Characteristics, controlling factors of development and exploration areas of deep coal-rock reservoirs in rift basins: a case study of the second member of Cretaceous Nantun Format... by Geng GAO, Yingyi XIE, Beibei HOU, Wenjuan MA, Hui XU, Yujie WANG, Yingdong HUO, Jingyuan ZHANG, Shichao LIU, Wei ZHAO, Yuan LIANG

“…The average permeability is 0.45×10-3 μm2, and the pore structure is mainly microporous, with a high proportion of macropores, making it easier for free gas storage. …”
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Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural c... by Louis-Emmanuel Chriqui, Etienne Abdelnour-Berchtold, Edoardo Zanfrini, Severine Devesa-Perez, Michel Gonzalez, Thorsten Krueger, Kim Ellefsen, Alice Destaillats, David Bonnet, Martin Hübner, Hasna Bouchaab, Michal Bassani-Sternberg, Solange Peters, Sabrina Cavin, Jean Y Perentes

“…Cisplatin (7.5–12–5–35–70 mg/m2) heated at 39±1 °C is delivered into the thoracic cavity before the surgical effusion management. …”
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Independent and joint associations of neighbourhood greenness and walkability with transportational and recreational physical activity among youth and adults in Canada by Natalie Doan, Sebastian A. Srugo, Stephanie A. Prince, Rachel C. Colley, Daniel G. Rainham, Taru Manyanga, Gregory P. Butler, Richard Larouche, Sarah E. Turner, Justin J. Lang

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Treating drug-resistant tuberculosis in an era of shorter regimens: Insights from rural South Africa by J-D K Lotz, J Porter, H Conradie, T Boyles, B Gaunt, S Dimanda, D Cort

“…Injectables (adjusted odds ratio (aOR) 3.00, 95% confidence interval (CI) 1.48 - 6.09), bedaquiline (aOR 3.16, 95% CI 1.36 - 7.35), increasing age (aOR 0.97, 95% CI 0.95 - 0.99) and HIV viraemia defined as final HIV-RNA viral load >1 000 copies/mL (aOR 0.16, 95% CI 0.07 - 0.37) were all significantly and independently associated with treatment success. …”
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Nymphaea pubescens Willd. extract and its flavonoid constituents vasodilate rat isolated pulmonary artery via NO-sGC-cGMP pathway by Teerapap Panklai, Prapapan Temkitthawon, Nungruthai Suphrom, Corine Girard, Perle Totoson, Kowit Hengphasatporn, Yasuteru Shigeta, Krongkarn Chootip, Kornkanok Ingkaninan

“…Compounds 1–3 relaxed both PA and aorta rings with and without endothelium (EC50=26 - >100 µM). VSMCs incubated with the WLE for 1 hr showed no acute cytotoxicity. …”
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Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject ‘cold’ tumors by Laetitia Fend, Eric Quemeneur, Monika Semmrich, Jean-Baptiste Marchand, Matilda Rehn, Nathalie Silvestre, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Björn Frendeus, Petra Holmkvist, Carolin Svensson, Christelle Remy, Patricia Kleinpeter, Jules Deforges, Fred Junghus, Kirstie L Cleary, Mimoza Bodén

“…Here we assess and identify spatially restricted exposure to a novel strongly Treg-depleting, checkpoint-blocking, vectorized αCTLA-4, as a highly efficacious and potentially safe strategy to target CTLA-4.Methods A novel human IgG1 CTLA-4 antibody (4-E03) was identified using function-first screening for monoclonal antibodies (mAbs) and targets associated with superior Treg-depleting activity. …”
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NALCN expression is down-regulated and associated with immune infiltration in gastric cancer by Xuewei Li, Xuewei Li, Na Wu, Chen Wang, Beibei Pei, Xiaoyan Ma, Jun Xie, Jun Xie, Wenhui Yang

“…Consistent with these findings, the expression trend of NALCN mRNA in the GEO database mirrored the experimental results. …”
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بررسی دیاژنز، ژئوشیمی و کیفیت مخزنی سازند فهلیان در یکی از میادین نفتی جنوب غرب ایران by امیر کاظمی, محمدعلی صالحی, جواد سبحانی, جواد هنرمند, نواب خدائی

“…تخلخل و تراوایی مغزه در بخش مخزنی سازند فهلیان در توالی مورد مطالعه به ترتیب دارای تغییراتی در محدوده 01/0 تا 5/27% و کمتر از 01/0 تا بیشتر از mD 630 می‌باشد. این تغییرات در تخلخل و تراوایی شدیداً وابسته به فرآیندهای دیاژنزی با پیروی از الگوی تغییرات رخساره‌ای است. …”
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Association between Loa loa microfilaremia and anatomical hyposplenia in a rural area of the Republic of Congo: a population-based cross-sectional study by Charlotte Boullé, Elodie Lebredonchel, Jérémy T. Campillo, Valentin Dupasquier, Marlhand C. Hemilembolo, Sébastien D. S. Pion, Jean Claude Djontu, Ludovic Rancé, Philippe Souteyrand, François Missamou, Michel Boussinesq, Francine Ntoumi, Cédric B. Chesnais

“…Blood samples were analyzed for L. loa MFD, Plasmodium-PCR, Anti-Plasmodium falciparum-IgG, total IgM, sickle-cell disease status, and hematological abnormalities. …”
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Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead by Tracy Glass, Frédérique Chammartin, Jochen Ehmer, Thomas Klimkait, Alain Amstutz, Josephine Muhairwe, Irene Ayakaka, Blaise Lukau, Jennifer Anne Brown, Lipontso Motaboli, Malebanye Lerotholi, Maurus Kohler, Kathrin Haenggi, Moliehi Mokete, Makobefo Gladys Chakela, Mpho Kao, Mathebe Kopo, Moleboheng Mokebe, Lorena Urda, Bienvenu Lengo Nsakala, Anna Klicpera, Nadine Tschumi, Niklaus Daniel Labhardt

“…Overall, the proportion of cohort participants with viral suppression to <1000 copies/mL has continually exceeded 90% and has been above 95% since 2020; however, this proportion has consistently been lower among children. …”
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Removal and adsorption kinetics of copper(II) ions from aqueous media on activated carbon in dynamic adsorption on a fixed-bed column by Mve Mfoumou, Charly, Tonda-Mikiéla, Pradel, Ngoye, Francis, Bouassa Mougnala, Spenseur, Mbouiti, Berthy Lionel, Feuya Tchouya, Guy Raymond

“…The best Qsat and E (52.52 mg/g and 55.02%, respectively) were obtained with 0.01 < x < 0.04 mm, D = 2 mL/min, and h = 3 cm, with Cu2+ concentration and pH constant at 250 mg/L and 6.5, respectively. …”
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Factores clínico-epidemiológicos asociados a litiasis residual en pacientes sometidos a litotricia láser by Saul E. Velázquez-Guerrero, Luis A. Gastélum-Félix, Julio A. Ruiz-Torres, Uziel F. Rodríguez-Muñoz, Juan A. Lugo-Machado

“…El índice de masa corporal (IMC) promedio fue de 30,8 ± DS 6,2 kg/m2. Las comorbilidades incluyeron diabetes mellitus en cinco (20,83 %), hipertensión arterial sistémica en ocho (33,00%), obesidad en nueve (37,50 %) y enfermedad renal crónica en dos (8,33 %). …”
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IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury by Hongshuang Su, Xiaoxi Lin, Ayinuer Paredong, Ayinuer Paredong, Congcong Yao, Yan Zhang, Mengke Geng, Yuqian Guan, Lichao Gong, Feng Jiang, Qi Lv, Songtao Shou, Heng Jin

“…Inhibition of the IL-6 receptor by tocilizumab in these cells led to a reduction in cellular senescence, accompanied by decreased of the cell cycle regulatory proteins P53 and P21 in mRNA and protein levels, while alleviating cell cycle arrest. …”
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Computing the time-dependent activity rate using non-declustered and declustered catalogues – a first step towards time-dependent seismic hazard calculations for operational earthq... by D. Montiel-López, S. Molina, S. Molina, J. J. Galiana-Merino, J. J. Galiana-Merino, I. Gómez, I. Gómez, A. Kharazian, J. L. Soler-Llorens, J. A. Huesca-Tortosa, A. Guardiola-Villora, G. Ortuño-Sáez

“…The first one is located in Central Italy, where the L'Aquila earthquake happened, while the other is in south-eastern Spain, where several earthquakes with a moment magnitude (<span class="inline-formula"><i>M</i>_w</span>) greater than 4.0 have taken place over the last 30 years, including two earthquakes with magnitude greater than or equal to 5.0. …”
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Adoptive cell transfer of piezo-activated macrophage rescues immunosuppressed rodents from life-threating bacterial infections by Xiaoyi Liu, Wenxiu Xu, Junkun Feng, Ying Wang, Kai Li, Yi Chen, Wenjun Wang, Weiwei Zhao, Shaohua Ge, Jianhua Li

“…Moreover, we test the use of these piezo-activated macrophages (piezoMϕ) as adoptive cell therapy (ACT) for treating various immunosuppressive bacterial infections, including sepsis, pneumonia and peritonitis. …”
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Fotobiomodulación vascular en el tratamiento de niños con transtornos temporomandibulares by María Roxana Ferreira Sertaje, Lara Motta Jansiski, Anna Carolina Ratto Tempestini Horliana, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Ana Paula Taboada Sobral, Natalia Osorio Viarengo, Ana Laura Fossati, Laura Hermida, Andrea Oliver Gomes, Marcela Leticia Leal Gonçalves, Sandra Kalil Bussadori

“…El  láser que se usó es de la marca DMC Therapy Ec potencia 100 mW ±20%, longitud de onda 660nm ±10  nm, rojo, el parámetro de energía 120J, de aplicación continua. …”
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Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial by Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt

“…The following scales/questionnaires were employed: Post-COVID-19 functional status scale, mMRC dyspnea Scale, SF-36, Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS), Memory failures in everyday life following severe head injury, and Visual Analogic Scale (VAS). …”
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Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

“…NMM exhibited a minimum inhibitory concentration (MIC) of 5 μM against S. aureus USA300, impacting cell division and the cell wall by repressing the expressions of genes in the division cell wall (dcw) gene cluster. …”
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Joint effects of temperature and humidity with PM2.5 on COPD by Huan Minh Tran, Feng-Jen Tsai, Yuan-Hung Wang, Kang-Yun Lee, Jer-Hwa Chang, Chi-Li Chung, Chien-Hua Tseng, Chien-Ling Su, Yuan-Chien Lin, Tzu-Tao Chen, Kuan-Yuan Chen, Shu-Chuan Ho, Feng-Ming Yang, Sheng-Ming Wu, Kian Fan Chung, Kin-Fai Ho, Kai-Jen Chuang, Hsiao-Chi Chuang

“…Results We observed that a 1 µg/m3 increase in PM2.5 7-day and 1-month mean was associated with a 1.05-fold and 1.06-fold increase in OR of COPD (p < 0.05). …”
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Determinación de las concentraciones de fluoruro sistémico con uso de biomarcadores ungueales de exposición crónica en población uruguaya en zonas geográficas de riesgo: Resultados... by Estefanía Sicco, Rogelio González-González, José Manuel Salas-Pacheco, Nelly Molina-Frechero, Omar Tremillo-Maldonado, Guillermo Grazioli, Lauren Frenzel Schuch, Felipe Martins Silveira, Vanesa Pereira Prado, Ronell Bologna-Molina

“…Resultados: Mediante la evaluación inicial de fluoruro en uñas y agua de escolares, se registraron concentraciones superiores a los valores establecidos como óptimos por la OMS (0,5-1,0 p.p.m.), verificando una asociación entre los niveles de fluoruro cuantificados. …”
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