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11921
A comprehensive insight of innovations and recent advancements in nanocarriers for nose-to-brain drug targeting
Published 2025-12-01“…Central Nervous System (CNS) disorders are the leading cause of illness and affect the everyday lives of people all around the globe and are predicted to increase tremendously in the upcoming decades. Traditional methods of delivering drugs to the CNS face considerable limitations. …”
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11922
Molecular genetic factors influencing outcomes of <i>Helicobacter pylori</i> infection at Khakasia republic inhabitants
Published 2010-08-01“…To detect molecular-genetic features of Helicobacter pylori and polymorphism of main immunoregulatory interleukins genes at Khakases, to estimate their effect on outcomes of infection pathogen.Material and methods. Investigation was carried out at native population of Khakasia with H. pyloriassociated diseases: peptic ulcer and chronic gastritis. …”
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11923
Does the 2D Frontal Plane Projection Angle Predict Frontal Plane Knee Moments during Stepping, Landing, and Change of Direction Tasks?
Published 2022-12-01“… # Design Crossover Study Design. # Methods Three-dimensional lower-extremity kinetics and 2D video were obtained from 39 healthy athletes (15 males and 24 females) during execution of six tasks (step down, drop jump, lateral shuffle, deceleration, triple hop, side-step-cut). …”
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11924
Does the consumption of soya products affect cholesterol levels, blood pressure, or other cardiovascular health indicators?
Published 2025-02-01“…Aim of the study This study aims to analyse the current state of knowledge regarding the effect of soy consumption on: hypertension, lipid profile, biomarkers of inflammation, vascular epithelium and impact on mortality caused by cardiovascular diseases. Material and methods For this review, we analyzed articles that we found in Pubmed and Google Scholar and that were related to our topic. …”
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11925
Accuracy of Intraoperative Transesophageal Echocardiographic Doppler Parameters in Assessing the Right Ventricular Diastolic Function After Repair of Tetralogy of Fallot in Pediatr...
Published 2025-01-01“…Background: This study aimed to assess the accuracy of tricuspid spectral Doppler (E/A) and tissue Doppler parameters (E/E’) to diagnose right ventricular diastolic dysfunction (RVDD) in comparison to American Society of Echocardiography (ASE criteria) in pediatric tetralogy of Fallot (TOF) patients after surgical repair. Methods: This prospective, observational study was done at a tertiary care hospital involving 40 pediatric TOF patients aged less than 2 years who underwent complete intracardiac repair with cardiopulmonary bypass (CPB). …”
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11926
Prospective observational study of oral clonazepam to prevent high-dose busulfan-induced seizures in adult patients
Published 2025-02-01“…The secondary objectives were to determine the feasibility of this regimen and to analyze the adverse events associated with the use of clonazepam. Methods This prospective, single-center study included 64 adult patients who received conditioning regimens with high doses of intravenous busulfan and anti-seizure prophylaxis with oral clonazepam, at a dose of 1 mg/8 h, from 12 h before starting treatment with busulfan until 48 h after ending administration. …”
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11927
Hybrid quantum neural networks show strongly reduced need for free parameters in entity matching
Published 2025-02-01“…Hence, entity matching, i.e. the process of linking data about a given entity gathered from multiple data sets, is a major problem in artificial intelligence with applications in science and industry. Typical methods for entity matching either use specialized algorithms or supervised machine learning. …”
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11928
‘Underestimation of fall risks by older adults: The need for professional evaluation to identify home hazards’
Published 2025-03-01“…Objective: This study aims to analyze the extent to which Brazilian older adults accurately perceive fall risks in their home environment, emphasizing the potential gap between self-perception and actual hazards. Methods: 90 older adults were assessed through home visits using the Home Safety Self-Assessment Tool (HSSAT), an American instrument adapted for the Brazilian context. …”
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11929
The molecular dynamics study of the thermal behavior of argon flow in a nanochannel with changes in nanochannel cross-section
Published 2025-03-01“…This research is simulated in three-dimensional space using molecular dynamics methods using computer code. The results of this research show that, the increase in the number of wall atoms in a three-dimensional nanochannel causes a greater depletion of fluid kinetic energy due to the loss of temperature. …”
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11930
Risk Factors and Predictive Model for Disseminated Intravascular Coagulation in Patients with Multiple Myeloma
Published 2025-02-01“…We also sought to develop a predictive formula for assessing DIC risk. Methods A retrospective analysis was conducted on MM patients. …”
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11931
A new negative air ion smoke suppression purifier for purifying fire smoke in road tunnel based on corona discharge
Published 2025-03-01“…Therefore, exploring more effective methods for smoke control is essential. This study evaluates the feasibility of negative air ion purifiers for suppressing tunnel fire smoke through full-scale tests. …”
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11932
Infective Endocarditis - Diagnosis, Treatment and Specific Situations Management – Current Knowledge, Review of the Literature
Published 2025-02-01“…Aim of the study The aim of the study is to review the current knowledge of infective endocarditis and the timing indications of cardiac surgery treatment. Material and methods This article presents the current knowledge of the diagnosis and treatment in infective endocarditis, especially on the basis of the guidelines of European Society of Cardiology. …”
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11933
The involvement of non-governmental organisations in achieving health system goals based on the WHO six building blocks: A scoping review on global evidence.
Published 2025-01-01“…Therefore, this paper examines the role of NGOs in achieving health system goals, based on the six building blocks of a health system framework, and identifies strategies to enhance NGO involvement in achieving health system goals.<h4>Methods</h4>A scoping systematic review methodology was used to map and synthesise the existing literature on the topic, following the latest JBI six-stage framework. …”
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11935
HPV vaccination knowledge, attitude, and practices among physicians in a teaching hospital, Karachi
Published 2025-01-01“…Settings and Design: This is a cross-sectional study carried out with a sample size of 165 among doctors practicing in Family medicine, Internal medicine, Pediatrics, and Gynecology outpatient clinics at a teaching hospital. Methods and Material: Physicians were approached in outpatient clinics, and a pilot-tested coded questionnaire was filled by them. …”
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11936
Taste Dysfunction in COVID-19 Patients; A Cross-Sectional Observational Study
Published 2023-12-01“…Gustatory (taste) dysfunction attributable partly to loss of retro-nasal olfaction (which adds to the flavour, a component of taste sensation) while eating or drinking food. Materials and methods:It is a cross sectional observational study involving COVID-19 patients aged between 18 to 100 years. …”
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11937
Effect of temperature and time on purity, morphology and phase transformations of silica from rice husk
Published 2025-04-01“…In this work, Thermal and chemical treatment methods to synthesize silica from rice husks. The multiple properties of silica sources depend on various calcination temperatures (500–1000 °C) and time (1–6 h) in temperature-controlled muffle furnaces. …”
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11938
A systematic review on the influence of coagulopathy and immune activation on New Onset Atrial Fibrillation in patients with sepsis.
Published 2025-01-01“…The aim of this systematic review and narrative synthesis is to identify inflammatory and coagulation biomarkers as predisposing risk factors for NOAF in sepsis.<h4>Methods</h4>Three databases (Medline, Cochrane Library, and Scopus) were searched using a predefined search strategy. …”
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11939
How value perspectives influence decision-making in the South African private healthcare sector: A cross-sectional comparative study.
Published 2025-01-01“…This cross-sectional comparative study explored the relative importance of 1) clinical outcome, 2) event cost, and 3) patient experience as they relate to the value of care in the South African private healthcare context.<h4>Materials and methods</h4>Using a value perspectives survey, healthcare consumers (n = 662) and healthcare providers (n = 318) distributed 100 points between the three factors according to how they perceived their value. …”
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11940
Lived experiences for individuals with cystic fibrosis who have undergone lung transplantation: a qualitative study
Published 2025-02-01“…While there is existing research on support and information needs post-lung transplant from various perspectives, this study aims to specifically address the unique experiences and challenges faced by individuals with CF during both the pre-transplant and post-transplant periods. Methods Twenty-three lung-transplanted individuals with CF participated in this exploratory qualitative study. …”
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