-
2121
Genome-wide characterization of the MADS-box gene family in Paeonia ostii and expression analysis of genes related to floral organ development
Published 2025-01-01“…Analysis of the cis-acting elements revealed that the 110 PoMADS genes contained different kinds of hormones and stress-related cis-acting elements in their promoter regions. …”
Get full text
Article -
2122
Decoding mutational signatures in breast cancer: Insights from a multi-cohort study
Published 2025-03-01“…Purpose: Diagnosis and treatment decisions of hormonal breast cancers (BC) are now guided by genomic mutations determination, combined into mutational signatures, and provide insight into the patients’ genomic landscape. …”
Get full text
Article -
2123
Gonadal aspects, testosterone and estradiol profiles of the Lebranche mullet Mugil liza subjected to different temperatures during the larviculture phase
Published 2025-02-01“…The present study evaluated the influence of different temperatures during Mugil liza larviculture and their late effects on gonadal development and hormonal quantification after 24 months. The fertilized eggs (45 eggs L-1) were initially kept in a 60 L circular tank until hatching. …”
Get full text
Article -
2124
Stress during Lactation Induces Insulin Resistance Associated with an Increase in Type 1 Cannabinoid Receptors in Liver and Adipose Tissue
Published 2019-01-01“…Several reports have shown that stress during lactation causes long-term metabolic and hormonal disruptions. In this study, we designed experiments to evaluate the effects of stress during lactation on the abundance of Type 1 cannabinoid/endocannabinoid receptors (CB1R) in epididymal fat and liver and development of insulin resistance in adult mice. …”
Get full text
Article -
2125
Quantitative Proteomics Analysis Reveals XDH Related with Ovarian Oxidative Stress Involved in Broodiness of Geese
Published 2025-01-01“…The results of this study showed that during the broody period, geese exhibited degraded ovarian tissues, disrupted follicular development, a thinner granulosa cell layer, and lower levels of ovarian hormones E2, P4, and AMH. Antioxidant activity (GSH, CAT, SOD, T-AOC, and the content of H<sub>2</sub>O<sub>2</sub>) and the mRNA expression levels of antioxidant genes (GPX, SOD-1, SOD-2, CAT, COX-2, and Hsp70) were significantly higher in pre-broody geese compared to laying geese, while the expression of apoptosis-related genes (p53, Caspase-3, and Caspase-9) increased and the anti-apoptotic gene Bcl-2 decreased. …”
Get full text
Article -
2126
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women
Published 2017-01-01“…On this basis, we aimed to investigate the potential association between TRAIL and adipokine levels in a cohort of subjects in which age/gender/hormonal interferences were excluded. Methods. Serum levels of TRAIL and a panel of adipokines were measured in postmenopausal women (n=147) stratified according to waist circumference measures as normal, overweight, or obese. …”
Get full text
Article -
2127
Two Novel CYP11B1 Gene Mutations in Patients from Two Croatian Families with 11β-Hydroxylase Deficiency
Published 2014-01-01“…Here, we describe the molecular genetics of two previously reported male siblings in whom diagnosis of 11β-OHD has been established based on their hormonal profiles displaying high levels of 11-deoxycortisol and hyperandrogenism. …”
Get full text
Article -
2128
Genome-wide identification and expression analysis of the PIN gene family in the pepper pedicel abscission zone and during root development
Published 2024-12-01“…CaPINs encompass a multitude of elements associated with growth, environmental responses, and hormonal signaling. Transcriptome data analysis revealed that the expression of CaPINs in pepper was tissue-specific. …”
Get full text
Article -
2129
Factors associated with early-onset androgenetic alopecia: A scoping review.
Published 2024-01-01“…Early-onset AGA may also be associated with hormonal profiles, 5α-reductase enzyme activity, androgen receptor genes, and some susceptibility loci. …”
Get full text
Article -
2130
Bioinformatics analysis combined with experimental validation reveals the biological role of the ILK gene in prostate cancer
Published 2025-01-01“…The integrin-linked kinase (ILK) gene has been identified as an oncogenic driver in hormonal cancers, including PCa. Methods To identify key genes in PCa, we utilized differential gene expression analysis and Weighted Gene Co-expression Network Analysis (WGCNA). …”
Get full text
Article -
2131
Inverse Relationship Between Leydig Cell Density and Metastatic Potential of Prostatic Adenocarcinoma
Published 1999-01-01“…Conclusions: Patients with metastatic adenocarcinoma of prostate, as a group, have a significantly lower Leydig cell density than patients without metastasis or patients without PC in compatible age groups. The hormonal relationship between this observation is however unknown. …”
Get full text
Article -
2132
Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel
Published 2024-12-01“…Specifically, we focused on brain regions integral to behavioral and hormonal control, including the olfactory bulb, hypothalamus, amygdala, and insula. …”
Get full text
Article -
2133
Cosmetic Appeal, HRQoL, and Effectiveness of Simple and Pseudotesticular Techniques of Orchidectomy in Prostate Cancer
Published 2021-01-01“…Orchidectomy is the most cost-effective means of hormonal therapy for locally advanced or metastatic prostate cancer (LAMP). …”
Get full text
Article -
2134
"Cuéntame tus testosteronas": Un análisis sobre las regulaciones para jugadorxs transgénero e hiperandrógenas
Published 2020-01-01“…Si antes el foco estaba enquistado en la genitalidad, en la actualidad se centra en el control hormonal, en ambas situaciones bajo la aplicación de tecnologías de control del cuerpo cuyo fin es disciplinarlo.Con todo, consideramos que poder revisar qué sucede en nuestros contextos locales con las demandas de los colectivos disidentes nos permite repensar nuestras instituciones y aportar una mirada crítica en la deconstrucción y reconstrucción de deportes para todxs.…”
Get full text
Article -
2135
RETRACTED: The role of biofield energy treatment on psychological symptoms, mental health disorders, and stress‐related quality of life in adult subjects: A randomized controlled c...
Published 2023-05-01“…Furthermore, physiological biomarkers: vitamins (B12, C, and D3 metabolites), immune biomarker (CD8+CD28−), neurotransmitters (acetylcholine, noradrenaline, and dopamine), hormones (oxytocin, 17‐β‐estradiol, and insulin), and antiaging protein (klotho) levels were significantly (p ≤ 0.001) increased in treatment group than placebo. …”
Get full text
Article -
2136
Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference
Published 2025-01-01“…In the context of endocrine disorders, molecular therapy is particularly effective in modulating pathogenic mechanisms such as defective insulin signaling, beta-cell dysfunction and hormonal imbalances. Furthermore, siRNA and ASOs have the ability to downregulate overactive signaling pathways that contribute to complex, non-monogenic endocrine disorders, thereby addressing these conditions at their molecular origin. …”
Get full text
Article -
2137
A Dermatological Intervention of Gynecomastia in Young Asian Man with a History of Soy Product Consumption: A Case Report
Published 2025-01-01“…Gynecomastia is common in infants, adolescents, and elderly men, with the most common cause is related to hormonal changes associated with aging. Medical intervention is usually required for true gynecomastia that has lasted more than a year. …”
Get full text
Article -
2138
Extrinsic attributes that drive consumer purchase of block mozzarella
Published 2025-02-01“…Consumers found “produced without added hormones,” “made with milk from our pasture-raised cows,” and “made locally” to be the most appealing label claims. …”
Get full text
Article -
2139
Evaluation of IL-29 in Euthyroid Patients with Graves’ Orbitopathy: A Preliminary Study
Published 2020-01-01“…The following parameters were evaluated in every participant: thyroid-related hormones and autoantibodies and inflammatory markers (white blood cells, hsCRP). …”
Get full text
Article -
2140
A sustainable breakthrough in rodent pest control: laboratory validation of novel neem-andrographolide bait with dual toxic and contraceptive effects
Published 2025-02-01“…Remaining live rats revealed significant reduction in the body weight, weight of reproductive organs, duration of estrous cycle, number of both normal and atretic follicles, and level of sex hormones in all the treated groups. Mating behaviour and reproductive success were also affected in all the treated groups. …”
Get full text
Article