating choking
Published 2025-02-01“…Correct or improve the subjects’ inappropriate attribution of failure results, and enable them to learn to use appropriate and positive attribution, enhance motivation levels, and thus achieve the purpose of improving behavior and performance levels.MethodsThe snowball sampling technique was used to collect data through the combination of online electronic questionnaires and offline paper questionnaires, so as to explore the choking phenomenon of elite athletes by attributing the influence of training variables on self-efficacy. …”
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13739
Transition characteristics and driving mechanisms of different types of rural settlements in plain agricultural areas
Published 2025-01-01“…[Objective] Exploring the transformation characteristics of rural settlements can enrich the research system of land use transformation and is of great significance for promoting the comprehensive revitalization of rural areas and the reconstruction of rural space. [Methods] Based on the differential manifestations of rural at the regional and village scales, This paper systematically analyzed the morphological characteristics, transformation process, and driving mechanisms of rural settlements from both the “point” and “plane” perspectives, furthermore, a comparative study was conducted on four typical villages in Fangsi Town, Yucheng City, the plain agricultural area in Shandong Province: urban-rural integrated, agglomeration-enhanced, characteristic development, and preservation-improvement types. …”
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13740
A Contemporary Analysis of Discharge Disposition Following Total Joint Arthroplasty
Published 2025-02-01“…Examining preoperative patient characteristics of those who are still admitted to SNFs, despite cultural shifts, may help providers identify patients still at high risk for SNF discharge. Methods: This retrospective study included patients who had elective total hip arthroplasty or total knee arthroplasty from January through December 2022 at a high-volume orthopaedic institute. …”
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