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141
In Search of the Genes of Asthma on the Island of Tristan da Cunha
Published 1995-01-01Get full text
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142
Gene Expression Profiling in Dermatitis Herpetiformis Skin Lesions
Published 2012-01-01“…In order to investigate the pathogenesis of skin lesions at molecular level, we analysed the gene expression profiles in skin biopsies from 6 CD patients with DH and 6 healthy controls using Affymetrix HG-U133A 2.0 arrays. 486 genes were differentially expressed in DH skin compared to normal skin: 225 were upregulated and 261 were downregulated. …”
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143
The mean and noise of stochastic gene transcription with cell division
Published 2018-09-01Get full text
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144
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145
A survey of the Sli gene in wild and cultivated potato
Published 2024-05-01“…One way of incorporating self‐compatibility into incompatible cultivated potato (Solanum tuberosum) germplasm is to introduce the S‐locus inhibitor gene (Sli), which functions as a dominant inhibitor of gametophytic self‐incompatibility. …”
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146
Clinical Relevance of HLA Gene Variants in HBV Infection
Published 2016-01-01“…Host gene variants may influence the natural history of hepatitis B virus (HBV) infection. …”
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147
Studies on the Interleukin-10 Gene in Animal Models of Colitis
Published 2001-01-01“…Interestingly, in IL-10 gene-deficient mice raised in germ-free conditions, the intestinal inflammatory changes normally observed in conventional nongerm-free conditions are not detected, suggesting a role for luminal bacteria in the pathogenesis of the inflammatory process.…”
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148
The Identification of Key Genes and Pathways in Glioma by Bioinformatics Analysis
Published 2017-01-01“…This study aims to explore the potential mechanism and identify gene signatures of glioma. The glioma gene expression profile GSE4290 was analyzed for differentially expressed genes (DEGs). …”
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149
DOSAGE COMPENSATION: REGULATION OF SEX CHROMOSOME GENE EXPRESSION
Published 2014-12-01Subjects: Get full text
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150
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151
Peroxisome Proliferator-Activated Receptor Alpha Target Genes
Published 2010-01-01“…PPARα governs biological processes by altering the expression of a large number of target genes. Accordingly, the specific role of PPARα is directly related to the biological function of its target genes. …”
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152
Identification of Important Genes of Keratoconus and Construction of the Diagnostic Model
Published 2022-01-01“…GSE151631 and GSE77938 were downloaded from the comprehensive gene expression database (GEO). By using the random forest model (RF), support vector machine model (SVM), and generalized linear model (GLM), important immune-related genes were identified as biomarkers for KC diagnosis. …”
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153
The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes
Published 2014-01-01“…In addition, the biogenesis and maintenance of mitochondria, including mitochondrial DNA (mtDNA) replication, transcription, and translation, require nuclear-encoded genes. In the past decade, a growing number of syndromes associated with dysfunction of mtDNA translation have been reported. …”
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154
Engineering tomato disease resistance by manipulating susceptibility genes
Published 2025-02-01Subjects: Get full text
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155
Highly Effective Crosslinker for Redox-Sensitive Gene Carriers
Published 2021-01-01“…Polyethyleneimine (PEI) has been extensively used as a common gene carrier due to its high gene transfection efficiency. …”
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156
Novel Genes Potentially Involved in Fibroblasts of Diabetic Wound
Published 2021-01-01“…In this study, we sought to screen out the novel genes which act important roles in diabetic fibroblasts through bioinformatic methods. …”
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157
Principles and medical applications of gene editing by CRISPR / Cas
Published 2021-12-01“…CRISPR/Cas technology is a simple, fast and extremely efficient method for gene editing. In order to describe the principles and medical application of this technology, a bibliographic review was carried out in Pubmed, SciELO, academic Google and the Cochrane Library, with the descriptors “gene editing”, “genome editing”, “CRISPR-Cas systems”, and “CRISPR-associated protein 9”. …”
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Identification of hub genes and pathways in mouse with cold exposure
Published 2025-01-01Subjects: Get full text
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160
Intricacies for Posttranslational Tumor-Targeted Cytokine Gene Therapy
Published 2013-01-01“…Within the same tumor model, the location of the targeting peptide could either improve or reduce the antitumor effect of interleukin (IL)12 gene treatments, yet in other tumor models the tumor-targeted IL12 plasmid DNAs were equally effective regardless of the peptide location. …”
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