Prevalence and predictors of severe Crohn’s disease at a tertiary hospital in South Africa by C Gounden, V Naidoo, Y Moodley

“…Objective To determine the prevalence and predictors of SCD in a sample of South African patients. Methods This was a retrospective chart review of patients with Crohn's disease (CD) attending the Gastroenterology Unit at a tertiary hospital in Durban, South Africa. …”
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Association of dietary niacin intake with all-cause mortality in chronic kidney disease: A retrospective cohort study of NHANES. by Meijuan Xiang, Jianyun Peng, Zhihong Gui, Ju Jin, Jinling Meng

“…The study would explore the association between dietary niacin intake and all-cause mortality in CKD patients.<h4>Methods</h4>Data about 4,659 CKD patients in this retrospective cohort study were obtained from the National Health and Nutrition Examinations Survey (NHANES). …”
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The role of sex, age, and BMI in treatment decisions for knee osteoarthritis: conservative management versus total knee replacement by Fabiola Ojeda, Laura Tío, Francisco Castro-Domínguez, Simone Tassani, Jerome Noailly, Jordi Monfort

“…Here we want to identify distinctive characteristics between patients receiving conservative treatment versus total knee replacement (TKR), analyzing both patient-specific and knee-specific features. Methods This case–control study compared patients assigned to TKR versus conservative management, examining subjects aged 60–75 years with radiographically confirmed KOA (Kellgren–Lawrence grades 2–3), with all participants evaluated by blinded clinicians using validated assessment tools including Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Hospital Anxiety and Depression Scale (HADs), Pain Catastrophizing Scale (PCS) and Daily physical activity (DPA) questionnaires. …”
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Role of Platelet-rich Plasma in Unexplained Recurrent Implantation Failure – A Systematic Review and Meta-analysis of Randomised Control Trials by Harpreet Kaur, Meenakshi Meenu, Shivam Pandey, Anil Chauhan, Mishu Mangla

“…Objective: This study has been conducted to summarise the evidence and quality of evidence available so far regarding the role of PRP in cases of unexplained RIF. Materials and Methods: An electronic database search for randomised clinical trials comparing PRP against routine care in women with unexplained RIF was performed on PubMed, EMBASE, SCOPUS and Cochrane Central. …”
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Factors Related to Diet Quality in Adolescent at Yadika 12 High School Depok by Zahra Fadhlina Hidayat, Avliya Quratul Marjan, Utami Wahyuningsih

“…Objectives: This study analyzes the factors related to diet quality among adolescents at Yadika 12 High School Depok. Methods: This quantitative study used a cross-sectional design conducted at Yadika 12 High School Depok with 108 respondents selected using stratified random sampling. …”
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Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters by Yongjun Sui, Swagata Kar, Bhavna Chawla, Tanya Hoang, YuanKai Yu, Shannon M. Wallace, Hanne Andersen, Jay A. Berzofsky

“…As a subunit intranasal COVID-19 vaccine reduced nasopharyngeal virus more than did an intramuscular (IM) vaccine, we hypothesized that this vaccine might reduce onward transmission to others.MethodsWe vaccinated hamsters with either the IM-administrated licensed mRNA vaccine twice or one dose of mRNA IM followed by adjuvanted subunit intranasal vaccine. 24 hours after SARS-CoV-2 challenge, these animals were housed with naïve recipients in a contactless chamber that allows airborne transmission.ResultsOnward airborne transmission was profoundly blocked: the donor and recipients of the intranasal vaccine-boosted group had lower oral and lung viral loads (VL), which correlated with mucosal ACE2 inhibition activity. …”
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Undernutrition and associated factors among incarcerated people in Bahir Dar and Finote Selam prison sites, Northwest Ethiopia: a cross-sectional study by Hiwot Tesfa, Alemayehu Tarekegn, Mulunesh Alemayehu, Habtamu Temesgen, Hunegnaw Almaw Derseh

“…Incarcerated peoples’ dependency on the prison-limited food menu, inadequate meal provision and poor-quality food increases the risk of malnutrition.Objective To assess the magnitude of undernutrition and associated factors among incarcerated people, Northwest Ethiopia, 2019.Design An institution-based cross-sectional study was conducted in Bahir Dar and Finote Selam prison sites, in Northwest Ethiopia.Methods This study was conducted from 18 March 2019 to 18 April 2019. 475 systematically selected incarcerated people from each prison site were included in this study. …”
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Translation, cross-cultural adaptation and validation of the composite physical function scale in Chinese community-dwelling older adults by Jiaying Qi, Jing Xu, Hui Zhang, Mingshuai Feng, Hongyan Meng, Li Wang

“…Abstract Purpose To translate, cross-culturally adapt and validate the Composite Physical Function (CPF) scale in Chinese community-dwelling older adults. Methods The Chinese version of the CPF (C-CPF) was constructed by following Brislin’s guidelines. …”
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Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Erdafitinib vs Enfortumab Vedotin in Patients with Locally Advanced Metastatic Urothelial Carcinoma by Suzy Van Sanden, Ayman Youssef, Simona Baculea, Keith Stubbs, Spyros Triantos, Zijiao Yuan, Caitlin Daly

“…**Objective:** To compare the efficacy and safety of erdafitinib vs enfortumab vedotin-ejfv (EV) in the absence of head-to-head comparison via an anchored matching-adjusted indirect comparison (MAIC). **Methods:** An anchored MAIC was conducted according to the National Institute for Health and Care Excellence Decision Support Unit guidance, with physician’s choice of chemotherapy (docetaxel/paclitaxel and vinflunine) as the common comparator. …”
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Early childhood caries and their association with serum iron, serum ferritin, serum albumin, and Vitamin D by Vasundhara Megha, Jeevendra Nath Shukla, Rajat Kumar Singh, Chitrita Gupta Mukherjee, Siddharth Anand, Aparna Singh

“…Aim: The present study aimed to correlate the association between serum iron, serum ferritin, serum albumin, and Vitamin D with early childhood caries (ECC). Materials and Methods: This study was a single-blinded randomized control trial. …”
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Effect of power training on physical functional performance of patients with Parkinson's disease: A systematic review and meta-analysis of randomized controlled trials. by Samuel Brito de Almeida, Emmanuelle Silva Tavares Sobreira, Charles Phillipe de Lucena Alves, Danielle Pessoa Lima, Janine de Carvalho Bonfadini, Manoel Alves Sobreira-Neto, Thiago Holanda Freitas, Simony Lira do Nascimento, Pedro Braga-Neto

“…<h4>Objective</h4>To compare the effect of PT versus control or other physical activity (PA) interventions on physical functional performance (PFP) in PD patients.<h4>Methods</h4>We searched PubMed, MEDLINE, Embase, LILACS, PEDro, Cochrane Library, and Scopus. …”
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Efficacy and safety of camrelizumab combined with chemotherapy as second-line treatment for locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma by Yinfang Gu, Xiaofang Zou, Junlin Zhu, Guowu Wu

“…Abstract Background This study aims to evaluate the efficacy and safety of camrelizumab in combination with chemotherapy as a second-line treatment for patients with locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma (ESCC). Methods In this retrospective, single-center observational study, we collected medical records of patients with locally advanced, recurrent, or metastatic ESCC who received either camrelizumab combined with chemotherapy or chemotherapy alone as second-line treatment between July 1, 2019, and May 31, 2023. …”
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Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

“…Hence, it is necessary to investigate the potential of medication history as a predictor of survival outcomes among AKI patients in the intensive care unit (ICU). Methods Critically ill AKI patients were sourced from the MIMIC-IV database. …”
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A Preseason Training Program With the Nordic Hamstring Exercise Increases Eccentric Knee Flexor Strength and Fascicle Length in Professional Female Soccer Players by Karoline Baptista Vianna, Lívia Gonçalves Rodrigues, Nathalia Trevisol Oliveira, João Breno Ribeiro-Alvares, Bruno Manfredini Baroni

“… # Study Design Quasi-experimental study. # Methods Sixteen amateur female soccer players (without a NHE training routine) were evaluated 8-weeks apart to: (1) assess reliability of eccentric knee flexor strength and biceps femoris fascicle length measures; and (2) determine the typical error of measures that would be used to discriminate training responders and non-responders. …”
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Cost-benefit analysis of VKA versus NOAC treatment in German patients with atrial fibrillation utilizing patient self-testing by Roland Diel, Niklas Lampenius

“…**Objective:** To assess the cost-benefit by implementing patient self-testing (PST) in German patients anticoagulated with vitamin K antagonists (VKA) compared to treatment with the new oral anticoagulant drugs (NOAC) apixaban, dabigatran, edoxaban, and rivaroxaban. **Methods:** A deterministic decision-analytic model was developed simulating the number of major bleedings, ischemic strokes, and hemorrhagic strokes and their associated costs by utilizing PST compared to those of treatment with NOAC. …”
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RESILSTIGMA. Resilience to self-stigmatization experienced by people living with HIV: Which self-reported factors improve awareness among health workers? by Christine Jacomet, Cécile Miele, Emilie Goncalves, Céline Lambert, Clément Belletier, Françoise Linard, Josiane Phalip-Le Besnerais, Pierre Dellamonica, Michaël Dambrun

“…The aims of our study were to investigate the psychological, social and medical factors, in particular psychological flexibility and its defusion component, that are associated with resilience to self-stigmatization in people living with HIV (PLHIV), and to assess clinicians' perceptions of the condition.<h4>Methods</h4>A multicenter observational study was conducted in France using self-reports from PLHIV consulted between January 15, 2022 and June 15, 2022 and from professionals responsible for their care (study registration number 2021-A01588-33/SI:21.02814.000036). …”
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Central obesity is a burden even in normal weight adolescents of a non-metropolitan Indian City: A case for alarm and action for prevention and control by Tabassum Nawab, Zulfia Khan, Iqbal M. Khan, Mohammad A. Ansari

“…Objectives: (1) To estimate the prevalence of central obesity in school-going adolescents, (2) To determine the association between central obesity and generalized obesity (GO) among adolescents, and (3) To determine the correlates of central obesity. Methods: Totally, 660 adolescents, selected using systematic random sampling, in four urban schools in Aligarh were interviewed using pre-designed questionnaire and Global Physical Activity Questionnaire. …”
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Randomised control trial to compare the efficacy of traditional Thai massage and ultrasound therapy for treating plantar heel pain by Supamas Somphai, Wiraphong Sucharit, Punnee Peungsuwan, Neil Roberts, Uraiwan Chatchawan

“…In the present study Traditional Thai Massage (TTM) has been compared with Ultrasound therapy (US) for treating PHP. Methods Sixty PHP patients with a Myofascial Trigger Point (MTrP) present in the calf were randomly assigned to receive a 40-minute single treatment of either US or TTM. …”
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Prognostic value of FCER1G expression and M2 macrophage infiltration in esophageal squamous cell carcinoma by Wei Peng, Yali Zhao, Ningning Yang, Yan Fang, Yintong Wu, Zhenzhong Feng, Qiang Wu, Xian Wang

“…Our objectives were to study the association between FCER1G and tumor- infiltrating immune cells (TIICs) as well as the predictive significance of FCER1G. Methods The expression of FCER1G and its prognostic value in ESCC was examined by The Cancer Genome Atlas and Gene Expression Omnibus databases. …”
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Comparative Pitching Biomechanics Among Adolescent Baseball Athletes: Are There Fundamental Differences Between Pitchers and Non-pitchers? by Garrett Bullock, Tessa C Hulburt, Gary Collins, Brian R Waterman, Kristen F Nicholson

“… # Study Design Retrospective cross-sectional study # Methods Baseball players were designated as pitchers or non-pitchers, who then threw fastballs (FB), breaking balls (BB), and change-ups (CH) during a biomechanical assessment. …”
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