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221
Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals
Published 2024-12-01“…Also addressed are plant-derived anti-cancer vaccines, nanoparticles, monoclonal antibodies, and immunotherapies. This review article brings to light the importance of plants and plant-based platforms as invaluable, low-cost sources of anti-cancer molecules of particular applicability in resource-poor developing countries.…”
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222
Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics
Published 2024-01-01“…These results were controversial primarily because of the involvement of several interacting enzymes in the Cy metabolic pathway, which can also be affected by several clinical factors as well as other drug interactions. In this review article, we present the effect of CYP2B6 polymorphisms on Cy kinetics since it is the main bioactivating enzyme, as well as discussing all previously reported enzymes and clinical factors that can alter Cy efficacy. …”
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223
Epigenetic regulation of bone remodeling and its role in the pathogenesis of primary osteoporosis
Published 2023-07-01“…Systematisation of these data is important to investigate the differences in epigenetic marker arrays by race and ethnicity. The review article analyses references to relevant reviews and original articles, classifies information on current advances in the study of epigenetic mechanisms in osteoporosis and reviews the results of studies of epigenetic mechanisms on individual links of bone remodelling.…”
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224
Role of phytochemicals in cardiovascular disease management: Insights into mechanisms, efficacy, and clinical application
Published 2025-02-01“…Phytochemicals and bioactive compounds of plant origin have attracted much interest due to their potential role in reducing the risk of cardiovascular diseases. This review article aims to discuss phytochemicals in CVD management, including their mechanisms of action, benefits, and applications in detail. …”
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225
Understanding the Impact of the Sirtuin 1 (SIRT1) Gene on Age-related Macular Degeneration: A Comprehensive Study
Published 2024-04-01“…The disease manifests primarily in two forms, neovascular and non-neovascular, with genetic, environmental and lifestyle factors playing a pivotal role in disease susceptibility and progression. This review article involved conducting an extensive search across various databases, including Google Scholar, PubMed, Web of Science, ScienceDirect, Scopus and EMBASE, to compile relevant case–control studies and literature reviews from online published articles extracted using search terms related to the work. …”
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226
Mitochondrial transplantation for cardioprotection and induction of angiogenesis in ischemic heart disease
Published 2025-02-01“…We hope that data from the current review article help us understand the molecular and cellular mechanisms by which transplanted mitochondria exert their regenerative properties in the ischemic myocardium.…”
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227
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228
In-Depth Exploration of Human Gut Microbiota: A Review
Published 2024-12-01“…Balanced diet, genetic makeup, and use of antibiotics highly influence the microbial population in the gastrointestinal tract. This review article presents a detailed background on the gut microbiota, including its composition and the various factors influencing its diversity and stability. …”
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229
A Review of Digital Pixel Sensors
Published 2025-01-01“…Nonetheless, designing compact conversion circuits along with strategic integration of 3D architectural paradigms can be a potential remedy to the prevailing situation. This review article presents a comprehensive overview of the vast area of DPS technology. …”
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230
The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy
Published 2018-01-01“…Maturation of the luteinizing hormone-releasing hormone secretion pattern in girls in puberty is closely related to changes in the sleep-wake cycle and could have relevance in the pathogenesis of polycystic ovary syndrome. This review article focuses on two main issues in the polycystic ovary syndrome-metabolic syndrome phenotype development: (a) the impact of androgen excess on white adipose tissue function and (b) the possible efficacy of adjuvant melatonin therapy to improve the chronobiologic profile in polycystic ovary syndrome-metabolic syndrome individuals. …”
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231
Mesenchymal Stem Cell–Sourced Exosomes as Potentially Novel Remedies for Severe Dry Eye Disease
Published 2025-01-01“…Therefore, in this review article, we summarized the current knowledge regarding molecular and cellular mechanisms which were responsible for trophic, anti-inflammatory, immunoregulatory, and regenerative properties of MSC-Exos in the treatment of severe DED. …”
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232
Revisiting shallow glauconite factories: intertwined fates of glauconite and iron
Published 2024-11-01“…Typically, for relatively shallow environments, the distal portion of continental shelves is considered the most suitable formation environment. This review article makes it possible to broaden the spectrum of environments favorable to the growth of glauconite, by identifying environments that experience very shallow deposition depths and relatively high sedimentation rates. …”
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233
Cell Therapy in Patients with Critical Limb Ischemia
Published 2015-01-01“…These are based on stimulation of angiogenesis by extracellular and cellular components. This review article carries out a systematic analysis of the most recent scientific literature on the application of stem cells in patients with CLI. …”
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234
Conventional Control Strategies in Building Energy Management
Published 2025-01-01“…Buildings account for a significant portion of worldwide energy consumption, making effective energy management in this sector crucial for reducing electricity costs and mitigating greenhouse gas emissions. This review article provides a comprehensive overview of conventional control methods used in building energy management, drawing from the latest research published in international journals and conferences. …”
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235
Antioxidant Properties of Albumin and Diseases Related to Obstetrics and Gynecology
Published 2025-01-01“…Therefore, based on recent research findings, this review article delves into the molecular and biochemical aspects of albumin’s antioxidative capabilities. …”
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236
Phylogeny, Phytomedicines, Phytochemistry, Pharmacological Properties, and Toxicity of Croton gratissimus Burch (Euphorbiaceae)
Published 2022-01-01“…Authentic literature sources such as books, peer reviewed articles, journals, theses, Google Scholar, Science Direct, and any other validated internet source have been used to develop this review. …”
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237
Advances in Drug Targeting, Drug Delivery, and Nanotechnology Applications: Therapeutic Significance in Cancer Treatment
Published 2025-01-01“…Various drug delivery systems (DDS) were investigated and discussed in this review article. The first part discussed active and passive delivery systems, hydrogels, thermoplastics, microdevices and transdermal-based drug delivery systems. …”
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238
Image Quality and Dose Comparison of Single-Energy CT (SECT) and Dual-Energy CT (DECT)
Published 2020-01-01“…SECT and DECT have developed CT diagnostic potentials in several means. In this review article we have discussed the basic principles of single-energy and dual-energy computed tomography and their important physical differences which can cause better diagnostic evaluation. …”
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239
Exploring the Potential of Blockchain Technology in an IoT-Enabled Environment: A Review
Published 2024-01-01“…Blockchain technology can enhance IoT security by providing decentralized consensus, immutability, and transparent transaction records, ensuring secure and trustworthy communication and data integrity. This review article gives a succinct but thorough understanding of blockchain technology, covering architecture of blockchain, working principles, types, applications, platforms, and its role in the IoT environment. …”
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240
Distinct Roles of Wnt/β-Catenin Signaling in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis
Published 2017-01-01“…These studies thus imply distinct mechanisms of Wnt/β-catenin signaling in the pathogenesis of these two chronic pulmonary diseases, indicating potential targets for COPD and IPF treatments. This review article aims to summarize the involvement and pathogenic roles of Wnt signaling pathways in the COPD and IPF, with a focus on the implication of Wnt/β-catenin signaling as underlying mechanisms and therapeutic targets in these two incurable diseases.…”
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