Sub-Clinical Regional Macular Changes in Self-Reported Diabetic Subjects: Vascular and Retinal Layer Analysis Using Swept-Source OCT by Challa NK, Alghamdi WM, Alluwimi MS, Alshammeri S

“…Naveen Kumar Challa, Waleed M Alghamdi, Muhammed S Alluwimi, Saleh Alshammeri Department of Optometry, College of Applied Medical Sciences, Qassim University, Buraidah, AlQassim, Saudi ArabiaCorrespondence: Naveen Kumar Challa, Department of Optometry, College of Applied Medical Sciences, Qassim University, Buraidah, AlQassim, Saudi Arabia, Tel +966531177518, Email N.challa@qu.edu.saAim: To assess and compare subclinical alterations in superficial capillary plexus vessel density (SCPVD) and retinal layers thickness in the macular region between individuals with type 2 diabetes mellitus (DM) and healthy controls.Methods: Swept-source OCT images were obtained from 29 control subjects and 24 diabetic subjects. …”
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Efficacy of vericiguat in patients with chronic heart failure and reduced ejection fraction: a prospective observational study by Yinge Zhan, Liu Li, Jie Zhou, Yishan Ma, Xuchong Guan, Suo Wang, Ya Chang

“…Abstract Objectives This study aims to evaluate the therapeutic effect of Vericiguat through cardiopulmonary exercise testing (CPET) in patients with chronic heart failure and reduced ejection fraction (HFrEF). Methods A prospective observational study was conducted from May 2022 to May 2023, focusing on patients with HFrEF admitted to our hospital. …”
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RETRACTED ARTICLE: Single-cell omics and machine learning integration to develop a polyamine metabolism-based risk score model in breast cancer patients by Xiliang Zhang, Hanjie Guo, Xiaolong Li, Wei Tao, Xiaoqing Ma, Yuxing Zhang, Weidong Xiao

“…The metabolic pathway of polyamines is crucial in breast cancer progression, with a strong association to the increased capabilities of tumor cells for proliferation, invasion, and metastasis. Methods We used a multi-omics approach combining bulk RNA sequencing and single-cell RNA sequencing (scRNA-seq) to study polyamine metabolism. …”
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Characterizing the Flow and Interaction of Microbubbles in a 2D Capillary Network for Targeted Drug Delivery: A Simulation Study by Sadegh Shurche, Akram Shahidani, Roghaye Bodaghi Hossein Abadi

“…The evaluated network mimics part of a capillary system by comprising multiple bifurcations. Materials and Methods: We designed the capillary network based on the tree pattern employed in quantitative studies per Murray’s minimum work rule and the cardiovascular network to simulate the hemodynamics of the vessels. …”
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Osteoarthritis of the knee joint and its association with metabolic syndrome: A case control study by Rohini Motwani, Arvind Kumar Bodla, Shravan Kumar Peddamadyam, Mrudula Chandrupatla, Nagesh Cherukuri, Maheshwar Lakkireddy, Gunvanti Rathod, Sai Ram Challa, Chowdavarapu Raghavendra Rao, Abhishek Arora, Srikanth Eppakayala, Arcot Reddy Vamsi Krishna

“…Data collection was done including demographic details, medical history, physical examinations, and laboratory tests. …”
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Characteristics of paediatric burn injuries seen in the tertiary emergency centre, South Africa by Ntsovelo Mugwena, Rule Human, Maria M. Geyser

“…This study aimed to determine the characteristics and referral patterns of burn injuries. Methods: A retrospective observational study was conducted in a single emergency centre, Kalafong Provincial Tertiary Hospital, from 01 January 2021 to 31 December 2021. …”
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Assessing the impact of long-term inhaled corticosteroid therapy on patients with COVID-19 and coexisting chronic lung disease: A multicenter retrospective cohort study by Adela Pina Belmonte, Manuel Madrazo, Laura Piles, Manuel Rubio-Rivas, Lucía de Jorge Huerta, María Gómez Antúnez, Juan Francisco López Caleya, Francisco Arnalich Fernández, Martin Gericó-Aseguinolaza, Paula Maria Pesqueira Fontan, Nicolás Rhyman, Marina Prieto Dehesa, Juan Luis Romero Cabrera, Gema María García García, Gonzalo García-Casasola, Ane Labirua-Iturburu Ruiz, Francisco Javier Carrasco-Sánchez, Sara Martínez Hernández, Maria de los Reyes Pascual Pérez, José López Castro, José Luis Serrano Carrillo de Albornoz, José F. Varona, Ricardo Gómez-Huelgas, Juan-Miguel Antón-Santos, Carlos Lumbreras-Bermejo

“…The main objective of this study is to know the influence of chronic treatment with ICS on the prognosis of COVID-19 hospitalized patients with CLD. # Methods A multicenter retrospective cohort study was designed, including patients hospitalized with COVID-19. …”
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EXPERIENCE OF USING PLANET EARTH OBSERVATION DATA IN RETRAINING COURSES FOR EDUCATORS IN THE JUNIOR ACADEMY OF SCIENCES OF UKRAINE by Stanislav O. Dovgyi, Svitlana M. Babiichuk, Olha V. Tomchenko

“…The paper presents a detailed description of one of the hands-on case studies of water bodies in EO-Browser. …”
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Psychosocial work characteristic profiles and health outcomes in registered nurses at different stages of their careers: a cross-sectional study by Katri Lönnqvist, Timo Sinervo, Anu-Marja Kaihlanen, Marko Elovainio

“…The purpose of this study was to identify latent psychosocial work characteristic profiles and examine whether the profiles are associated with a certain career stage and health outcomes. Methods This cross-sectional study was conducted with 624 early-career registered nurses and 1,016 later-career registered nurses. …”
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Efficacy of Trimebutine Maleate (Trimedat®) in the Treatment of Patients with Functional Dyspepsia: Results of the “TREND” Observational Study by S. S. Kardasheva, I. M. Kartavenko, N. B. Maksimova, E. Yu. Yurieva, I. R. Popova, Ch. S. Pavlov, V. T. Ivashkin

“…This research is aimed at investigating the experience of applying trimebutine maleate in the daily practice of physicians managing patients with functional dyspepsia syndrome (FDS).Materials and methods. The study included 100 patients diagnosed with FDS. …”
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An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors by Russell J. Schilder, Drew Rasco, Manish R. Sharma

“…This first-in-human trial evaluates ESK-440, a dual inhibitor of ALK and focal adhesion kinase, as a novel strategy for cancers with resistance to ALK-targeting TKIs. Methods: This phase 1, open-label, dose-finding study evaluated the maximum tolerated dose (MTD), safety, efficacy, and pharmacokinetics of ESK-440 in participants with advanced or metastatic solid tumors (ClinicalTrials.gov: NCT01922752). …”
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Environmental effects of urban wind energy harvesting: a review by Ioannis Tsionas, Maider Llaguno-Munitxa, André Stephan

“…Given the heterogeneity of urban conditions, the implementation of SUWTs requires detailed local environmental assessment to characterise accurately most environmental effects, notably the net life-cycle primary energy performance and associated GHG emissions, raw materials depletion, recycling, safety, noise, visual and light pollution, and effects on urban wildlife. …”
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Social media use is associated with body image concern in young adults during the COVID-19 pandemic by Marina de Sá Azevedo, Brenda Esper-Pereira, Larissa Vaz-Gonçalves, Raquel Machado Schincaglia, Marília Mendonça Guimarães, Karine Anusca Martins, Luciana Bronzi de Souza

“…Thus, the aim of this study is to examine the relationship between social media use and body image concerns among young adults during the COVID-19 pandemic. Methods: Cross-sectional study conducted with 461 young adults (18-30yrs), from Midwest Brazil, who answered an online and self-reported questionnaire to determine the social media use, with questions about time of service, frequency of access, and media influence on behaviors. …”
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Assessing medical students’ beliefs about the opioid crisis and their post-graduation plans: a cross-sectional study by Samuel Borgemenke, Nicholas Durstock, Elizabeth A. Beverly

“…To investigate medical students’ beliefs about the opioid crisis and their post-graduation plans from two medical schools in the United States. Methods 312 students from one medical school with three campuses were surveyed on their experiences, beliefs, and the impacts that the opioid crisis has had on their lives and their medical training. …”
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New Composite Indexes through Factor Analysis Simplifying the Interpretation of Health-Related Quality of Life Outcomes of Surgical Adolescent Idiopathic Scoliosis Patients Complet... by Wai-Wang Chau, Bobby Kin-Wah Ng

“…In view of a total of 14 (9 + 5) major domain scores from both questionnaires, this study attempted to develop new composite indexes using factor analysis. Materials and Methods: All operated AIS patients within the years 2014 and 2016 were recruited. …”
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Protein hydrolysate as an efficient and environmental-friendly swelling inhibitor in clay formations by Yahya Dashti-Rahmatabadi, Hamid Saeidian, Javad Mokhtari, Zohreh Mirjafary

“…The findings from various analytical methods suggest that amino acids, peptides, and polypeptides in the HPC interact with clay surfaces, rendering them hydrophobic and impeding swelling. …”
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Microbiological And Physicochemical Analyses Of Oil Contaminated Soil From Major Motor Mechanic Workshops In Benin City Metropolis,Edo State, Nigeria by FO Ekhaise, J Nkwelle

“…Soil samples collected from the three major mechanic workshops at Igun, Evbareke and Uwelu Quarters in Benin City were analyzed for the microbiological and physicochemical qualities using the basic microbiological methods. The total heterotrophic bacterial counts from the three mechanic workshops ranges from 1.98 X 107 to 2.95 X 107cfu/g while the total heterotrophic fungal counts ranges from 6.7 X 106 to 9.2 X 106 cfu/g. …”
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Dyslipidaemia in patients with chronic kidney disease – a neglected cardiovascular risk factor by M R Essop, F Seedat, F J Raal

“…To determine the prevalence and control of dyslipidaemia in a cohort of SA patients with CKD. Methods. A retrospective, cross-sectional observational study of 250 patients with CKD attending the Charlotte Maxeke Johannesburg Academic Hospital renal clinic from 1 July 2019 to 31 July 2020 was carried out. …”
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Cost-Effectiveness of the CNIC-Polypill Strategy Compared With Separate Monocomponents in Secondary Prevention of Cardiovascular and Cerebrovascular Disease in Portugal: The MERCUR... by Carlos Aguiar, Francisco Araujo, Gabriel Rubio-Mercade, David Carcedo, Silvia Paz, Jose María Castellano, Valentín Fuster

“…**Objectives:** To assess the cost-effectiveness of a CV polypill strategy (CNIC-Polypill) compared with the loose combination of monocomponents to improve the control of CV risk factors in patients with previous coronary heart disease or stroke. **Methods:** A Markov model cost-utility analysis was developed using 4 health states, SMART risk equation, and 3-month cycles for year 1 and annual cycles thereafter, over a lifetime horizon from the perspective of the National Health System in Portugal (base case). …”
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Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers by Aketilieke Nusufujiang, Mulalibieke Heizhati, Nanfang Li, Ling Yao, Wenbo Yang, Hui Wang, Mei Li, Lin Gan, Adalaiti Maitituersun, Miaomiao Liu, Qiaolifanayi Nuermaimaiti, Li Cai, Xiayire Aierken, Xiufang Li, Qin Luo, Jing Hong

“…Therefore, we aimed to explore whether PAC is associated with cognitive performance in this population.MethodsWe cross-sectionally enrolled adults using multistage random sampling from Emin, China in 2019. …”
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