Infiltration of the liver by cells of innate and adaptive immunity and their destruction in development of experimental immune concanavalin-A-induced hepatitis by S. I. Pavlovich, T. M. Bryzgina, N. V. Makogon, L. I. Aleksyuk, T. V. Martynova, R. I. Yanchy, I. N. Alekseyeva

“…Obtained data assume, that infiltration of the liver by leukocytes, in particular neutrophiles, in combination to ascending necrotic destruction of peripheral cells of innate and adaptive immunity can be the essential pathogenic mechanism at inflammatory liver diseases of T-cell origin.…”
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Real-world pharmacovigilance analysis unveils the toxicity profile of amivantamab targeting EGFR exon 20 insertion mutations in non-small cell lung cancer by Jing Zhang, Wenjie Li

“…There were noteworthy incidences of AEs including infusion-related reactions, rash, dyspnea, pneumonitis, paronychia, pulmonary embolism, thrombocytopenia, nausea, acneiform dermatitis, deep vein thrombosis, febrile neutropenia, peripheral edema, hypokalemia, and neutropenia. Furthermore, the majority of AEs occurred within the first month following the initiation of amivantamab treatment, accounting for 51.74% of cases. …”
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Economic Management within the Cossack Frontier in the Second Half of the 19th Century (Based on the Example of the Don and Azov Cossack Troops) by Petr A. Kolpakov, Ivan Yu. Yurchenko

“…The geographical format stems from the historical importance of securing Russia’s southern borders and the related economic measures necessary to support military operations in peripheral regions. The procurement of grain through auctions for Cossack troop officials presented challenges in balancing the interests of the military department with those of commercial suppliers. …”
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Basic fibroblast growth factor helps protect facial nerve cells in a freeze-induced paralysis model. by Shinji Iwata, Hiroyuki Yamada, Masato Teraoka, Takemichi Tanaka, Takuya Kimura, Tomonori Joko, Yasuhiko Tabata, Hiroyuki Wakisaka, Naohito Hato

“…Severe axonal damage in the peripheral nerves results in retrograde degeneration towards the central side, leading to neuronal cell death, eventually resulting in incomplete axonal regeneration and functional recovery. …”
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MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis by Vishesh Khanna, Gohar Eslami, Rochelle Reyes, Robert Diep, Sebastian Fernandez-Pol, Henning Stehr, Carlos Jose Suarez, Harlan Pinto, James M. Ford, Tian Yi Zhang, Christopher T. Chen

“…Her pancytopenia was associated with 20 distinct pathogenic TP53 mutations in peripheral blood and bone marrow not present in drug-resistant tumor tissue. …”
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The link between spreading depolarization and innate immunity in the central nervous system by Kadir Oguzhan Soylu, Muge Yemisci, Hulya Karatas

“…Inflammation extends beyond the central nervous system to peripheral structures, including the meninges and trigeminovascular system, which are critical for headache initiation. …”
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Comparing apples with apples: A proposed taxonomy for "Community Health Workers" and other front-line health workers for international comparisons. by Stephen Hodgins, Uta Lehmann, Henry Perry, Nicholas Leydon, Kerry Scott, Smisha Agarwal, Hannah Marcus, Rajani Ved, Elijah Olivas, Madeleine Ballard, Dickson Mbewe, Margaret Odera, Sherlie Petit Homme, Benard Otieno, Pasipano Wutete, Angeline Chikumba, Prossy Muyingo, John Kyakuha, Emmanuel Harcourt, Morseda Chowdhury, David Musoke, Thadee Niyoyitungira, Abimbola Olaniran, John Koku-Awoonor Williams, Lívia Milena Barbosa de Deus E Méllo, Romário Correia Dos Santos, Isabela Cardoso de Matos Pinto, Ram Shrestha, Salim Sadruddin, Melanie Morrow, Eric Sarriot, Maryse Kok, Bhanu Pratap

“…It also leads to a failure to consider occupational groups not commonly thought of as CHWs-but engaged in PHC service delivery at the most peripheral level-in community-based-PHC planning and management arrangements. …”
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The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study by Keiichiro Suminaga, Takashi Nomizo, Hironori Yoshida, Hiroaki Ozasa

“…Genomic DNA was extracted from peripheral blood leukocytes. We used rs2282055, which is in linkage disequilibrium with rs822336, instead of rs822336, because of its distribution in the Asian patient population. …”
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Reading comprehension beliefs of Mexican pre-service language teachers: a Likert scale study by Moisés Damián Perales-Escudero, Mizael Garduño Buenfil, Vilma Esperanza Portillo Campos

“… This paper aims to report the adaptation of a new version of the Scale of Implicit Theories of Reading Comprehension (ETICOLEC as per its Spanish acronym) with a sample of 77 randomly chosen English majors at a peripheral campus of a small university in the Southeast of Mexico. …”
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TUBERCULOUS ARTHRITIS OF THE ANKLE MIMICKING SYNOVITIS IN CHILD - A CASE REPORT by Erick Yudistira Christanto, Sulis Bayusentono

“…Discussion: Radiologic examination revealed peripheral osseous erosions, reduced bone mineral content, and soft tissue swelling. …”
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Case report: From misdiagnosis to timely detection: a clinical and imaging guide to neurological presentations of diffuse large B-cell lymphoma—insights from six cases by Chunxiao Yang, Zihua Gong, Tao Wang, Huijuan Yuan, Weinan Na, Wei Xie, Shengyuan Yu

“…However, the overlap of clinical and auxiliary examination findings with those of various neurological entities—such as cerebral infarction, demyelination, viral encephalitis, and peripheral neuropathy—often results in diagnostic misattribution.Case presentationWe delineate six pathologically-confirmed DLBCL cases, each heralded by neurological deficits, including limb paresis, sensory loss, vertigo, seizure activity, and aphasia. …”
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REPAIR OF SCIATIC NERVE LESION AUGMENTED WITH AMNION MEMBRANE COMPOSITE AND MESENCHYMAL STEM CELL by Heri Suroto, R. Taufan Mulyo Wibisono

“…Background: Peripheral nerve injuries (PNI) are quite common, with an incidence of 13.9% per 100,000 people per year. …”
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Factors influencing male involvement in family planning among married couples seeking maternity and pediatric services in Chuk by Mercy Nwankwo, Chinenye, Immaculate, Okoth

“…However male involvement in family planning is still minimal with male playing a peripheral role. The aim of the study is to determine the factors influencing male involvement in family planning among married couples seeking maternity and pediatric services from January to June 2016 in CHUK. …”
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Diagnosis and treatment of the irritable bowel syndrome: clinical guidelines of the Russian gastroenterological association and Russian association of coloproctology by V. T. Ivashkin, Yu. A. Shelygin, Ye. K. Baranskaya, Ye. A. Belousova, A. G. Beniashvili, S. V. Vasilyev, A. O. Golovenko, O. V. Golovenko, Ye. G. Grigoryev, N. V. Kostenko, T. L. Lapina, I. D. Loranskaya, O. S. Lyashenko, I. V. Mayev, Ye. A. Poluektova, V. G. Rumyantsev, V. M. Timerbulatov, A. S. Trukhmanov, O. Yu. Fomenko, I. L. Khalif, E. Yu. Chashkova, A. A. Sheptulin, O. S. Shifrin, V. V. Yanovoy

“…Enterokinetic agent prucalopride may be prescribed at inefficacy of laxatives. Peripheral opioid agonists (trimebutine maleate) normalizing intestinal motor activity via action on different subtypes of peripheral opioid receptors, combined plant-derived medication STW 5 are applied as well. …”
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Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…Remestemcel-L-rknd was also associated with improved safety outcomes (_P_<0.05) in 17 out of 30 AEs, including hematologic events, peripheral edema, muscular weakness, nausea, back pain, and fatigue. …”
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Bioactive molecules from soybeans (Glycine max) with anti-type 2 diabetes activity: a systematic review by Adekunle Babajide Rowaiye, Lorretha Chinonye Emenyonu, Ezinne Janefrances Nwonu, Okiemute Ajiroghene Okpalefe, Joseph Akwoba Ogugua, Victor Oluwatoyin Akinseye, Gordon Chukwuma Ibeanu

“… The hallmarks of type 2 diabetes (T2D) include peripheral insulin resistance and insulin insufficiency. …”
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Functional analysis of a novel homozygous missense IVD gene variant: a case report with dual genetic diagnoses by Yuying Zhu, Ke Wu, Hanying Wen

“…Herein, we are the first to report a 5-year-old boy with the blended phenotypes of infantile hypotonia, severe neurodevelopmental disorder, patent ductus arteriosus, cryptorchidism, obesity, distinctive facial features, and elevated isovaleryl carnitine.MethodsTrio-based whole-exome sequencing was performed on genomic DNA from peripheral blood samples from the boy and his parents. …”
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Application of ursodeoxycholic acid at non-alcoholic and alcohol-induced steatohepatitis by Ye. A. Fedos’ina, M. V. Mayevskaya

“…Disorders of carbohydrate metabolism (including insulin resistance) serve as the indication for prescription of drugs, that sensitize peripheral tissues to insulin. At alcohol-induced steatohepatitis abstinence is categorical. …”
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Comparison of anesthetic effects of xylazine combined with alfaxalone or ketamine and maintained with isoflurane in captive Formosan Reeve’s Muntjac (Muntiacus reevesi micrurus) by Li-Jen Chang, Zixuan Wang, Chen-Yeh Lien, Amanda H.C. Wen

“…Induction and recovery times as well as the quality were assessed by a blinded observer. Peripheral oxygen saturation (SpO2), heart rate, respiratory rate, and rectal temperature were recorded for at least 30 min. …”
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Isolated central nervous system relapse in blast crisis of chronic myeloid leukemia: a case report by Hari Priya Raghvan, Caroline Ho Siew Ling, Wee Shiang Yui, Boo Yang Liang, Ehram Jamian, Indhira Subbiah

“…Chronic myeloid leukemia (CML) typically progresses from a chronic phase to an accelerated phase, and eventually to a blast crisis, often involving the bone marrow and peripheral blood, if left untreated. Central nervous system (CNS) involvement is an uncommon manifestation of CML, particularly as an isolated CNS relapse. …”
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