Gender differences of neurometabolic and neuroendocrine alternations and its lateralization in adolescents with major depressive disorder by Xiaodong Song, Shuya Yan, Shunkai Lai, Yiliang Zhang, Ying Wang, Jiali He, Dong Huang, Jianzhao Zhang, Xiaodan Lu, Guanmao Chen, Pan Chen, Qilin Zhong, Rongxu Zhang, Yangyu Wu, Jie Yin, Shuming Zhong, Yanbin Jia

“…Obtained through 1H-MRS, the N-acetyl aspartate (NAA) and choline containing compounds (Cho) to creatine (Cr) ratios were acquired for the prefrontal whiter matter (PWM), anterior cingulate cortex (ACC), basal ganglia (BG), thalamus, and cerebellum. Result After adjusting for multiple comparisons, female adolescents with MDD showed lower ACTH levels compared to their male counterparts. …”
Get full text

Bilateral pulvinar responsive neurostimulation for bilateral multifocal posteriorly dominant drug resistant epilepsy by Richard Wang, Ariel Sacknovitz, Sima Vazquez, Jose Dominguez, Patty McGoldrick, Steven Wolf, Vishad Sukul, Carrie Muh, Sanjay E. Patra, David E. Burdette

“…Plain Language Summary We describe four cases where stimulation devices were placed in the Pulvinar area of the thalamus (central sensory area in the brain). This is very unique and different location than where these devices are typically placed. …”
Get full text

Resting-State Functional Magnetic Resonance Imaging Study on the Functional Connectivity of Amygdalar Subregions in Patients with Chronic Non-Specific Low Back Pain by CHEN Xiaolin, LIU Hong, GAO Zhen, WU Mengjiao, FAN Cheng, JIANG Zheng

“…Compared with the healthy control group, functional connectivity between the left CM amygdala and right inferior occipital gyrus, between the left SF amygdala and left anterior cingulate cortex, right calcarine fissure &amp; surrounding cortex and left thalamus in the CNLBP group significantly increased (<italic>P</italic>&lt;0.05), but functional connectivity between the left LB amygdala and right angular gyrus, between the right SF amygdala and right hippocampus significantly decreased (<italic>P</italic>&lt;0.05). …”
Get full text

Changes in choroid plexus volume in healthy adults during natural ageing by PANG Huilin, ZHEN Zhiming, ZENG Meng

“…In addition, 3.0T MRI revealed there was a significant positive correlation of CP volume with the volumes of white matter hyperintensities (WMH) and cerebrospinal fluid (P < 0.001), as well as a negative correlation with the volumes of gray matter, white matter, hippocampus and thalamus (P < 0.05). Conclusion CP volume is increased with ageing, with gender differences, independent of field strength and resolution. …”
Get full text

A visual cortical-lateral posterior thalamic nucleus circuit regulates depressive-like behaviors in male mice by Fangfang Wu, Chenxi Gu, Rui Xu, Junwei Ma, Lei Gao, Youjiao Zhang, Siyuan Bu, Qingbo Lu, Te Zhao, Yijun Han, Chen Guo, Yihui Cui, Jianhua Ding, Gang Hu, Zhijun Zhang

“…Here, we demonstrate that the V1, specifically the lateral posterior nucleus of the thalamus (LP)-projecting V1 glutamatergic subpopulation (GluV1→LP neurons), shows reduced activity after chronic restraint stress (CRS) in male mice, leading to depressive-like behaviors. …”
Get full text

Alterations of fractional anisotropy and white matter integrity in irritable bowel syndrome: a systematic review and meta-analysis of diffusion tensor imaging studies by Mahsa Asadi Anar, Aydin Hassanpour Adeh, Aydin Hassanpour Adeh, Samira Peiravi, Alireza Imani Porshokouh, Seyedeh Sara Rezazadeh Shojaee, Farnaz Najafi, Yasamin Pishkari, Arash Rahimi, Shaghayegh Karami

“…Analyzed Standard mean difference using a fixed model for Fractional anisotropy of regions of interest (ROI) associated with sensory processing, such as the thalamus, insula, primary somatosensory cortex, dorsal cingulum and the fornix in selected studies showcased decreased white matter interactivity in case group however this decrease was not statistically different [SMD −88, 95%CI (−1.32, −0.44), p &gt; 0.05].ConclusionFurther investigation is necessary to ascertain whether the modified structural connectivity mentioned in this study is a contributing factor to IBS, an outcome of the condition, a risk factor for it, or, more probably, a consequence of a mutually influential relationship between the changes observed in the white matter tract and IBS symptoms.…”
Get full text

Effects of acupuncture at the Taichong (LIV3) and Hegu (LI4) points on functional connectivity with the retrosplenial cortex in patients with Alzheimer’s disease by Junkai Wang, Xinyue Bai, Xiaojun Chen, Shui Liu, Mengmeng Sun, Kuncheng Li, Yunsong Zheng, Zhiqun Wang

“…Furthermore, multiple brain regions, including the bilateral thalamus, bilateral posterior cingulate cortex (PCC), bilateral subcallosal cingulate gyrus (SCG), bilateral orbitofrontal cortex (OFC), and right precuneus, showed decreased FC with the RSC in the AD group and increased FC with the RSC in the NC group after acupuncture compared to that at baseline. …”
Get full text

Dissociation between Cerebellar and Cerebral Neural Activities in Humans with Long-Term Bilateral Sensorineural Hearing Loss by Xiao-Min Xu, Yun Jiao, Tian-Yu Tang, Jian Zhang, Chun-Qiang Lu, Ying Luan, Richard Salvi, Gao-Jun Teng

“…Voxel-wise functional connectivity (FC) analysis demonstrated decreased couplings between the cerebellum and other cerebral areas, including the temporal pole (TP), insula, supramarginal gyrus, inferior frontal gyrus (IFG), medial frontal gyrus, and thalamus, in long-term bilateral sensorineural hearing loss patients. …”
Get full text

Association between the subclinical level of problematic internet use and habenula volume: a look at mediation effect of neuroticism by Toshiya Murai, Hironobu Fujiwara, Qi Dai, Halwa Zakia, Yusuke Kyuragi, Naoya Oishi, Yuzuki Ishikawa, Lichang Yao, Morio Aki

“…The habenula (Hb), located between the thalamus and the third ventricle, is implicated in various psychiatric disorders. …”
Get full text

Efektivitas Midazolam Untuk Pencegahan Mual Muntah Pascabedah Pada Prosedur Laparaskopi by Jamiludin Jamiludin, Husain AAA

“…Midazolam sebagai agen anti emetik dan  anxiolitik yang  menurunkan sintesis, pelepasan dan efek pasca sinaptik dopamin serta menhambat reuptake adenosin, sehingga menurunkan input dopamin dan 5-HT3 terhadap CRTZ dan mengurangi input dari thalamus yang mempengaruhi langsung pusat muntah. Tujuan: mengevaluasi pemberian midazolam sebagai agen anti emetik dan  anxiolitik Metode: Empat puluh delapan pasien yang akan menjalani prosedur pembedahan laparaskopi elektif secara acak dibagi menjadi dua kelompok. …”
Get full text

Phase I/II trial of intracerebral transplantation of autologous bone marrow stem cells combined with recombinant peptide scaffold for patients with chronic intracerebral haemorrhag... by Arisa Miura, Yoichi M Ito, Masahito Kawabori, Miki Fujimura, Kaoru Kahata, Hideo Shichinohe, Kenichiro Maeda, Masahiko Mukaino, Ryo Kogawa, Kentaro Nakamura, Shuho Gotoh, Kota Kurisu

“…The haemorrhage location will be limited to the basal ganglia and thalamus. Approximately 50 mL of bone marrow will be extracted from the iliac bone of each patient, and BMSCs will be cultured using autologous platelet lysate. 3 days before transplantation, BMSCs will be combined with the scaffold to generate HUFF-01. …”
Get full text

Increased dopamine D2/D3 receptor and serotonin transporter availability in male rats after spontaneous remission from repeated social defeat-induced depression; a PET study in rat... by Rodrigo Moraga-Amaro, Daniel Aaron Vazquez-Matias, Luiza Reali Nazario, Rudi A.J.O. Dierckx, Jimmy Stehberg, Janine Doorduin, Erik F.J. de Vries

“…Rats that recovered from depressive-like symptoms showed decreased D2/D3 receptor binding in the caudate putamen and increased SERT availability in the brainstem, insular cortex, midbrain and thalamus, compared to control non-stressed animals. …”
Get full text

Fisetin attenuates AlCl3-induced neurodegeneration by modulating oxidative stress and inflammatory cytokine release in adult albino wistar rats. by Emeka Anyanwu G, Jacinta Nwachukwu I, Rademene Oria S, Kosisochukwu Obasi K, Precious Ekwueme E, Nto Nto J, Chinyere Anyanwu N

“…Furthermore, histopathological evaluations of the thalamus were carried out using routine Hematoxylin and Eosin (H&E) and Cresyl Fast Violet (CFV) techniques while expressions of Glial Fibrillary Acidic Protein (GFAP) for astrocytes, and Ionized Calcium Binding Adapter Molecule 1 (IBA1) for microglia, were examined by immunohistochemical methods. …”
Get full text

Iron deposition is associated with motor and non-motor network breakdown in parkinsonism by Fangda Leng, Yue Gao, Fan Li, Luhua Wei, Yunchuang Sun, Fang Liu, Ying Zhu, Jianxing Qiu, Zhaoxia Wang, Yiwei Zhang

“…To further validate the findings, 13 healthy controls and 37 PD patients who had available T1 and rs-fMRI scans were selected from Parkinson’s progression markers initiative (PPMI) database, and network analysis was performed.ResultsIn local cohort, compared to PD, MSA patients showed greater iron deposition in putamen, while PSP patients had greater iron deposition in caudate nucleus and thalamus. Cerebellar and language networks showed significant difference across diagnostic groups, while default mode network and sensorimotor network did not. …”
Get full text

Apallic syndrome of toxic origin: the diagnostic criteria by N.V. Kurdil, A.O. Volosovets, O.V. Ivashchenko, V.S. Lisovska, H.M. Balan, O.M. Rozhkova, V.V. Andriushchenko

“…The visualization zones of the pathological process in the brain in case of toxic damage are mainly basal ganglia and/or thalamus and dentate nucleus, cortical zone of grey matter, periventricular zone of white matter, corticospinal tract and corpus callosum; asymmetric white matter damage as a sign of demyelination; parietal-occipital subcortical vasogenic edema and lesions of the central pons are characteristic. …”
Get full text

Deciphering network dysregulations and temporo-spatial dynamics in disorders of consciousness: insights from minimum spanning tree analysis by Yangyang Dai, Qiheng He, Shan Wang, Tianqing Cao, Xiaoke Chai, Nan Wang, Yijun Dong, Peiling Wong, Jianghong He, Feng Duan, Yi Yang, Yi Yang, Yi Yang, Yi Yang

“…The increased temporal variability in multiple brain regions within resting-state networks associated with consciousness was detected in MCS patients and VS patients, especially thalamus. As well, the increased spatial variability in multiple brain regions within these resting-state networks was detected in MCS patients and VS patients. …”
Get full text

Coherent Changes in Neural Motor Network Activity during Levodopa-Induced Dyskinesia in a Rat Model of Parkinson’s Disease by Elena S. Brazhnik, Ivan E. Mysin, Lyudmila B. Popova, Vladislav V. Minaychev, Nikolay I. Novikov

“…Local field potentials (LFPs) and neuronal activity were recorded from electrodes implanted in the motor cortex (MCx), ventromedial nucleus of the thalamus (VM), and substantia nigra pars reticulata nucleus (SNpr). …”
Get full text

Individualized gray matter morphological abnormalities unveil two neuroanatomical obsessive-compulsive disorder subtypes by Baohong Wen, Keke Fang, Qiuying Tao, Ya Tian, Lianjie Niu, Wenqing Shi, Zijun Liu, Jin Sun, Liang Liu, Xiaopan Zhang, Ruiping Zheng, Hui-Rong Guo, Yarui Wei, Yong Zhang, Jingliang Cheng, Shaoqiang Han

“…Specifically, subtype 1 showed disease epicenters in the middle frontal gyrus, while subtype 2 displayed disease epicenters in the striatum, thalamus and hippocampus. Furthermore, structural brain abnormalities in these subtypes displayed distinct associations with neurotransmitter receptors/transporters. …”
Get full text

Investigation of choroid plexus variability in schizophrenia-spectrum disorders—insights from a multimodal study by Vladislav Yakimov, Joanna Moussiopoulou, Lukas Roell, Marcel S. Kallweit, Emanuel Boudriot, Matin Mortazavi, Sergi Papiol, Lenka Krčmář, Mattia Campana, Eva C. Schulte, Nicolas Glaichenhaus, Emanuela Martinuzzi, Sean Halstead, Nicola Warren, Dan Siskind, Isabel Maurus, Alkomiet Hasan, Peter Falkai, Andrea Schmitt, Florian J. Raabe, CDP Working Group, Daniel Keeser, Elias Wagner

“…Larger ChP volume was associated with higher volumes of hippocampus, putamen, and thalamus in SSD but not in HC. This study suggests that ChP variability, but not mean volume, is increased in individuals with SSD, compared to HC. …”
Get full text

Berberine alleviates chronic pain-induced anxiety-like behaviors by inhibiting the activation of VLT-projecting cACC (Cg2) neurons by Min He, Ye-Xiang Chen, Pei-Pei Feng, Jie Chen, Chi Xu, Shu-Ting Zhou, Bo-Yu Liu, Xiao-Fen He, Xiao-Mei Shao, Jian-Qiao Fang, Zui Shen, Jing-Gen Liu

“…Here, we found that neurons in cingulate area 2 (Cg2) of the caudal anterior cingulate cortex (cACC), but not in Cg1 of the cACC, projected to the ventral lateral thalamus (VLT). Next, we induced chronic inflammatory pain by plantar injection of complete Freund’s adjuvant (CFA) and observed stable anxiety-like behaviors until two weeks postinjection. …”
Get full text