Effectiveness of Single-Tablet Combination Therapy in Improving Adherence and Persistence and the Relation to Clinical and Economic Outcomes by Carly J. Paoli, Jörg Linder, Khushboo Gurjar, Deepika Thakur, Julie Wyckmans, Stacy Grieve

“…**Objectives:** We conducted a systematic literature review (SLR) to examine STCT-associated outcomes across 4 evidence domains: clinical trials, real-world evidence (RWE), health-related quality of life (HRQoL) studies, and economic evaluations. **Methods:** Four SLRs were conducted across the aforementioned domains. …”
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Healthcare Resource Utilization and Cost Comparisons of High-Protein Enteral Nutrition Formulas Used in Critically Ill Patients by Matthew C. Bozeman, Laura L. Schott, Amarsinh M. Desai, Mary K. Miranowski, Dorothy L. Baumer, Cynthia C. Lowen, Zhun Cao, Krysmaru Araujo Torres

“…**Objective:** The study goal was to compare healthcare resource utilization (HCRU) and cost between immunonutrition and StdHP using real-world evidence from a large US administrative database. **Methods:** A retrospective cohort study was designed using the PINC AI™ Healthcare Database from 2015 to 2019. …”
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SLC7A11 is a potential therapeutic target and prognostic biomarker correlated with immune cell infiltration in cervical cancer by Mutangala Muloye Guy, Tingting Bian, Longyun Sun, Yiping Hao, Xinlin Jiao, Wenjing Zhang, Teng Zhang, Baoxia Cui

“…By utilizing bioinformatics and in vitro validation, we explored SLC7A11's role in cervical cancer. Methods From the TCGA database, we analyzed SLC7A11 expression profiles and validated its promoting role in cervical cancer by in vitro. …”
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Similarities and Differences between Coronavirus Disease 2019-related Multisystem Inflammatory Syndrome in Children and Kawasaki Disease in Indian Patients by Utkarsh Singh, Suhas Prabhu, Deepak Phalgune

“…The present study was conducted to describe the similarities and differences between MIS-C and KD which may help in diagnosis. Materials and methods: This prospective observational and retrospective study was conducted between April 2022 and March 2023. …”
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Estimation of antioxidant and hypolipidemic activities of extracts of Citrus x aurantium leaves in vitro by Loulia Al Hawat, Loai Alallan

“…Objective: This study was done to estimate the antioxidant and hypolipidemic activities of three extracts of Citrus x aurantium var. amara L. leaves, and to determine the total phenolic and flavonoids contents, as well as to find the relationship between leaves’ chemical (phenolic and flavonoids) content and their biological activities. Methods: Three different extracts were prepared using distilled water, ethanol 70 %, and n-hexane. …”
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Effect of weight loss on the course of non-alcoholic fatty liver disease: results of 6-month follow-up by L. V. Chesnokova, I. M. Petrov, I. A. Troshina, M. V. Goncharova, I. V. Medvedeva

“…To study the effect of nonpharmaceutical correction of body weight on the level ofhigh cardio-vascular risk markers at non-alcoholic fatty liver disease (NAFLD).Material and methods. Overall 117 patients with NAFLD at steatosis stage combined to obesity or metabolic syndrome (MS) — 59 and 58 patents respectively, mean age 43 years (38 to 46 years) and 45 years (39- 49) were investigated. …”
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Changing trends in human brucellosis in pastoral and agricultural China, 2004–2019: a Joinpoint regression analysis by Xiaojuan Ma, Zhuo Liu, Yuhui Geng, Yuan Zhao, Hua Meng, Mingbo Chen, Ting Pan, Dongfeng Pan, Peifeng Liang

“…It sought to identify factors contributing to higher incidence rates at specific times and to compare incidence trends across pastoral, agricultural/pastoral, and agricultural areas. Methods Annual and monthly incidence and numbers of reported cases of human brucellosis in regional China between 2004 and 2019 were accessed from the National Public Health Science Data Sharing Center, and the annual percentage change (APC) in pastoral and agricultural areas was calculated. …”
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Relationship between physical literacy and mental health in adolescents: a moderated mediation model with resilience and physical activity as variables by Zhu Shanshan, Tao Ping, Lin Jiabin, Liu Tianzhuo, Lai Xiaomei, Wang Bolei, Dai Leifu, Tang Jianfeng

“…IntroductionPhysical literacy is defined as the motivation, confidence, physical competence, knowledge, and understanding to value and take responsibility for engaging in physical activities for life, and may be associated with higher mental health; however, few studies have explored the processes underlying these positive associations.ObjectivesThe present study aimed to explore the role of resilience in the relationship between physical literacy and mental health, and further examines the mediating role of physical activity.MethodsThis cross-sectional study recruited a sample of 1,022 (aged 10–18 years, Mage = 14.84, SD = 1.79, 44.9% male) Chinese students, grades five to twelve, via physical education courses. …”
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Unhealthy alcohol use and risk of coronary heart disease among young and middle-aged adults by Jamal S. Rana, Felicia W. Chi, Isaac Acquah, Stacy A. Sterling

“…Objective: To examine the associations between unhealthy alcohol use and risk of coronary heart disease (CHD) among women and men aged 18–65 years. Methods: An observational study in an integrated healthcare system with systematic alcohol screening. …”
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Phytochemistry and pharmacological advances of Ascophyllum nodosum in the management of human diseases: A comprehensive review by Brijesh Singh Chauhan, Yash Pal Singh

“…Purpose: This comprehensive review divulges the existing knowledge from research literature on Ascophyllum nodosum extract (ANE) and offers suggestions for future research on its potential against human diseases. Methods: To ensure a comprehensive search, we reviewed peer-reviewed articles on Ascophyllum nodosum extract (ANE) and its active constituents using several online databases, including Google Scholar, PubMed, ResearchGate, and Web of Science. …”
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PROMETHEUS: Long-Term Exacerbation and Mortality Benefits of Implementing Single-Inhaler Triple Therapy in the US COPD Population by Gerard Criner, Fernando Martinez, Hitesh Gandhi, Norbert Feigler, Bruce Pyenson, Matthew Emery, Umang Gupta, Muthiah Vaduganathan

“…**Objectives:** This simulation-based projection aimed to estimate the potential impact of widespread SITT use on the US COPD population. **Methods:** Exacerbation and all-cause mortality reductions reported in the Efficacy and Safety of Triple Therapy in Obstructive Lung Disease trial (ETHOS; NCT02465567) were used to project clinical outcomes in US patients meeting ETHOS trial eligibility criteria (ETHOS-Eligible) and patients meeting a practical definition of SITT eligibility (Expanded ETHOS-Eligible). …”
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Enhancing anthropometric proficiency: Effect of a structured training program on skills of Anganwadi workers in rural areas of Raebareli District, Uttar Pradesh by Mukesh Shukla, Abhay Singh, Sourabh Paul, Mritunjay Kumar, Ravinder Singh Bedi

“…Settings and Design: A community-based interventional study, was conducted among 162 AWWs, 73 from Salon and 89 from Rahi development blocks of Raebareli district. Methods and Material: The skills of AWWs in anthropometric measurement domains (weight, height/length, and mid-upper arm circumference) were assessed using a pre-tested observatory checklist both before and after the training sessions. …”
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Multimorbidity in Atherosclerotic Cardiovascular Disease and Its Associations With Adverse Cardiovascular Events and Healthcare Costs: A Real-World Evidence Study by Dingwei Dai, Joaquim Fernandes, Xiaowu Sun, Laura Lupton, Vaughn W. Payne, Alexandra Berk

“…**Objective:** To assess the multimorbidity burden and its associations with adverse cardiovascular events (ACE) and healthcare costs among patients with ASCVD. **Methods:** This is a retrospective observational cohort study using Aetna claims database. …”
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Glycemic Profile and Clinical Treatment in Patients with Diabetes Mellitus-Tuberculosis: An Update Scoping Review by Rissaadah S, Nursiswati N, Pahria T

“…The secondary aim of this study was to explore the association between DM-TB, successful treatment, and TB severity.Methods: This study used a scoping review following the Arksey and O’Malley framework to provide an overview of glycemic control and clinical treatment of DM-TB. …”
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Hepatoprotective Effects of Nasturtium Officinale and Allium Polyanthum Extracts on CCL4- Induced Hepatic Damage In Albino Rats by Shkar Rzgar K.Rostam, Zana Hassan Ibrahim, Rebaz Rebwar Mala, Soran Qadir Abdul

“…The aim: This study was designed to explore the potential hepatoprotective effects of Nasturtium officinale and Allium polyanthum plant extracts against CCl4-induced hepatic injury in rat model. Methods: Thirty healthy male albino rats were equally divided into 5 groups: Normal control (NC), Positive control (Pos-C), Nasturtium officinale extract (NOE), Allium polyanthum extract (APE), and NOE + APE. …”
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Effect of Intradiscal Methylene Blue Injection in Endoscopic Transforaminal Lumbar Discectomy by Sankarnath Pirabakaran, Babu Aloy, Manikandan Pavanasam

“…Aim and objective: To evaluate the functional outcome of methylene blue injection in the endoscopic transforaminal lumbar discectomy in lumbar disc disease patients and clinical improvement in the form of postoperative (postop) radicular pain relief, early return to daily activities, and occupation. Materials and methods: A mixture of 1 mL 1% methylene blue and 1 mL 2% lidocaine. …”
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Signs of Nervous System Sensitization in Female Runners with Chronic Patellofemoral Pain by Brian J. Eckenrode, David M. Kietrys, Allison Brown, J. Scott Parrott, Brian Noehren

“… # Study Design Cohort Study # Methods Twenty healthy female runners and 17 female runners with chronic PFP symptoms were enrolled. …”
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Molecular characterization and potential therapeutic roles of miR125a in HER-2 positive gastric cancer by Afraa Mamoori, Zena Hasan Sahib, Haider Alkafaji

“…This study aimed to investigate the expression pattern of miR-125a-3p, identify the expression level of its target gene in gastric carcinoma, and test its effect in HER-2 positive gastric carcinoma cells. Materials and Methods: The levels of miR-125a-3p in both cancer and noncancer tissues were measured by using Quantitative real-time polymerase chain in 70 gastric carcinomas. …”
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Impact of One Year Covid-19 on Hand and Upper Extremity Injury: A Cross-Sectional Study by Pamudji Utomo, Tito Sumarwoto, Naufal Aminur Rahman, Mochammadsyah Beizar Yudhistira

“…This research aimed to see how COVID-19 affected hand and upper extremity injuries. Methods: The observational cross-sectional research was undertaken from March 2019 to February 2021. …”
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Effects of balanced opioid-free anesthesia on post-operative nausea and vomiting in patients undergoing video-assisted thoracic surgery: a randomized trial by Xiang Yan, Chen Liang, Jia Jiang, Ying Ji, An-Shi Wu, Chang-Wei Wei

“…We tested the hypothesis that balanced opioid-free anesthesia (OFA) might reduce the incidence of PONV after video-assisted thoracic surgery. Methods One hundred and sixty-eight adults undergoing video-assisted thoracic assisted surgery were randomly assigned to receive balanced opioid-free anesthesia or balanced opioid-based anesthesia (OBA). …”
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